Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ET743_HELA_UP |
| Enrichment Score (ES) | 0.59772116 |
| Normalized Enrichment Score (NES) | 1.8388809 |
| Nominal p-value | 0.0017857143 |
| FDR q-value | 0.020025982 |
| FWER p-Value | 0.882 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 2 | 1.254 | 0.1501 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 11 | 0.884 | 0.2555 | Yes |
| 3 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 24 | 0.780 | 0.3480 | Yes |
| 4 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 25 | 0.771 | 0.4404 | Yes |
| 5 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 228 | 0.365 | 0.4690 | Yes |
| 6 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 310 | 0.299 | 0.4988 | Yes |
| 7 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 313 | 0.297 | 0.5343 | Yes |
| 8 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 472 | 0.237 | 0.5507 | Yes |
| 9 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 614 | 0.204 | 0.5646 | Yes |
| 10 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 736 | 0.179 | 0.5769 | Yes |
| 11 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 743 | 0.177 | 0.5977 | Yes |
| 12 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 1305 | 0.119 | 0.5699 | No |
| 13 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 1349 | 0.116 | 0.5806 | No |
| 14 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 1598 | 0.103 | 0.5742 | No |
| 15 | AES | AES Entrez, Source | amino-terminal enhancer of split | 2144 | 0.079 | 0.5427 | No |
| 16 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2460 | 0.069 | 0.5273 | No |
| 17 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 2779 | 0.061 | 0.5107 | No |
| 18 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 2925 | 0.057 | 0.5066 | No |
| 19 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 3347 | 0.046 | 0.4805 | No |
| 20 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | 0.4737 | No |
| 21 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 3703 | 0.039 | 0.4636 | No |
| 22 | CLU | CLU Entrez, Source | clusterin | 3739 | 0.038 | 0.4655 | No |
| 23 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3854 | 0.036 | 0.4612 | No |
| 24 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 4048 | 0.032 | 0.4505 | No |
| 25 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 4332 | 0.027 | 0.4324 | No |
| 26 | CPE | CPE Entrez, Source | carboxypeptidase E | 4444 | 0.025 | 0.4270 | No |
| 27 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 5439 | 0.008 | 0.3533 | No |
| 28 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5981 | 0.000 | 0.3126 | No |
| 29 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 7951 | -0.030 | 0.1682 | No |
| 30 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 8297 | -0.036 | 0.1465 | No |
| 31 | ASNS | ASNS Entrez, Source | asparagine synthetase | 8596 | -0.040 | 0.1290 | No |
| 32 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 9192 | -0.050 | 0.0903 | No |
| 33 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 9982 | -0.066 | 0.0389 | No |
| 34 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 10004 | -0.066 | 0.0453 | No |
| 35 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 10152 | -0.069 | 0.0425 | No |
| 36 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 10785 | -0.085 | 0.0052 | No |
| 37 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 11341 | -0.100 | -0.0246 | No |
| 38 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 12198 | -0.137 | -0.0725 | No |
| 39 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12802 | -0.185 | -0.0956 | No |
| 40 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 13196 | -0.299 | -0.0894 | No |
| 41 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 13274 | -0.389 | -0.0486 | No |
| 42 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 13300 | -0.447 | 0.0032 | No |
