Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetEXTRACELLULAR_REGION
Enrichment Score (ES)0.4457605
Normalized Enrichment Score (NES)1.8484057
Nominal p-value0.0
FDR q-value0.018659651
FWER p-Value0.848
Table: GSEA Results Summary



Fig 1: Enrichment plot: EXTRACELLULAR_REGION   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NPYNPY
Entrez,  Source
neuropeptide Y51.1920.0348Yes
2COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 261.1540.0689Yes
3COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)210.7850.0910Yes
4CTGFCTGF
Entrez,  Source
connective tissue growth factor270.7570.1130Yes
5COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2340.7140.1336Yes
6LPLLPL
Entrez,  Source
lipoprotein lipase450.6710.1526Yes
7CCL20CCL20
Entrez,  Source
chemokine (C-C motif) ligand 20500.6410.1712Yes
8MGPMGP
Entrez,  Source
matrix Gla protein520.6340.1899Yes
9FSTL1FSTL1
Entrez,  Source
follistatin-like 1910.5310.2026Yes
10ADMADM
Entrez,  Source
adrenomedullin960.5230.2178Yes
11CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 21380.4580.2282Yes
12CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 21450.4520.2411Yes
13LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)1530.4420.2536Yes
14F13A1F13A1
Entrez,  Source
coagulation factor XIII, A1 polypeptide1630.4300.2656Yes
15PGCPPGCP
Entrez,  Source
-1830.4040.2761Yes
16GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)1990.3910.2865Yes
17PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein2040.3830.2975Yes
18CDH13CDH13
Entrez,  Source
cadherin 13, H-cadherin (heart)2230.3660.3069Yes
19SPINT1SPINT1
Entrez,  Source
serine peptidase inhibitor, Kunitz type 12440.3500.3157Yes
20LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)2520.3420.3253Yes
21EDN1EDN1
Entrez,  Source
endothelin 13260.2910.3283Yes
22GDF15GDF15
Entrez,  Source
growth differentiation factor 153850.2670.3317Yes
23LAMB2LAMB2
Entrez,  Source
laminin, beta 2 (laminin S)4330.2490.3355Yes
24RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma4580.2420.3408Yes
25EFEMP2EFEMP2
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 24820.2340.3459Yes
26GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)4830.2330.3528Yes
27ANGPTL4ANGPTL4
Entrez,  Source
angiopoietin-like 44930.2300.3589Yes
28IGFBP1IGFBP1
Entrez,  Source
insulin-like growth factor binding protein 15840.2090.3582Yes
29SGCESGCE
Entrez,  Source
sarcoglycan, epsilon6500.1970.3590Yes
30TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 26590.1950.3642Yes
31USH2AUSH2A
Entrez,  Source
Usher syndrome 2A (autosomal recessive, mild)6840.1870.3678Yes
32NUCB2NUCB2
Entrez,  Source
nucleobindin 27430.1770.3686Yes
33IL6RIL6R
Entrez,  Source
interleukin 6 receptor7610.1760.3725Yes
34FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)7890.1720.3755Yes
35LBPLBP
Entrez,  Source
lipopolysaccharide binding protein7900.1710.3806Yes
36WFDC2WFDC2
Entrez,  Source
WAP four-disulfide core domain 28050.1690.3845Yes
37PPT1PPT1
Entrez,  Source
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)8100.1680.3892Yes
38TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)8210.1660.3933Yes
39CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 18370.1640.3970Yes
40CCL7CCL7
Entrez,  Source
chemokine (C-C motif) ligand 78600.1610.4001Yes
41COLQCOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase8880.1570.4027Yes
42ERBB2ERBB2
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)9160.1540.4052Yes
43LOXL1LOXL1
Entrez,  Source
lysyl oxidase-like 110350.1430.4004Yes
44CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)10410.1420.4042Yes
45ADAMTS5ADAMTS5
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)10520.1410.4076Yes
46MMP11MMP11
Entrez,  Source
matrix metallopeptidase 11 (stromelysin 3)10780.1380.4097Yes
47APOA5APOA5
Entrez,  Source
apolipoprotein A-V11260.1340.4101Yes
48LGALS3BPLGALS3BP
Entrez,  Source
lectin, galactoside-binding, soluble, 3 binding protein11320.1340.4136Yes
49IL1BIL1B
Entrez,  Source
interleukin 1, beta11970.1280.4125Yes
50C1QAC1QA
Entrez,  Source
complement component 1, q subcomponent, A chain12200.1260.4146Yes
51EPOEPO
Entrez,  Source
erythropoietin12350.1250.4172Yes
52VTNVTN
Entrez,  Source
vitronectin12390.1240.4206Yes
53TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 212410.1240.4242Yes
54RNASE6RNASE6
Entrez,  Source
ribonuclease, RNase A family, k612460.1240.4276Yes
55PCSK2PCSK2
Entrez,  Source
proprotein convertase subtilisin/kexin type 212780.1220.4288Yes
56WNT2BWNT2B
Entrez,  Source
wingless-type MMTV integration site family, member 2B12840.1210.4320Yes
57SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 513140.1190.4333Yes
58MMP7MMP7
Entrez,  Source
matrix metallopeptidase 7 (matrilysin, uterine)13420.1170.4347Yes
59NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)13490.1160.4376Yes
60NUCB1NUCB1
Entrez,  Source
nucleobindin 113530.1160.4408Yes
61PRSS8PRSS8
Entrez,  Source
protease, serine, 8 (prostasin)13850.1140.4418Yes
62EGFL6EGFL6
Entrez,  Source
EGF-like-domain, multiple 614320.1120.4416Yes
63DMBT1DMBT1
Entrez,  Source
deleted in malignant brain tumors 115080.1080.4390Yes
64FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 115320.1060.4404Yes
65SFRP1SFRP1
Entrez,  Source
secreted frizzled-related protein 115460.1050.4425Yes
66APOA2APOA2
Entrez,  Source
apolipoprotein A-II15960.1030.4418Yes
67ADFPADFP
Entrez,  Source
adipose differentiation-related protein16260.1010.4426Yes
68FBN1FBN1
Entrez,  Source
fibrillin 116430.1000.4443Yes
69COL11A1COL11A1
Entrez,  Source
collagen, type XI, alpha 117490.0950.4391Yes
70AFMAFM
Entrez,  Source
afamin17550.0950.4415Yes
71COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 418020.0930.4407Yes
72NPPBNPPB
Entrez,  Source
natriuretic peptide precursor B18280.0920.4415Yes
73HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor18490.0910.4426Yes
74APOA1APOA1
Entrez,  Source
apolipoprotein A-I18860.0890.4425Yes
75APPAPP
Entrez,  Source
amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)18900.0890.4449Yes
76COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 119420.0870.4436Yes
77SEMA3ASEMA3A
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A19820.0860.4431Yes
78TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia19910.0850.4450Yes
79IL13RA2IL13RA2
Entrez,  Source
interleukin 13 receptor, alpha 220180.0840.4455Yes
80CPB2CPB2
Entrez,  Source
carboxypeptidase B2 (plasma, carboxypeptidase U)20480.0830.4458Yes
81APOEAPOE
Entrez,  Source
apolipoprotein E21230.0800.4425No
82IMPG1IMPG1
Entrez,  Source
interphotoreceptor matrix proteoglycan 122020.0770.4388No
83FGF10FGF10
Entrez,  Source
fibroblast growth factor 1022950.0740.4339No
84SCGB1D2SCGB1D2
Entrez,  Source
secretoglobin, family 1D, member 223390.0730.4328No
85TINAGTINAG
Entrez,  Source
tubulointerstitial nephritis antigen23720.0720.4324No
86FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)23880.0710.4334No
87CSF3CSF3
Entrez,  Source
colony stimulating factor 3 (granulocyte)24830.0690.4282No
88PSAPPSAP
Entrez,  Source
prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy)26420.0640.4180No
89COL5A1COL5A1
Entrez,  Source
collagen, type V, alpha 126600.0630.4185No
90GPC1GPC1
Entrez,  Source
glypican 126720.0630.4196No
91AGGF1AGGF1
Entrez,  Source
angiogenic factor with G patch and FHA domains 127670.0610.4142No
92PRSS2PRSS2
Entrez,  Source
protease, serine, 2 (trypsin 2)27940.0600.4139No
93SPG7SPG7
Entrez,  Source
spastic paraplegia 7, paraplegin (pure and complicated autosomal recessive)28610.0590.4106No
94HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 128800.0580.4110No
95SGCGSGCG
Entrez,  Source
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)29050.0570.4108No
96EFNA5EFNA5
Entrez,  Source
ephrin-A529110.0570.4121No
97DKK3DKK3
Entrez,  Source
dickkopf homolog 3 (Xenopus laevis)29750.0550.4089No
98EREGEREG
Entrez,  Source
epiregulin30110.0540.4078No
99C1QBC1QB
Entrez,  Source
complement component 1, q subcomponent, B chain30170.0540.4090No
100LTBP2LTBP2
Entrez,  Source
latent transforming growth factor beta binding protein 231070.0520.4037No
101MSMBMSMB
Entrez,  Source
microseminoprotein, beta-31340.0510.4033No
102IL5IL5
Entrez,  Source
interleukin 5 (colony-stimulating factor, eosinophil)31400.0510.4044No
103PVRPVR
Entrez,  Source
poliovirus receptor31410.0510.4059No
104DSPPDSPP
Entrez,  Source
dentin sialophosphoprotein31670.0500.4055No
105SPINT2SPINT2
Entrez,  Source
serine peptidase inhibitor, Kunitz type, 232150.0490.4033No
106APODAPOD
Entrez,  Source
apolipoprotein D32550.0480.4017No
107IL5RAIL5RA
Entrez,  Source
interleukin 5 receptor, alpha33050.0470.3994No
108IL18IL18
Entrez,  Source
interleukin 18 (interferon-gamma-inducing factor)33470.0460.3976No
109MEPEMEPE
Entrez,  Source
matrix, extracellular phosphoglycoprotein with ASARM motif (bone)34100.0450.3942No
110COL9A1COL9A1
Entrez,  Source
collagen, type IX, alpha 134130.0450.3953No
111GREM1GREM1
Entrez,  Source
gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)34290.0440.3955No
112GPHA2GPHA2
Entrez,  Source
glycoprotein hormone alpha 234760.0430.3933No
113COL16A1COL16A1
Entrez,  Source
collagen, type XVI, alpha 135300.0420.3905No
114LIPELIPE
Entrez,  Source
lipase, hormone-sensitive36070.0410.3858No
115PRG2PRG2
Entrez,  Source
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)36710.0390.3822No
116PLA2G5PLA2G5
Entrez,  Source
phospholipase A2, group V36910.0390.3819No
117GDNFGDNF
Entrez,  Source
glial cell derived neurotrophic factor37370.0380.3795No
118FXYD6FXYD6
Entrez,  Source
FXYD domain containing ion transport regulator 638020.0360.3757No
119IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)38540.0360.3729No
120ECM1ECM1
Entrez,  Source
extracellular matrix protein 138670.0350.3730No
121RNPEPRNPEP
Entrez,  Source
arginyl aminopeptidase (aminopeptidase B)39060.0350.3711No
122SPNSPN
Entrez,  Source
sialophorin (leukosialin, CD43)40020.0330.3648No
123KLKL
Entrez,  Source
klotho40120.0330.3650No
124UTS2UTS2
Entrez,  Source
urotensin 240340.0320.3644No
125FBLN2FBLN2
Entrez,  Source
fibulin 240530.0320.3640No
126CTF1CTF1
Entrez,  Source
cardiotrophin 141350.0300.3586No
127SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)41940.0290.3551No
128SCRG1SCRG1
Entrez,  Source
-42150.0290.3544No
129LAMA3LAMA3
Entrez,  Source
laminin, alpha 343000.0270.3488No
130IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3043010.0270.3496No
131DLK1DLK1
Entrez,  Source
delta-like 1 homolog (Drosophila)43230.0270.3487No
132DMP1DMP1
Entrez,  Source
dentin matrix acidic phosphoprotein43410.0260.3482No
133FGF21FGF21
Entrez,  Source
fibroblast growth factor 2144520.0240.3405No
134LUMLUM
Entrez,  Source
lumican45330.0230.3351No
135KLK8KLK8
Entrez,  Source
kallikrein 8 (neuropsin/ovasin)46440.0210.3273No
136SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 146970.0200.3239No
137INSL3INSL3
Entrez,  Source
insulin-like 3 (Leydig cell)47410.0190.3211No
138PROK2PROK2
Entrez,  Source
prokineticin 248420.0180.3140No
139ACE2ACE2
Entrez,  Source
angiotensin I converting enzyme (peptidyl-dipeptidase A) 249700.0160.3047No
140MEP1BMEP1B
Entrez,  Source
meprin A, beta49990.0150.3030No
141KLK10KLK10
Entrez,  Source
kallikrein 1050530.0140.2994No
142INHBAINHBA
Entrez,  Source
inhibin, beta A (activin A, activin AB alpha polypeptide)50810.0140.2977No
143FGL2FGL2
Entrez,  Source
fibrinogen-like 250860.0140.2978No
144IL3IL3
Entrez,  Source
interleukin 3 (colony-stimulating factor, multiple)51670.0120.2921No
145PLA2G2APLA2G2A
Entrez,  Source
phospholipase A2, group IIA (platelets, synovial fluid)51990.0120.2900No
146F2F2
Entrez,  Source
coagulation factor II (thrombin)52890.0100.2835No
147SLIT2SLIT2
Entrez,  Source
slit homolog 2 (Drosophila)52930.0100.2836No
148KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)53170.0100.2821No
149SCUBE1SCUBE1
Entrez,  Source
signal peptide, CUB domain, EGF-like 153230.0100.2820No
150ORM1ORM1
Entrez,  Source
orosomucoid 153480.0090.2805No
151TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa54390.0080.2738No
152TFF3TFF3
Entrez,  Source
trefoil factor 3 (intestinal)54800.0080.2710No
153FGF20FGF20
Entrez,  Source
fibroblast growth factor 2054950.0070.2701No
154PGCPGC
Entrez,  Source
progastricsin (pepsinogen C)55210.0070.2684No
155AMHAMH
Entrez,  Source
anti-Mullerian hormone55240.0070.2685No
156CTRLCTRL
Entrez,  Source
chymotrypsin-like55710.0060.2651No
157SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)56140.0050.2621No
158IL15IL15
Entrez,  Source
interleukin 1556740.0050.2577No
159MMP2MMP2
Entrez,  Source
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)57800.0030.2497No
160CCL28CCL28
Entrez,  Source
chemokine (C-C motif) ligand 2858880.0020.2416No
161MMP8MMP8
Entrez,  Source
matrix metallopeptidase 8 (neutrophil collagenase)59090.0010.2401No
162PCSK9PCSK9
Entrez,  Source
proprotein convertase subtilisin/kexin type 959310.0010.2385No
163CCL22CCL22
Entrez,  Source
chemokine (C-C motif) ligand 226089-0.0010.2265No
164CARTPTCARTPT
Entrez,  Source
CART prepropeptide6143-0.0020.2225No
165MUC5ACMUC5AC
Entrez,  Source
mucin 5AC, oligomeric mucus/gel-forming6169-0.0030.2207No
166RTN3RTN3
Entrez,  Source
reticulon 36254-0.0040.2144No
167IL2IL2
Entrez,  Source
interleukin 26369-0.0060.2058No
168CALCACALCA
Entrez,  Source
calcitonin/calcitonin-related polypeptide, alpha6370-0.0060.2060No
169SERPINA1SERPINA1
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16493-0.0080.1969No
170PNLIPRP2PNLIPRP2
Entrez,  Source
pancreatic lipase-related protein 26579-0.0090.1906No
171CCL4CCL4
Entrez,  Source
chemokine (C-C motif) ligand 46591-0.0090.1900No
172IL12BIL12B
Entrez,  Source
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)6624-0.0090.1878No
173MMP10MMP10
Entrez,  Source
matrix metallopeptidase 10 (stromelysin 2)6646-0.0100.1865No
174ANGPTL2ANGPTL2
Entrez,  Source
angiopoietin-like 26736-0.0110.1800No
175CHI3L1CHI3L1
Entrez,  Source
chitinase 3-like 1 (cartilage glycoprotein-39)6833-0.0130.1731No
176LGALS7LGALS7
Entrez,  Source
lectin, galactoside-binding, soluble, 7 (galectin 7)6899-0.0140.1685No
177FGF5FGF5
Entrez,  Source
fibroblast growth factor 56936-0.0140.1661No
178SHHSHH
Entrez,  Source
sonic hedgehog homolog (Drosophila)6999-0.0150.1618No
179MEP1AMEP1A
Entrez,  Source
meprin A, alpha (PABA peptide hydrolase)7009-0.0150.1616No
180LEPLEP
Entrez,  Source
leptin (obesity homolog, mouse)7136-0.0170.1524No
181GHRLGHRL
Entrez,  Source
ghrelin/obestatin preprohormone7162-0.0180.1511No
182LTBP4LTBP4
Entrez,  Source
latent transforming growth factor beta binding protein 47185-0.0180.1499No
183CFHCFH
Entrez,  Source
complement factor H7191-0.0180.1500No
184FGF6FGF6
Entrez,  Source
fibroblast growth factor 67269-0.0190.1447No
185HAPLN1HAPLN1
Entrez,  Source
hyaluronan and proteoglycan link protein 17300-0.0200.1430No
186MATN1MATN1
Entrez,  Source
matrilin 1, cartilage matrix protein7327-0.0200.1416No
187FBN2FBN2
Entrez,  Source
fibrillin 2 (congenital contractural arachnodactyly)7354-0.0200.1402No
188SFRP4SFRP4
Entrez,  Source
secreted frizzled-related protein 47370-0.0210.1397No
189COL15A1COL15A1
Entrez,  Source
collagen, type XV, alpha 17379-0.0210.1397No
190ANGPT2ANGPT2
Entrez,  Source
angiopoietin 27458-0.0220.1343No
191SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))7545-0.0230.1284No
192IL1AIL1A
Entrez,  Source
interleukin 1, alpha7552-0.0230.1287No
193FGF12FGF12
Entrez,  Source
fibroblast growth factor 127595-0.0240.1262No
194INHAINHA
Entrez,  Source
inhibin, alpha7620-0.0240.1250No
195IL12AIL12A
Entrez,  Source
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)7646-0.0250.1239No
196FSTL3FSTL3
Entrez,  Source
follistatin-like 3 (secreted glycoprotein)7760-0.0270.1160No
197C2C2
Entrez,  Source
complement component 27795-0.0270.1142No
198PNLIPRP1PNLIPRP1
Entrez,  Source
pancreatic lipase-related protein 17828-0.0280.1126No
199TMPRSS11DTMPRSS11D
Entrez,  Source
transmembrane protease, serine 11D7878-0.0290.1097No
200TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 17952-0.0300.1049No
201FBLN5FBLN5
Entrez,  Source
fibulin 58019-0.0310.1008No
202LCATLCAT
Entrez,  Source
lecithin-cholesterol acyltransferase8062-0.0320.0985No
203EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 18124-0.0330.0948No
204COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein8125-0.0330.0958No
205PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)8146-0.0330.0952No
206NOGNOG
Entrez,  Source
noggin8217-0.0340.0909No
207FMODFMOD
Entrez,  Source
fibromodulin8247-0.0350.0897No
208THBS4THBS4
Entrez,  Source
thrombospondin 48277-0.0350.0885No
209PNOCPNOC
Entrez,  Source
prepronociceptin8291-0.0360.0886No
210CPCP
Entrez,  Source
ceruloplasmin (ferroxidase)8305-0.0360.0886No
211CRISP1CRISP1
Entrez,  Source
cysteine-rich secretory protein 18354-0.0370.0860No
212VWFVWF
Entrez,  Source
von Willebrand factor8376-0.0370.0855No
213IL18BPIL18BP
Entrez,  Source
interleukin 18 binding protein8393-0.0370.0854No
214FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)8465-0.0380.0811No
215COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha8614-0.0410.0709No
216DNASE1DNASE1
Entrez,  Source
deoxyribonuclease I8630-0.0410.0710No
217EGFL7EGFL7
Entrez,  Source
EGF-like-domain, multiple 78671-0.0410.0692No
218SLIT3SLIT3
Entrez,  Source
slit homolog 3 (Drosophila)8691-0.0420.0689No
219PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone8761-0.0430.0649No
220SSTSST
Entrez,  Source
somatostatin8868-0.0450.0581No
221PCSK1NPCSK1N
Entrez,  Source
proprotein convertase subtilisin/kexin type 1 inhibitor8992-0.0470.0501No
222FGF16FGF16
Entrez,  Source
fibroblast growth factor 169104-0.0490.0431No
223TAC1TAC1
Entrez,  Source
tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)9176-0.0500.0391No
224PLUNCPLUNC
Entrez,  Source
palate, lung and nasal epithelium carcinoma associated9196-0.0500.0391No
225SFTPDSFTPD
Entrez,  Source
surfactant, pulmonary-associated protein D9273-0.0520.0348No
226CHADCHAD
Entrez,  Source
chondroadherin9330-0.0530.0321No
227FGF4FGF4
Entrez,  Source
fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)9333-0.0530.0335No
228HPXHPX
Entrez,  Source
hemopexin9338-0.0530.0348No
229PDZD2PDZD2
Entrez,  Source
PDZ domain containing 29374-0.0540.0337No
230ATRNATRN
Entrez,  Source
attractin9565-0.0570.0208No
231PLA2G10PLA2G10
Entrez,  Source
phospholipase A2, group X9685-0.0600.0135No
232APCSAPCS
Entrez,  Source
amyloid P component, serum9703-0.0600.0139No
233SECTM1SECTM1
Entrez,  Source
secreted and transmembrane 19756-0.0610.0118No
234COL10A1COL10A1
Entrez,  Source
collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia)9784-0.0620.0115No
235FRZBFRZB
Entrez,  Source
frizzled-related protein9829-0.0630.0100No
236MFNGMFNG
Entrez,  Source
manic fringe homolog (Drosophila)9855-0.0630.0100No
237IKIK
Entrez,  Source
IK cytokine, down-regulator of HLA II9896-0.0640.0088No
238FGF18FGF18
Entrez,  Source
fibroblast growth factor 189933-0.0650.0079No
239IL7IL7
Entrez,  Source
interleukin 79952-0.0660.0085No
240FGGFGG
Entrez,  Source
fibrinogen gamma chain9982-0.0660.0082No
241IDEIDE
Entrez,  Source
insulin-degrading enzyme10052-0.0670.0049No
242SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310069-0.0680.0057No
243MMP3MMP3
Entrez,  Source
matrix metallopeptidase 3 (stromelysin 1, progelatinase)10103-0.0680.0052No
244MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response10189-0.0700.0008No
245FGF3FGF3
Entrez,  Source
fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)10191-0.0700.0028No
246CRISP2CRISP2
Entrez,  Source
cysteine-rich secretory protein 210285-0.072-0.0022No
247IL1RNIL1RN
Entrez,  Source
interleukin 1 receptor antagonist10398-0.075-0.0086No
248IMPG2IMPG2
Entrez,  Source
interphotoreceptor matrix proteoglycan 210421-0.075-0.0081No
249TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)10443-0.076-0.0074No
250CLEC11ACLEC11A
Entrez,  Source
C-type lectin domain family 11, member A10483-0.077-0.0081No
251CPN1CPN1
Entrez,  Source
carboxypeptidase N, polypeptide 1, 50kD10726-0.083-0.0242No
252FIGFFIGF
Entrez,  Source
c-fos induced growth factor (vascular endothelial growth factor D)10740-0.084-0.0227No
253FGAFGA
Entrez,  Source
fibrinogen alpha chain10802-0.085-0.0249No
254LGALS8LGALS8
Entrez,  Source
lectin, galactoside-binding, soluble, 8 (galectin 8)10835-0.086-0.0248No
255PLGPLG
Entrez,  Source
plasminogen10845-0.087-0.0229No
256CAV3CAV3
Entrez,  Source
caveolin 310854-0.087-0.0210No
257PTNPTN
Entrez,  Source
pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)10905-0.088-0.0222No
258FGF17FGF17
Entrez,  Source
fibroblast growth factor 1711001-0.090-0.0268No
259REG3AREG3A
Entrez,  Source
regenerating islet-derived 3 alpha11065-0.092-0.0289No
260IL4IL4
Entrez,  Source
interleukin 411204-0.096-0.0366No
261WNT5AWNT5A
Entrez,  Source
wingless-type MMTV integration site family, member 5A11232-0.097-0.0359No
262RNH1RNH1
Entrez,  Source
ribonuclease/angiogenin inhibitor 111262-0.097-0.0352No
263PLA2G2DPLA2G2D
Entrez,  Source
phospholipase A2, group IID11529-0.107-0.0524No
264HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)11565-0.108-0.0519No
265UTP11LUTP11L
Entrez,  Source
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)11595-0.109-0.0509No
266YARSYARS
Entrez,  Source
tyrosyl-tRNA synthetase11607-0.110-0.0485No
267AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)11612-0.110-0.0456No
268MIFMIF
Entrez,  Source
macrophage migration inhibitory factor (glycosylation-inhibiting factor)11668-0.112-0.0465No
269PCSK5PCSK5
Entrez,  Source
proprotein convertase subtilisin/kexin type 511725-0.114-0.0474No
270FGL1FGL1
Entrez,  Source
fibrinogen-like 111767-0.116-0.0471No
271CKLFCKLF
Entrez,  Source
chemokine-like factor11769-0.116-0.0438No
272GRPGRP
Entrez,  Source
gastrin-releasing peptide11774-0.116-0.0407No
273SCYE1SCYE1
Entrez,  Source
small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)11779-0.116-0.0376No
274AMY2AAMY2A
Entrez,  Source
amylase, alpha 2A; pancreatic11899-0.122-0.0431No
275CFHR1CFHR1
Entrez,  Source
complement factor H-related 112082-0.131-0.0532No
276LALBALALBA
Entrez,  Source
lactalbumin, alpha-12107-0.132-0.0511No
277MMP9MMP9
Entrez,  Source
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)12150-0.134-0.0504No
278CPA1CPA1
Entrez,  Source
carboxypeptidase A1 (pancreatic)12469-0.152-0.0702No
279DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)12470-0.153-0.0657No
280COL5A3COL5A3
Entrez,  Source
collagen, type V, alpha 312502-0.155-0.0635No
281IL9RIL9R
Entrez,  Source
interleukin 9 receptor12552-0.159-0.0626No
282FGBFGB
Entrez,  Source
fibrinogen beta chain12598-0.163-0.0612No
283A1BGA1BG
Entrez,  Source
alpha-1-B glycoprotein13096-0.252-0.0919No
284INHBCINHBC
Entrez,  Source
inhibin, beta C13106-0.255-0.0850No
285MBL2MBL2
Entrez,  Source
mannose-binding lectin (protein C) 2, soluble (opsonic defect)13116-0.257-0.0781No
286TFRCTFRC
Entrez,  Source
transferrin receptor (p90, CD71)13197-0.299-0.0754No
287IGFALSIGFALS
Entrez,  Source
insulin-like growth factor binding protein, acid labile subunit13230-0.325-0.0683No
288CXCL9CXCL9
Entrez,  Source
chemokine (C-X-C motif) ligand 913330-0.714-0.0548No
289CD5LCD5L
Entrez,  Source
CD5 molecule-like13336-0.870-0.0295No
290SERPINA7SERPINA7
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 713340-1.0120.0002No
Table: GSEA details [plain text format]



Fig 2: EXTRACELLULAR_REGION   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: EXTRACELLULAR_REGION: Random ES distribution   
Gene set null distribution of ES for EXTRACELLULAR_REGION