Details for gene set GTPASE_REGULATOR

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	GTPASE_REGULATOR_ACTIVITY
Enrichment Score (ES)	0.5371773
Normalized Enrichment Score (NES)	1.8520932
Nominal p-value	0.0066225166
FDR q-value	0.018254172
FWER p-Value	0.838

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	25	0.771	0.0953	Yes
2	RAPGEF4	RAPGEF4 Entrez, Source	Rap guanine nucleotide exchange factor (GEF) 4	66	0.600	0.1679	Yes
3	RGS1	RGS1 Entrez, Source	regulator of G-protein signalling 1	75	0.565	0.2384	Yes
4	RGS16	RGS16 Entrez, Source	regulator of G-protein signalling 16	103	0.505	0.3001	Yes
5	PLCE1	PLCE1 Entrez, Source	phospholipase C, epsilon 1	203	0.384	0.3409	Yes
6	RGS3	RGS3 Entrez, Source	regulator of G-protein signalling 3	338	0.287	0.3670	Yes
7	RAPGEF5	RAPGEF5 Entrez, Source	Rap guanine nucleotide exchange factor (GEF) 5	384	0.267	0.3972	Yes
8	RGS4	RGS4 Entrez, Source	regulator of G-protein signalling 4	454	0.244	0.4227	Yes
9	RGS5	RGS5 Entrez, Source	regulator of G-protein signalling 5	513	0.224	0.4465	Yes
10	CDC42EP2	CDC42EP2 Entrez, Source	CDC42 effector protein (Rho GTPase binding) 2	522	0.222	0.4739	Yes
11	TNK2	TNK2 Entrez, Source	tyrosine kinase, non-receptor, 2	629	0.201	0.4913	Yes
12	ALDH1A1	ALDH1A1 Entrez, Source	aldehyde dehydrogenase 1 family, member A1	739	0.178	0.5055	Yes
13	EIF2B2	EIF2B2 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa	975	0.149	0.5066	Yes
14	PSCD1	PSCD1 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)	1237	0.125	0.5026	Yes
15	RTKN	RTKN Entrez, Source	rhotekin	1496	0.108	0.4968	Yes
16	PSCD2	PSCD2 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)	1498	0.108	0.5104	Yes
17	CDC42SE1	CDC42SE1 Entrez, Source	CDC42 small effector 1	1617	0.102	0.5143	Yes
18	RALGDS	RALGDS Entrez, Source	ral guanine nucleotide dissociation stimulator	1715	0.097	0.5192	Yes
19	ARHGDIB	ARHGDIB Entrez, Source	Rho GDP dissociation inhibitor (GDI) beta	1774	0.094	0.5267	Yes
20	RALBP1	RALBP1 Entrez, Source	ralA binding protein 1	1792	0.093	0.5372	Yes
21	WASL	WASL Entrez, Source	Wiskott-Aldrich syndrome-like	1998	0.085	0.5324	No
22	ERRFI1	ERRFI1 Entrez, Source	ERBB receptor feedback inhibitor 1	2488	0.068	0.5042	No
23	PSCD3	PSCD3 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 3	2590	0.065	0.5048	No
24	RAPGEF3	RAPGEF3 Entrez, Source	Rap guanine nucleotide exchange factor (GEF) 3	2950	0.056	0.4848	No
25	CENTA1	CENTA1 Entrez, Source	centaurin, alpha 1	3441	0.044	0.4535	No
26	RAP1GAP	RAP1GAP Entrez, Source	RAP1 GTPase activating protein	3624	0.040	0.4449	No
27	ARHGEF1	ARHGEF1 Entrez, Source	Rho guanine nucleotide exchange factor (GEF) 1	3821	0.036	0.4346	No
28	EIF2B1	EIF2B1 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa	4466	0.024	0.3892	No
29	MYO9B	MYO9B Entrez, Source	myosin IXB	4486	0.024	0.3907	No
30	NET1	NET1 Entrez, Source	neuroepithelial cell transforming gene 1	5025	0.015	0.3521	No
31	RASA3	RASA3 Entrez, Source	RAS p21 protein activator 3	5066	0.014	0.3508	No
32	RASGRP4	RASGRP4 Entrez, Source	RAS guanyl releasing protein 4	5408	0.009	0.3262	No
33	RIMS1	RIMS1 Entrez, Source	regulating synaptic membrane exocytosis 1	5444	0.008	0.3246	No
34	ARHGAP4	ARHGAP4 Entrez, Source	Rho GTPase activating protein 4	5575	0.006	0.3156	No
35	FGD1	FGD1 Entrez, Source	FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia)	5692	0.004	0.3074	No
36	CHN2	CHN2 Entrez, Source	chimerin (chimaerin) 2	5842	0.002	0.2964	No
37	RASA2	RASA2 Entrez, Source	RAS p21 protein activator 2	6217	-0.003	0.2687	No
38	ARHGEF11	ARHGEF11 Entrez, Source	Rho guanine nucleotide exchange factor (GEF) 11	6256	-0.004	0.2663	No
39	GPS1	GPS1 Entrez, Source	G protein pathway suppressor 1	6668	-0.010	0.2366	No
40	RGS6	RGS6 Entrez, Source	regulator of G-protein signalling 6	6832	-0.013	0.2259	No
41	RGS12	RGS12 Entrez, Source	regulator of G-protein signalling 12	6916	-0.014	0.2214	No
42	MADD	MADD Entrez, Source	MAP-kinase activating death domain	7149	-0.017	0.2061	No
43	KALRN	KALRN Entrez, Source	kalirin, RhoGEF kinase	7276	-0.019	0.1991	No
44	RGS9	RGS9 Entrez, Source	regulator of G-protein signalling 9	7456	-0.022	0.1884	No
45	CENTD2	CENTD2 Entrez, Source	centaurin, delta 2	7725	-0.026	0.1715	No
46	GDI2	GDI2 Entrez, Source	GDP dissociation inhibitor 2	7776	-0.027	0.1711	No
47	EIF2B4	EIF2B4 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	7792	-0.027	0.1734	No
48	ARHGAP5	ARHGAP5 Entrez, Source	Rho GTPase activating protein 5	8103	-0.032	0.1541	No
49	ARHGEF2	ARHGEF2 Entrez, Source	rho/rac guanine nucleotide exchange factor (GEF) 2	8130	-0.033	0.1563	No
50	ALS2	ALS2 Entrez, Source	amyotrophic lateral sclerosis 2 (juvenile)	8397	-0.037	0.1410	No
51	ARHGAP27	ARHGAP27 Entrez, Source	Rho GTPase activating protein 27	8729	-0.043	0.1214	No
52	RAB3GAP2	RAB3GAP2 Entrez, Source	RAB3 GTPase activating protein subunit 2 (non-catalytic)	8768	-0.043	0.1240	No
53	TSC2	TSC2 Entrez, Source	tuberous sclerosis 2	8912	-0.046	0.1190	No
54	TIAM1	TIAM1 Entrez, Source	T-cell lymphoma invasion and metastasis 1	9112	-0.049	0.1102	No
55	DLC1	DLC1 Entrez, Source	deleted in liver cancer 1	9141	-0.050	0.1143	No
56	ARL2BP	ARL2BP Entrez, Source	ADP-ribosylation factor-like 2 binding protein	9323	-0.053	0.1074	No
57	FGD4	FGD4 Entrez, Source	FYVE, RhoGEF and PH domain containing 4	10187	-0.070	0.0512	No
58	ARHGDIA	ARHGDIA Entrez, Source	Rho GDP dissociation inhibitor (GDI) alpha	10450	-0.076	0.0411	No
59	RANGAP1	RANGAP1 Entrez, Source	Ran GTPase activating protein 1	10603	-0.080	0.0397	No
60	NF1	NF1 Entrez, Source	neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)	10739	-0.084	0.0401	No
61	EIF2B3	EIF2B3 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	11098	-0.093	0.0249	No
62	RCBTB2	RCBTB2 Entrez, Source	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	11303	-0.099	0.0220	No
63	SIPA1	SIPA1 Entrez, Source	signal-induced proliferation-associated gene 1	11380	-0.101	0.0290	No
64	THY1	THY1 Entrez, Source	Thy-1 cell surface antigen	11400	-0.102	0.0404	No
65	RGS14	RGS14 Entrez, Source	regulator of G-protein signalling 14	11575	-0.108	0.0410	No
66	ARL2	ARL2 Entrez, Source	ADP-ribosylation factor-like 2	12040	-0.128	0.0222	No
67	RASA1	RASA1 Entrez, Source	RAS p21 protein activator (GTPase activating protein) 1	12457	-0.152	0.0100	No
68	EIF2B5	EIF2B5 Entrez, Source	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	12669	-0.170	0.0155	No
69	TRIO	TRIO Entrez, Source	triple functional domain (PTPRF interacting)	13166	-0.279	0.0133	No