Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HDACI_COLON_BUT48HRS_UP |
| Enrichment Score (ES) | 0.5419734 |
| Normalized Enrichment Score (NES) | 1.783648 |
| Nominal p-value | 0.0035842294 |
| FDR q-value | 0.028582623 |
| FWER p-Value | 0.98 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 9 | 0.936 | 0.1396 | Yes |
| 2 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 56 | 0.628 | 0.2302 | Yes |
| 3 | GSTM2 | GSTM2 Entrez, Source | glutathione S-transferase M2 (muscle) | 114 | 0.485 | 0.2986 | Yes |
| 4 | ZSWIM6 | ZSWIM6 Entrez, Source | zinc finger, SWIM-type containing 6 | 320 | 0.292 | 0.3270 | Yes |
| 5 | RHBDF1 | RHBDF1 Entrez, Source | rhomboid 5 homolog 1 (Drosophila) | 431 | 0.250 | 0.3562 | Yes |
| 6 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 571 | 0.212 | 0.3775 | Yes |
| 7 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 616 | 0.203 | 0.4046 | Yes |
| 8 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 722 | 0.182 | 0.4240 | Yes |
| 9 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 759 | 0.176 | 0.4477 | Yes |
| 10 | CALCOCO1 | CALCOCO1 Entrez, Source | calcium binding and coiled-coil domain 1 | 771 | 0.174 | 0.4729 | Yes |
| 11 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 784 | 0.172 | 0.4979 | Yes |
| 12 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 1161 | 0.131 | 0.4893 | Yes |
| 13 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1191 | 0.129 | 0.5064 | Yes |
| 14 | PSCD1 | PSCD1 Entrez, Source | pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1) | 1237 | 0.125 | 0.5217 | Yes |
| 15 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.5383 | Yes |
| 16 | IL17RE | IL17RE Entrez, Source | interleukin 17 receptor E | 1457 | 0.110 | 0.5401 | Yes |
| 17 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 1663 | 0.099 | 0.5396 | Yes |
| 18 | PLAG1 | PLAG1 Entrez, Source | pleiomorphic adenoma gene 1 | 1816 | 0.092 | 0.5420 | Yes |
| 19 | GPR108 | GPR108 Entrez, Source | G protein-coupled receptor 108 | 2145 | 0.079 | 0.5292 | No |
| 20 | UXS1 | UXS1 Entrez, Source | UDP-glucuronate decarboxylase 1 | 2561 | 0.066 | 0.5078 | No |
| 21 | GRN | GRN Entrez, Source | granulin | 2581 | 0.065 | 0.5161 | No |
| 22 | PSAP | PSAP Entrez, Source | prosaposin (variant Gaucher disease and variant metachromatic leukodystrophy) | 2642 | 0.064 | 0.5212 | No |
| 23 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2722 | 0.062 | 0.5245 | No |
| 24 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 2792 | 0.060 | 0.5284 | No |
| 25 | CLU | CLU Entrez, Source | clusterin | 3739 | 0.038 | 0.4628 | No |
| 26 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 4084 | 0.031 | 0.4416 | No |
| 27 | EPHB6 | EPHB6 Entrez, Source | EPH receptor B6 | 4295 | 0.027 | 0.4299 | No |
| 28 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 4389 | 0.026 | 0.4268 | No |
| 29 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 4485 | 0.024 | 0.4232 | No |
| 30 | MAPRE3 | MAPRE3 Entrez, Source | microtubule-associated protein, RP/EB family, member 3 | 4509 | 0.023 | 0.4249 | No |
| 31 | PLCB4 | PLCB4 Entrez, Source | phospholipase C, beta 4 | 5055 | 0.014 | 0.3860 | No |
| 32 | AQP1 | AQP1 Entrez, Source | aquaporin 1 (Colton blood group) | 5400 | 0.009 | 0.3614 | No |
| 33 | ZBTB17 | ZBTB17 Entrez, Source | zinc finger and BTB domain containing 17 | 5813 | 0.003 | 0.3308 | No |
| 34 | FLOT1 | FLOT1 Entrez, Source | flotillin 1 | 5897 | 0.002 | 0.3248 | No |
| 35 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 5912 | 0.001 | 0.3240 | No |
| 36 | ATP6AP2 | ATP6AP2 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 2 | 5915 | 0.001 | 0.3240 | No |
| 37 | CRYL1 | CRYL1 Entrez, Source | crystallin, lambda 1 | 6010 | -0.000 | 0.3169 | No |
| 38 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 7101 | -0.017 | 0.2374 | No |
| 39 | DNM3 | DNM3 Entrez, Source | dynamin 3 | 7241 | -0.019 | 0.2298 | No |
| 40 | GNL1 | GNL1 Entrez, Source | guanine nucleotide binding protein-like 1 | 7550 | -0.023 | 0.2101 | No |
| 41 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 7748 | -0.027 | 0.1993 | No |
| 42 | C2 | C2 Entrez, Source | complement component 2 | 7795 | -0.027 | 0.1999 | No |
| 43 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 7930 | -0.030 | 0.1942 | No |
| 44 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 7989 | -0.031 | 0.1945 | No |
| 45 | YIPF4 | YIPF4 Entrez, Source | Yip1 domain family, member 4 | 8203 | -0.034 | 0.1835 | No |
| 46 | AP2A2 | AP2A2 Entrez, Source | adaptor-related protein complex 2, alpha 2 subunit | 9957 | -0.066 | 0.0614 | No |
| 47 | GLI3 | GLI3 Entrez, Source | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | 10439 | -0.076 | 0.0366 | No |
| 48 | PPM2C | PPM2C Entrez, Source | protein phosphatase 2C, magnesium-dependent, catalytic subunit | 10699 | -0.083 | 0.0295 | No |
| 49 | ZUBR1 | ZUBR1 Entrez, Source | zinc finger, UBR1 type 1 | 11012 | -0.091 | 0.0196 | No |
| 50 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11208 | -0.096 | 0.0193 | No |
| 51 | TSNAX | TSNAX Entrez, Source | translin-associated factor X | 11363 | -0.101 | 0.0228 | No |
| 52 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 11380 | -0.101 | 0.0368 | No |
| 53 | SEPT3 | SEPT3 Entrez, Source | septin 3 | 11411 | -0.103 | 0.0499 | No |
| 54 | SKAP2 | SKAP2 Entrez, Source | src kinase associated phosphoprotein 2 | 12042 | -0.128 | 0.0217 | No |
| 55 | A1BG | A1BG Entrez, Source | alpha-1-B glycoprotein | 13096 | -0.252 | -0.0198 | No |
| 56 | FNBP4 | FNBP4 Entrez, Source | formin binding protein 4 | 13108 | -0.255 | 0.0176 | No |
