Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HOHENKIRK_MONOCYTE_DEND_UP |
| Enrichment Score (ES) | 0.5207731 |
| Normalized Enrichment Score (NES) | 1.791808 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.027143944 |
| FWER p-Value | 0.974 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 10 | 0.885 | 0.0744 | Yes |
| 2 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 29 | 0.753 | 0.1370 | Yes |
| 3 | LPL | LPL Entrez, Source | lipoprotein lipase | 45 | 0.671 | 0.1928 | Yes |
| 4 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 116 | 0.483 | 0.2286 | Yes |
| 5 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 151 | 0.445 | 0.2638 | Yes |
| 6 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 163 | 0.430 | 0.2995 | Yes |
| 7 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 187 | 0.400 | 0.3317 | Yes |
| 8 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 297 | 0.311 | 0.3499 | Yes |
| 9 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 313 | 0.297 | 0.3740 | Yes |
| 10 | GDF15 | GDF15 Entrez, Source | growth differentiation factor 15 | 385 | 0.267 | 0.3913 | Yes |
| 11 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 470 | 0.238 | 0.4051 | Yes |
| 12 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 472 | 0.237 | 0.4252 | Yes |
| 13 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 510 | 0.224 | 0.4414 | Yes |
| 14 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 533 | 0.219 | 0.4583 | Yes |
| 15 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 620 | 0.203 | 0.4691 | Yes |
| 16 | CYB5A | CYB5A Entrez, Source | cytochrome b5 type A (microsomal) | 817 | 0.167 | 0.4685 | Yes |
| 17 | ACOT2 | ACOT2 Entrez, Source | acyl-CoA thioesterase 2 | 876 | 0.159 | 0.4776 | Yes |
| 18 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 883 | 0.158 | 0.4906 | Yes |
| 19 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 884 | 0.158 | 0.5040 | Yes |
| 20 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 984 | 0.148 | 0.5091 | Yes |
| 21 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 1132 | 0.134 | 0.5094 | Yes |
| 22 | RNASE6 | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 1246 | 0.124 | 0.5114 | Yes |
| 23 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.5208 | Yes |
| 24 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 1650 | 0.100 | 0.5000 | No |
| 25 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 1720 | 0.096 | 0.5030 | No |
| 26 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 1723 | 0.096 | 0.5110 | No |
| 27 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.5151 | No |
| 28 | ACOT7 | ACOT7 Entrez, Source | acyl-CoA thioesterase 7 | 1811 | 0.092 | 0.5204 | No |
| 29 | ST6GAL1 | ST6GAL1 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 2013 | 0.085 | 0.5124 | No |
| 30 | AES | AES Entrez, Source | amino-terminal enhancer of split | 2144 | 0.079 | 0.5093 | No |
| 31 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 2395 | 0.071 | 0.4965 | No |
| 32 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 2430 | 0.070 | 0.4998 | No |
| 33 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 2803 | 0.060 | 0.4769 | No |
| 34 | C1QB | C1QB Entrez, Source | complement component 1, q subcomponent, B chain | 3017 | 0.054 | 0.4654 | No |
| 35 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 3215 | 0.049 | 0.4547 | No |
| 36 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3285 | 0.048 | 0.4536 | No |
| 37 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 3296 | 0.047 | 0.4568 | No |
| 38 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 3333 | 0.046 | 0.4581 | No |
| 39 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 3417 | 0.045 | 0.4556 | No |
| 40 | RAP1GAP | RAP1GAP Entrez, Source | RAP1 GTPase activating protein | 3624 | 0.040 | 0.4435 | No |
| 41 | ECM1 | ECM1 Entrez, Source | extracellular matrix protein 1 | 3867 | 0.035 | 0.4282 | No |
| 42 | PTPRO | PTPRO Entrez, Source | protein tyrosine phosphatase, receptor type, O | 3944 | 0.034 | 0.4254 | No |
| 43 | ARF4 | ARF4 Entrez, Source | ADP-ribosylation factor 4 | 4231 | 0.029 | 0.4063 | No |
| 44 | INHBA | INHBA Entrez, Source | inhibin, beta A (activin A, activin AB alpha polypeptide) | 5081 | 0.014 | 0.3434 | No |
| 45 | HMGN3 | HMGN3 Entrez, Source | high mobility group nucleosomal binding domain 3 | 5116 | 0.013 | 0.3419 | No |
| 46 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 5350 | 0.009 | 0.3252 | No |
| 47 | CCL17 | CCL17 Entrez, Source | chemokine (C-C motif) ligand 17 | 5384 | 0.009 | 0.3234 | No |
| 48 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 5738 | 0.004 | 0.2971 | No |
| 49 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 5751 | 0.003 | 0.2965 | No |
| 50 | CCL22 | CCL22 Entrez, Source | chemokine (C-C motif) ligand 22 | 6089 | -0.001 | 0.2712 | No |
| 51 | CD86 | CD86 Entrez, Source | CD86 molecule | 6302 | -0.005 | 0.2556 | No |
| 52 | CAT | CAT Entrez, Source | catalase | 6311 | -0.005 | 0.2555 | No |
| 53 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 6879 | -0.013 | 0.2138 | No |
| 54 | SLA | SLA Entrez, Source | Src-like-adaptor | 7587 | -0.024 | 0.1625 | No |
| 55 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 7612 | -0.024 | 0.1628 | No |
| 56 | PCBD1 | PCBD1 Entrez, Source | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) | 7839 | -0.028 | 0.1481 | No |
| 57 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 7929 | -0.030 | 0.1439 | No |
| 58 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 8086 | -0.032 | 0.1349 | No |
| 59 | DNASE1L3 | DNASE1L3 Entrez, Source | deoxyribonuclease I-like 3 | 8386 | -0.037 | 0.1155 | No |
| 60 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 8634 | -0.041 | 0.1003 | No |
| 61 | ALOX15 | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 8665 | -0.041 | 0.1016 | No |
| 62 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8856 | -0.045 | 0.0911 | No |
| 63 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 8984 | -0.047 | 0.0855 | No |
| 64 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 9094 | -0.049 | 0.0814 | No |
| 65 | KCNAB2 | KCNAB2 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 9157 | -0.050 | 0.0810 | No |
| 66 | PEBP1 | PEBP1 Entrez, Source | phosphatidylethanolamine binding protein 1 | 9244 | -0.051 | 0.0789 | No |
| 67 | CTSC | CTSC Entrez, Source | cathepsin C | 9429 | -0.055 | 0.0696 | No |
| 68 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 9459 | -0.055 | 0.0721 | No |
| 69 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 9836 | -0.063 | 0.0491 | No |
| 70 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 9946 | -0.065 | 0.0465 | No |
| 71 | CCNH | CCNH Entrez, Source | cyclin H | 10928 | -0.089 | -0.0200 | No |
| 72 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 11720 | -0.114 | -0.0700 | No |
| 73 | A2M | A2M Entrez, Source | alpha-2-macroglobulin | 12069 | -0.130 | -0.0852 | No |
| 74 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 12121 | -0.133 | -0.0778 | No |
| 75 | FCGR2B | FCGR2B Entrez, Source | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 12366 | -0.147 | -0.0837 | No |
| 76 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 12368 | -0.147 | -0.0713 | No |
| 77 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 12653 | -0.168 | -0.0784 | No |
| 78 | SULT1C1 | SULT1C1 Entrez, Source | sulfotransferase family, cytosolic, 1C, member 1 | 12806 | -0.186 | -0.0741 | No |
| 79 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 12923 | -0.203 | -0.0656 | No |
| 80 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 13029 | -0.225 | -0.0544 | No |
| 81 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 13197 | -0.299 | -0.0416 | No |
| 82 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13325 | -0.617 | 0.0013 | No |
