Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00010_GLYCOLYSIS_AND_GLUCONEOGENESIS |
| Enrichment Score (ES) | 0.60375285 |
| Normalized Enrichment Score (NES) | 1.9144696 |
| Nominal p-value | 0.001754386 |
| FDR q-value | 0.010836435 |
| FWER p-Value | 0.544 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 22 | 0.785 | 0.1319 | Yes |
| 2 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 29 | 0.753 | 0.2596 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 57 | 0.628 | 0.3644 | Yes |
| 4 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 74 | 0.567 | 0.4597 | Yes |
| 5 | HK1 | HK1 Entrez, Source | hexokinase 1 | 251 | 0.342 | 0.5047 | Yes |
| 6 | DLAT | DLAT Entrez, Source | dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) | 444 | 0.246 | 0.5322 | Yes |
| 7 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 517 | 0.223 | 0.5648 | Yes |
| 8 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 720 | 0.182 | 0.5806 | Yes |
| 9 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 798 | 0.170 | 0.6038 | Yes |
| 10 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 1564 | 0.104 | 0.5640 | No |
| 11 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 1624 | 0.101 | 0.5768 | No |
| 12 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 1980 | 0.086 | 0.5647 | No |
| 13 | HK2 | HK2 Entrez, Source | hexokinase 2 | 2661 | 0.063 | 0.5243 | No |
| 14 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 3072 | 0.052 | 0.5024 | No |
| 15 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 3169 | 0.050 | 0.5037 | No |
| 16 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 3245 | 0.048 | 0.5063 | No |
| 17 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 3253 | 0.048 | 0.5140 | No |
| 18 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 3254 | 0.048 | 0.5222 | No |
| 19 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 3287 | 0.048 | 0.5279 | No |
| 20 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 3365 | 0.046 | 0.5299 | No |
| 21 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 3467 | 0.044 | 0.5298 | No |
| 22 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 3480 | 0.043 | 0.5363 | No |
| 23 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 3592 | 0.041 | 0.5349 | No |
| 24 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 3672 | 0.039 | 0.5356 | No |
| 25 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 3755 | 0.037 | 0.5358 | No |
| 26 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 4344 | 0.026 | 0.4961 | No |
| 27 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 4805 | 0.018 | 0.4646 | No |
| 28 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 5074 | 0.014 | 0.4468 | No |
| 29 | GALM | GALM Entrez, Source | galactose mutarotase (aldose 1-epimerase) | 5498 | 0.007 | 0.4163 | No |
| 30 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 5536 | 0.007 | 0.4147 | No |
| 31 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 5738 | 0.004 | 0.4002 | No |
| 32 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 5740 | 0.004 | 0.4007 | No |
| 33 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 6030 | -0.000 | 0.3790 | No |
| 34 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6171 | -0.003 | 0.3689 | No |
| 35 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 6473 | -0.007 | 0.3475 | No |
| 36 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 6931 | -0.014 | 0.3155 | No |
| 37 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 7146 | -0.017 | 0.3024 | No |
| 38 | PGAM1 | PGAM1 Entrez, Source | phosphoglycerate mutase 1 (brain) | 7875 | -0.029 | 0.2525 | No |
| 39 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 8467 | -0.038 | 0.2146 | No |
| 40 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 8536 | -0.039 | 0.2162 | No |
| 41 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 9409 | -0.054 | 0.1599 | No |
| 42 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 9489 | -0.056 | 0.1634 | No |
| 43 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 9804 | -0.062 | 0.1504 | No |
| 44 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9880 | -0.064 | 0.1556 | No |
| 45 | LDHAL6B | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 11134 | -0.094 | 0.0774 | No |
| 46 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 13114 | -0.257 | -0.0277 | No |
| 47 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 13135 | -0.263 | 0.0156 | No |
