Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA00640_PROPANOATE_METABOLISM |
| Enrichment Score (ES) | 0.63492614 |
| Normalized Enrichment Score (NES) | 1.7699713 |
| Nominal p-value | 0.001934236 |
| FDR q-value | 0.030662306 |
| FWER p-Value | 0.987 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 22 | 0.785 | 0.2788 | Yes |
| 2 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 517 | 0.223 | 0.3216 | Yes |
| 3 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 585 | 0.209 | 0.3911 | Yes |
| 4 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 713 | 0.183 | 0.4469 | Yes |
| 5 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 798 | 0.170 | 0.5013 | Yes |
| 6 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 809 | 0.168 | 0.5607 | Yes |
| 7 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 826 | 0.166 | 0.6187 | Yes |
| 8 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 1585 | 0.103 | 0.5987 | Yes |
| 9 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1594 | 0.103 | 0.6349 | Yes |
| 10 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 2882 | 0.058 | 0.5590 | No |
| 11 | PCCB | PCCB Entrez, Source | propionyl Coenzyme A carboxylase, beta polypeptide | 2977 | 0.055 | 0.5717 | No |
| 12 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 3245 | 0.048 | 0.5689 | No |
| 13 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 3480 | 0.043 | 0.5668 | No |
| 14 | ALDH7A1 | ALDH7A1 Entrez, Source | aldehyde dehydrogenase 7 family, member A1 | 3592 | 0.041 | 0.5731 | No |
| 15 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 3672 | 0.039 | 0.5813 | No |
| 16 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4941 | 0.016 | 0.4918 | No |
| 17 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 5536 | 0.007 | 0.4496 | No |
| 18 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 5593 | 0.006 | 0.4475 | No |
| 19 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 5939 | 0.001 | 0.4220 | No |
| 20 | HIBCH | HIBCH Entrez, Source | 3-hydroxyisobutyryl-Coenzyme A hydrolase | 6051 | -0.001 | 0.4139 | No |
| 21 | ACACB | ACACB Entrez, Source | acetyl-Coenzyme A carboxylase beta | 6400 | -0.006 | 0.3900 | No |
| 22 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 7326 | -0.020 | 0.3277 | No |
| 23 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 8536 | -0.039 | 0.2510 | No |
| 24 | LDHAL6B | LDHAL6B Entrez, Source | lactate dehydrogenase A-like 6B | 11134 | -0.094 | 0.0896 | No |
| 25 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 12971 | -0.213 | 0.0279 | No |
