Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA01430_CELL_COMMUNICATION |
| Enrichment Score (ES) | 0.7269894 |
| Normalized Enrichment Score (NES) | 2.3054736 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 4 | 1.225 | 0.1254 | Yes |
| 2 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 6 | 1.154 | 0.2437 | Yes |
| 3 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 19 | 0.791 | 0.3239 | Yes |
| 4 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 21 | 0.785 | 0.4044 | Yes |
| 5 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 34 | 0.714 | 0.4767 | Yes |
| 6 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 58 | 0.625 | 0.5391 | Yes |
| 7 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 165 | 0.429 | 0.5751 | Yes |
| 8 | GJA1 | GJA1 Entrez, Source | gap junction protein, alpha 1, 43kDa (connexin 43) | 173 | 0.414 | 0.6171 | Yes |
| 9 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 252 | 0.342 | 0.6462 | Yes |
| 10 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 433 | 0.249 | 0.6583 | Yes |
| 11 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 475 | 0.236 | 0.6794 | Yes |
| 12 | GJB5 | GJB5 Entrez, Source | gap junction protein, beta 5 (connexin 31.1) | 534 | 0.219 | 0.6975 | Yes |
| 13 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 658 | 0.195 | 0.7083 | Yes |
| 14 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 673 | 0.190 | 0.7268 | Yes |
| 15 | KRT25 | KRT25 Entrez, Source | keratin 25 | 1097 | 0.137 | 0.7090 | Yes |
| 16 | NES | NES Entrez, Source | nestin | 1147 | 0.132 | 0.7189 | Yes |
| 17 | VTN | VTN Entrez, Source | vitronectin | 1239 | 0.124 | 0.7248 | Yes |
| 18 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 1466 | 0.110 | 0.7190 | Yes |
| 19 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 1749 | 0.095 | 0.7076 | Yes |
| 20 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.7153 | Yes |
| 21 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 1802 | 0.093 | 0.7229 | Yes |
| 22 | GJB1 | GJB1 Entrez, Source | gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked) | 1871 | 0.090 | 0.7270 | Yes |
| 23 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 2660 | 0.063 | 0.6742 | No |
| 24 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2715 | 0.062 | 0.6765 | No |
| 25 | DES | DES Entrez, Source | desmin | 2879 | 0.058 | 0.6702 | No |
| 26 | RELN | RELN Entrez, Source | reelin | 3719 | 0.038 | 0.6111 | No |
| 27 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 4300 | 0.027 | 0.5702 | No |
| 28 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4726 | 0.020 | 0.5403 | No |
| 29 | ACTB | ACTB Entrez, Source | actin, beta | 5041 | 0.014 | 0.5181 | No |
| 30 | KRT20 | KRT20 Entrez, Source | keratin 20 | 5561 | 0.006 | 0.4798 | No |
| 31 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 5644 | 0.005 | 0.4741 | No |
| 32 | LMNA | LMNA Entrez, Source | lamin A/C | 6342 | -0.005 | 0.4222 | No |
| 33 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6731 | -0.011 | 0.3942 | No |
| 34 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 6734 | -0.011 | 0.3952 | No |
| 35 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 6909 | -0.014 | 0.3835 | No |
| 36 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 7019 | -0.015 | 0.3769 | No |
| 37 | GJB4 | GJB4 Entrez, Source | gap junction protein, beta 4 (connexin 30.3) | 7942 | -0.030 | 0.3106 | No |
| 38 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 8125 | -0.033 | 0.3002 | No |
| 39 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 8230 | -0.034 | 0.2960 | No |
| 40 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 8277 | -0.035 | 0.2961 | No |
| 41 | VWF | VWF Entrez, Source | von Willebrand factor | 8376 | -0.037 | 0.2925 | No |
| 42 | GJA3 | GJA3 Entrez, Source | gap junction protein, alpha 3, 46kDa (connexin 46) | 9083 | -0.049 | 0.2444 | No |
| 43 | CHAD | CHAD Entrez, Source | chondroadherin | 9330 | -0.053 | 0.2314 | No |
| 44 | GJB6 | GJB6 Entrez, Source | gap junction protein, beta 6 (connexin 30) | 10353 | -0.074 | 0.1620 | No |
| 45 | GJA5 | GJA5 Entrez, Source | gap junction protein, alpha 5, 40kDa (connexin 40) | 10784 | -0.085 | 0.1384 | No |
| 46 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11330 | -0.100 | 0.1076 | No |
| 47 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 11513 | -0.106 | 0.1048 | No |
| 48 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 12502 | -0.155 | 0.0464 | No |
| 49 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 12600 | -0.163 | 0.0558 | No |
