Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA03320_PPAR_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.59017634 |
| Normalized Enrichment Score (NES) | 1.9332647 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008871616 |
| FWER p-Value | 0.454 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP8B1 | CYP8B1 Entrez, Source | cytochrome P450, family 8, subfamily B, polypeptide 1 | 23 | 0.784 | 0.0773 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 35 | 0.711 | 0.1482 | Yes |
| 3 | LPL | LPL Entrez, Source | lipoprotein lipase | 45 | 0.671 | 0.2152 | Yes |
| 4 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 47 | 0.660 | 0.2817 | Yes |
| 5 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 83 | 0.552 | 0.3347 | Yes |
| 6 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 121 | 0.476 | 0.3800 | Yes |
| 7 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 351 | 0.281 | 0.3910 | Yes |
| 8 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 379 | 0.269 | 0.4161 | Yes |
| 9 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 394 | 0.263 | 0.4416 | Yes |
| 10 | ANGPTL4 | ANGPTL4 Entrez, Source | angiopoietin-like 4 | 493 | 0.230 | 0.4574 | Yes |
| 11 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 548 | 0.217 | 0.4752 | Yes |
| 12 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 580 | 0.210 | 0.4940 | Yes |
| 13 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 726 | 0.181 | 0.5014 | Yes |
| 14 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 826 | 0.166 | 0.5106 | Yes |
| 15 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 884 | 0.158 | 0.5223 | Yes |
| 16 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 976 | 0.149 | 0.5304 | Yes |
| 17 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 984 | 0.148 | 0.5449 | Yes |
| 18 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 1026 | 0.144 | 0.5563 | Yes |
| 19 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 1086 | 0.137 | 0.5657 | Yes |
| 20 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 1096 | 0.137 | 0.5788 | Yes |
| 21 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1126 | 0.134 | 0.5902 | Yes |
| 22 | SLC27A1 | SLC27A1 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 1 | 1356 | 0.116 | 0.5846 | No |
| 23 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 1567 | 0.104 | 0.5793 | No |
| 24 | APOA2 | APOA2 Entrez, Source | apolipoprotein A-II | 1596 | 0.103 | 0.5876 | No |
| 25 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 1854 | 0.090 | 0.5774 | No |
| 26 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 1886 | 0.089 | 0.5840 | No |
| 27 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 2355 | 0.072 | 0.5561 | No |
| 28 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 2591 | 0.065 | 0.5450 | No |
| 29 | ACSL6 | ACSL6 Entrez, Source | acyl-CoA synthetase long-chain family member 6 | 2697 | 0.063 | 0.5434 | No |
| 30 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 2738 | 0.062 | 0.5466 | No |
| 31 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 2902 | 0.057 | 0.5401 | No |
| 32 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 3172 | 0.050 | 0.5249 | No |
| 33 | CPT1C | CPT1C Entrez, Source | carnitine palmitoyltransferase 1C | 3425 | 0.045 | 0.5104 | No |
| 34 | SLC27A4 | SLC27A4 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 4 | 3783 | 0.037 | 0.4873 | No |
| 35 | ILK | ILK Entrez, Source | integrin-linked kinase | 3923 | 0.034 | 0.4803 | No |
| 36 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4941 | 0.016 | 0.4054 | No |
| 37 | UBC | UBC Entrez, Source | ubiquitin C | 4954 | 0.016 | 0.4061 | No |
| 38 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 6090 | -0.001 | 0.3208 | No |
| 39 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 6137 | -0.002 | 0.3175 | No |
| 40 | PDPK1 | PDPK1 Entrez, Source | 3-phosphoinositide dependent protein kinase-1 | 6739 | -0.011 | 0.2735 | No |
| 41 | PLIN | PLIN Entrez, Source | perilipin | 6998 | -0.015 | 0.2556 | No |
| 42 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 7396 | -0.021 | 0.2278 | No |
| 43 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 7930 | -0.030 | 0.1906 | No |
| 44 | FABP6 | FABP6 Entrez, Source | fatty acid binding protein 6, ileal (gastrotropin) | 8416 | -0.038 | 0.1579 | No |
| 45 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 9075 | -0.048 | 0.1133 | No |
| 46 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 9436 | -0.055 | 0.0917 | No |
| 47 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 9459 | -0.055 | 0.0957 | No |
| 48 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 9649 | -0.059 | 0.0874 | No |
| 49 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 11075 | -0.092 | -0.0106 | No |
| 50 | UCP1 | UCP1 Entrez, Source | uncoupling protein 1 (mitochondrial, proton carrier) | 11284 | -0.098 | -0.0163 | No |
| 51 | FABP5 | FABP5 Entrez, Source | fatty acid binding protein 5 (psoriasis-associated) | 12121 | -0.133 | -0.0659 | No |
| 52 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 12287 | -0.141 | -0.0640 | No |
| 53 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 12809 | -0.187 | -0.0844 | No |
| 54 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 13297 | -0.441 | -0.0766 | No |
| 55 | FABP7 | FABP7 Entrez, Source | fatty acid binding protein 7, brain | 13332 | -0.793 | 0.0008 | No |
