Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HSA04512_ECM_RECEPTOR_INTERACTION |
| Enrichment Score (ES) | 0.63721293 |
| Normalized Enrichment Score (NES) | 2.083327 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0015141673 |
| FWER p-Value | 0.045 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 6 | 1.154 | 0.1407 | Yes |
| 2 | LAMC2 | LAMC2 Entrez, Source | laminin, gamma 2 | 19 | 0.791 | 0.2366 | Yes |
| 3 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 21 | 0.785 | 0.3326 | Yes |
| 4 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 34 | 0.714 | 0.4191 | Yes |
| 5 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 58 | 0.625 | 0.4938 | Yes |
| 6 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 165 | 0.429 | 0.5383 | Yes |
| 7 | LAMC1 | LAMC1 Entrez, Source | laminin, gamma 1 (formerly LAMB2) | 252 | 0.342 | 0.5736 | Yes |
| 8 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 433 | 0.249 | 0.5906 | Yes |
| 9 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 658 | 0.195 | 0.5976 | Yes |
| 10 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 673 | 0.190 | 0.6199 | Yes |
| 11 | ITGA9 | ITGA9 Entrez, Source | integrin, alpha 9 | 767 | 0.175 | 0.6342 | Yes |
| 12 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 1054 | 0.141 | 0.6300 | Yes |
| 13 | VTN | VTN Entrez, Source | vitronectin | 1239 | 0.124 | 0.6313 | Yes |
| 14 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 1466 | 0.110 | 0.6278 | Yes |
| 15 | COL11A1 | COL11A1 Entrez, Source | collagen, type XI, alpha 1 | 1749 | 0.095 | 0.6182 | Yes |
| 16 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.6278 | Yes |
| 17 | COL4A4 | COL4A4 Entrez, Source | collagen, type IV, alpha 4 | 1802 | 0.093 | 0.6372 | Yes |
| 18 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 2059 | 0.083 | 0.6281 | No |
| 19 | DAG1 | DAG1 Entrez, Source | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 2610 | 0.065 | 0.5946 | No |
| 20 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 2660 | 0.063 | 0.5987 | No |
| 21 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2715 | 0.062 | 0.6023 | No |
| 22 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3385 | 0.045 | 0.5575 | No |
| 23 | CD47 | CD47 Entrez, Source | CD47 molecule | 3700 | 0.039 | 0.5386 | No |
| 24 | RELN | RELN Entrez, Source | reelin | 3719 | 0.038 | 0.5419 | No |
| 25 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 3845 | 0.036 | 0.5369 | No |
| 26 | FNDC1 | FNDC1 Entrez, Source | fibronectin type III domain containing 1 | 4271 | 0.028 | 0.5083 | No |
| 27 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 4300 | 0.027 | 0.5096 | No |
| 28 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 4705 | 0.020 | 0.4816 | No |
| 29 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4726 | 0.020 | 0.4825 | No |
| 30 | SV2C | SV2C Entrez, Source | synaptic vesicle glycoprotein 2C | 5594 | 0.006 | 0.4180 | No |
| 31 | SV2B | SV2B Entrez, Source | synaptic vesicle glycoprotein 2B | 6189 | -0.003 | 0.3737 | No |
| 32 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6731 | -0.011 | 0.3343 | No |
| 33 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 6774 | -0.012 | 0.3326 | No |
| 34 | IBSP | IBSP Entrez, Source | integrin-binding sialoprotein (bone sialoprotein, bone sialoprotein II) | 7019 | -0.015 | 0.3161 | No |
| 35 | TNR | TNR Entrez, Source | tenascin R (restrictin, janusin) | 8230 | -0.034 | 0.2293 | No |
| 36 | THBS4 | THBS4 Entrez, Source | thrombospondin 4 | 8277 | -0.035 | 0.2302 | No |
| 37 | GP5 | GP5 Entrez, Source | glycoprotein V (platelet) | 8293 | -0.036 | 0.2334 | No |
| 38 | VWF | VWF Entrez, Source | von Willebrand factor | 8376 | -0.037 | 0.2318 | No |
| 39 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 8872 | -0.045 | 0.2001 | No |
| 40 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 8914 | -0.046 | 0.2026 | No |
| 41 | FNDC5 | FNDC5 Entrez, Source | fibronectin type III domain containing 5 | 8963 | -0.047 | 0.2047 | No |
| 42 | SDC3 | SDC3 Entrez, Source | syndecan 3 (N-syndecan) | 9311 | -0.053 | 0.1850 | No |
| 43 | CHAD | CHAD Entrez, Source | chondroadherin | 9330 | -0.053 | 0.1902 | No |
| 44 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 9725 | -0.061 | 0.1679 | No |
| 45 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 9876 | -0.064 | 0.1645 | No |
| 46 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 9946 | -0.065 | 0.1673 | No |
| 47 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 11513 | -0.106 | 0.0624 | No |
| 48 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 11584 | -0.109 | 0.0705 | No |
| 49 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 12502 | -0.155 | 0.0204 | No |
| 50 | LAMB3 | LAMB3 Entrez, Source | laminin, beta 3 | 12600 | -0.163 | 0.0331 | No |
| 51 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12802 | -0.185 | 0.0406 | No |
