Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | HYPOPHYSECTOMY_RAT_DN |
| Enrichment Score (ES) | 0.62735575 |
| Normalized Enrichment Score (NES) | 1.9714673 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0059097833 |
| FWER p-Value | 0.286 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 21 | 0.785 | 0.1407 | Yes |
| 2 | MGP | MGP Entrez, Source | matrix Gla protein | 52 | 0.634 | 0.2533 | Yes |
| 3 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 84 | 0.549 | 0.3504 | Yes |
| 4 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 181 | 0.405 | 0.4167 | Yes |
| 5 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 317 | 0.293 | 0.4597 | Yes |
| 6 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 378 | 0.269 | 0.5039 | Yes |
| 7 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 470 | 0.238 | 0.5401 | Yes |
| 8 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 566 | 0.213 | 0.5715 | Yes |
| 9 | PIM3 | PIM3 Entrez, Source | pim-3 oncogene | 678 | 0.189 | 0.5974 | Yes |
| 10 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 720 | 0.182 | 0.6274 | Yes |
| 11 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 1854 | 0.090 | 0.5585 | No |
| 12 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1962 | 0.087 | 0.5662 | No |
| 13 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 2355 | 0.072 | 0.5498 | No |
| 14 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 2700 | 0.063 | 0.5352 | No |
| 15 | FN1 | FN1 Entrez, Source | fibronectin 1 | 2715 | 0.062 | 0.5455 | No |
| 16 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 3253 | 0.048 | 0.5138 | No |
| 17 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3357 | 0.046 | 0.5144 | No |
| 18 | DCN | DCN Entrez, Source | decorin | 3405 | 0.045 | 0.5190 | No |
| 19 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 3902 | 0.035 | 0.4880 | No |
| 20 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 3918 | 0.034 | 0.4931 | No |
| 21 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 3981 | 0.033 | 0.4945 | No |
| 22 | RAB3B | RAB3B Entrez, Source | RAB3B, member RAS oncogene family | 4139 | 0.030 | 0.4881 | No |
| 23 | ARF4 | ARF4 Entrez, Source | ADP-ribosylation factor 4 | 4231 | 0.029 | 0.4865 | No |
| 24 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 4552 | 0.022 | 0.4665 | No |
| 25 | MEP1B | MEP1B Entrez, Source | meprin A, beta | 4999 | 0.015 | 0.4357 | No |
| 26 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 5059 | 0.014 | 0.4338 | No |
| 27 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 5182 | 0.012 | 0.4268 | No |
| 28 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 5350 | 0.009 | 0.4159 | No |
| 29 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 5480 | 0.008 | 0.4076 | No |
| 30 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 5536 | 0.007 | 0.4047 | No |
| 31 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 5564 | 0.006 | 0.4038 | No |
| 32 | NPPA | NPPA Entrez, Source | natriuretic peptide precursor A | 5715 | 0.004 | 0.3933 | No |
| 33 | B2M | B2M Entrez, Source | beta-2-microglobulin | 5795 | 0.003 | 0.3878 | No |
| 34 | FTH1 | FTH1 Entrez, Source | ferritin, heavy polypeptide 1 | 6933 | -0.014 | 0.3049 | No |
| 35 | PEX19 | PEX19 Entrez, Source | peroxisomal biogenesis factor 19 | 7061 | -0.016 | 0.2982 | No |
| 36 | ATP2A2 | ATP2A2 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 7943 | -0.030 | 0.2374 | No |
| 37 | FBLN5 | FBLN5 Entrez, Source | fibulin 5 | 8019 | -0.031 | 0.2374 | No |
| 38 | CALR | CALR Entrez, Source | calreticulin | 9052 | -0.048 | 0.1685 | No |
| 39 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 9115 | -0.049 | 0.1727 | No |
| 40 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 9119 | -0.049 | 0.1814 | No |
| 41 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 9489 | -0.056 | 0.1638 | No |
| 42 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 10749 | -0.084 | 0.0843 | No |
| 43 | TKT | TKT Entrez, Source | transketolase (Wernicke-Korsakoff syndrome) | 11381 | -0.101 | 0.0552 | No |
| 44 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 11422 | -0.103 | 0.0709 | No |
| 45 | LIMS2 | LIMS2 Entrez, Source | LIM and senescent cell antigen-like domains 2 | 12127 | -0.133 | 0.0420 | No |
| 46 | PSMB8 | PSMB8 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 13154 | -0.272 | 0.0141 | No |
