Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IDX_TSA_DN_CLUSTER2 |
| Enrichment Score (ES) | 0.57685673 |
| Normalized Enrichment Score (NES) | 1.8370637 |
| Nominal p-value | 0.0017921147 |
| FDR q-value | 0.02012364 |
| FWER p-Value | 0.886 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 142 | 0.455 | 0.0634 | Yes |
| 2 | LOX | LOX Entrez, Source | lysyl oxidase | 154 | 0.441 | 0.1344 | Yes |
| 3 | PGCP | PGCP Entrez, Source | - | 183 | 0.404 | 0.1980 | Yes |
| 4 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 237 | 0.355 | 0.2517 | Yes |
| 5 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 273 | 0.325 | 0.3019 | Yes |
| 6 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 498 | 0.228 | 0.3221 | Yes |
| 7 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 516 | 0.223 | 0.3572 | Yes |
| 8 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 639 | 0.199 | 0.3804 | Yes |
| 9 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 670 | 0.192 | 0.4093 | Yes |
| 10 | CD276 | CD276 Entrez, Source | CD276 molecule | 683 | 0.188 | 0.4390 | Yes |
| 11 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 755 | 0.176 | 0.4623 | Yes |
| 12 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 795 | 0.170 | 0.4871 | Yes |
| 13 | PLD3 | PLD3 Entrez, Source | phospholipase D family, member 3 | 959 | 0.151 | 0.4993 | Yes |
| 14 | PDPN | PDPN Entrez, Source | podoplanin | 991 | 0.147 | 0.5210 | Yes |
| 15 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 1170 | 0.131 | 0.5289 | Yes |
| 16 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1191 | 0.129 | 0.5483 | Yes |
| 17 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 1310 | 0.119 | 0.5588 | Yes |
| 18 | TES | TES Entrez, Source | testis derived transcript (3 LIM domains) | 1616 | 0.102 | 0.5525 | Yes |
| 19 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 1684 | 0.098 | 0.5634 | Yes |
| 20 | LAMP2 | LAMP2 Entrez, Source | lysosomal-associated membrane protein 2 | 1744 | 0.095 | 0.5745 | Yes |
| 21 | SCPEP1 | SCPEP1 Entrez, Source | serine carboxypeptidase 1 | 2022 | 0.084 | 0.5673 | Yes |
| 22 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 2074 | 0.082 | 0.5769 | Yes |
| 23 | MAP1LC3B | MAP1LC3B Entrez, Source | microtubule-associated protein 1 light chain 3 beta | 2854 | 0.059 | 0.5278 | No |
| 24 | SERTAD1 | SERTAD1 Entrez, Source | SERTA domain containing 1 | 2936 | 0.057 | 0.5309 | No |
| 25 | MSN | MSN Entrez, Source | moesin | 3404 | 0.045 | 0.5031 | No |
| 26 | SLC38A4 | SLC38A4 Entrez, Source | solute carrier family 38, member 4 | 3436 | 0.044 | 0.5080 | No |
| 27 | LEPROT | LEPROT Entrez, Source | leptin receptor overlapping transcript | 3751 | 0.038 | 0.4905 | No |
| 28 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 4084 | 0.031 | 0.4706 | No |
| 29 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 4156 | 0.030 | 0.4702 | No |
| 30 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 4653 | 0.021 | 0.4363 | No |
| 31 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 4697 | 0.020 | 0.4363 | No |
| 32 | PPGB | PPGB Entrez, Source | protective protein for beta-galactosidase (galactosialidosis) | 5564 | 0.006 | 0.3722 | No |
| 33 | DSTN | DSTN Entrez, Source | destrin (actin depolymerizing factor) | 5815 | 0.003 | 0.3538 | No |
| 34 | SLC1A4 | SLC1A4 Entrez, Source | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 | 6096 | -0.002 | 0.3330 | No |
| 35 | PDLIM7 | PDLIM7 Entrez, Source | PDZ and LIM domain 7 (enigma) | 6732 | -0.011 | 0.2871 | No |
| 36 | NCAM1 | NCAM1 Entrez, Source | neural cell adhesion molecule 1 | 7426 | -0.021 | 0.2384 | No |
| 37 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 8646 | -0.041 | 0.1534 | No |
| 38 | TWIST2 | TWIST2 Entrez, Source | twist homolog 2 (Drosophila) | 9406 | -0.054 | 0.1052 | No |
| 39 | CD99 | CD99 Entrez, Source | CD99 molecule | 9921 | -0.065 | 0.0770 | No |
| 40 | PLXNB2 | PLXNB2 Entrez, Source | plexin B2 | 9951 | -0.066 | 0.0855 | No |
| 41 | TINP1 | TINP1 Entrez, Source | - | 10027 | -0.067 | 0.0907 | No |
| 42 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 10518 | -0.078 | 0.0666 | No |
| 43 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10615 | -0.080 | 0.0725 | No |
| 44 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 11636 | -0.111 | 0.0138 | No |
| 45 | GNB1 | GNB1 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 11712 | -0.114 | 0.0266 | No |
| 46 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 12255 | -0.140 | 0.0086 | No |
| 47 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 12402 | -0.149 | 0.0218 | No |
| 48 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 13201 | -0.300 | 0.0106 | No |
