Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | IFN_BETA_UP |
| Enrichment Score (ES) | -0.4246695 |
| Normalized Enrichment Score (NES) | -1.3937081 |
| Nominal p-value | 0.06369427 |
| FDR q-value | 0.35068756 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 566 | 0.213 | 0.0194 | No |
| 2 | AP3M2 | AP3M2 Entrez, Source | adaptor-related protein complex 3, mu 2 subunit | 889 | 0.157 | 0.0410 | No |
| 3 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 1221 | 0.126 | 0.0528 | No |
| 4 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 1274 | 0.122 | 0.0843 | No |
| 5 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 1691 | 0.098 | 0.0815 | No |
| 6 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 1977 | 0.086 | 0.0850 | No |
| 7 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2629 | 0.064 | 0.0547 | No |
| 8 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 2983 | 0.055 | 0.0442 | No |
| 9 | CTR9 | CTR9 Entrez, Source | Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 3465 | 0.044 | 0.0208 | No |
| 10 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3854 | 0.036 | 0.0019 | No |
| 11 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 4677 | 0.020 | -0.0539 | No |
| 12 | PPP5C | PPP5C Entrez, Source | protein phosphatase 5, catalytic subunit | 5131 | 0.013 | -0.0842 | No |
| 13 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 5231 | 0.011 | -0.0884 | No |
| 14 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 5583 | 0.006 | -0.1130 | No |
| 15 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 5682 | 0.005 | -0.1190 | No |
| 16 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 5970 | 0.001 | -0.1405 | No |
| 17 | CSRP3 | CSRP3 Entrez, Source | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 6009 | -0.000 | -0.1433 | No |
| 18 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 6173 | -0.003 | -0.1548 | No |
| 19 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 6362 | -0.006 | -0.1672 | No |
| 20 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 7189 | -0.018 | -0.2241 | No |
| 21 | EPS15 | EPS15 Entrez, Source | epidermal growth factor receptor pathway substrate 15 | 7677 | -0.026 | -0.2533 | No |
| 22 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 7751 | -0.027 | -0.2510 | No |
| 23 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 8170 | -0.033 | -0.2727 | No |
| 24 | ELF1 | ELF1 Entrez, Source | E74-like factor 1 (ets domain transcription factor) | 8198 | -0.034 | -0.2649 | No |
| 25 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 8522 | -0.039 | -0.2777 | No |
| 26 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 9289 | -0.052 | -0.3201 | No |
| 27 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 9528 | -0.056 | -0.3216 | No |
| 28 | XRCC6 | XRCC6 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) | 9780 | -0.062 | -0.3225 | No |
| 29 | PTPN11 | PTPN11 Entrez, Source | protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) | 11140 | -0.094 | -0.3972 | Yes |
| 30 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 11466 | -0.105 | -0.3912 | Yes |
| 31 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 11644 | -0.111 | -0.3722 | Yes |
| 32 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 11938 | -0.123 | -0.3584 | Yes |
| 33 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 12162 | -0.135 | -0.3359 | Yes |
| 34 | MAP3K10 | MAP3K10 Entrez, Source | mitogen-activated protein kinase kinase kinase 10 | 12375 | -0.147 | -0.3090 | Yes |
| 35 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 12387 | -0.148 | -0.2668 | Yes |
| 36 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 12557 | -0.159 | -0.2333 | Yes |
| 37 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 12876 | -0.196 | -0.2000 | Yes |
| 38 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 12936 | -0.206 | -0.1446 | Yes |
| 39 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 13175 | -0.284 | -0.0797 | Yes |
| 40 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 13220 | -0.317 | 0.0092 | Yes |
