Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IGF_VS_PDGF_DN |
| Enrichment Score (ES) | 0.7306228 |
| Normalized Enrichment Score (NES) | 2.047806 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0025155486 |
| FWER p-Value | 0.092 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MGP | MGP Entrez, Source | matrix Gla protein | 52 | 0.634 | 0.1944 | Yes |
| 2 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 142 | 0.455 | 0.3302 | Yes |
| 3 | THBD | THBD Entrez, Source | thrombomodulin | 474 | 0.236 | 0.3793 | Yes |
| 4 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 669 | 0.192 | 0.4247 | Yes |
| 5 | FBXO32 | FBXO32 Entrez, Source | F-box protein 32 | 694 | 0.186 | 0.4812 | Yes |
| 6 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 759 | 0.176 | 0.5314 | Yes |
| 7 | PRKG2 | PRKG2 Entrez, Source | protein kinase, cGMP-dependent, type II | 904 | 0.156 | 0.5695 | Yes |
| 8 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 943 | 0.152 | 0.6142 | Yes |
| 9 | CAV2 | CAV2 Entrez, Source | caveolin 2 | 1186 | 0.129 | 0.6365 | Yes |
| 10 | PHEX | PHEX Entrez, Source | phosphate regulating endopeptidase homolog, X-linked (hypophosphatemia, vitamin D resistant rickets) | 1351 | 0.116 | 0.6605 | Yes |
| 11 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 1504 | 0.108 | 0.6829 | Yes |
| 12 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 1684 | 0.098 | 0.7001 | Yes |
| 13 | ATP1A3 | ATP1A3 Entrez, Source | ATPase, Na+/K+ transporting, alpha 3 polypeptide | 1987 | 0.085 | 0.7042 | Yes |
| 14 | DUSP4 | DUSP4 Entrez, Source | dual specificity phosphatase 4 | 2400 | 0.071 | 0.6954 | Yes |
| 15 | ERRFI1 | ERRFI1 Entrez, Source | ERBB receptor feedback inhibitor 1 | 2488 | 0.068 | 0.7103 | Yes |
| 16 | CD53 | CD53 Entrez, Source | CD53 molecule | 2501 | 0.068 | 0.7306 | Yes |
| 17 | STOM | STOM Entrez, Source | stomatin | 3184 | 0.050 | 0.6951 | No |
| 18 | GREM1 | GREM1 Entrez, Source | gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis) | 3429 | 0.044 | 0.6907 | No |
| 19 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 3540 | 0.042 | 0.6955 | No |
| 20 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 5179 | 0.012 | 0.5763 | No |
| 21 | CRYL1 | CRYL1 Entrez, Source | crystallin, lambda 1 | 6010 | -0.000 | 0.5140 | No |
| 22 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 6341 | -0.005 | 0.4909 | No |
| 23 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 6731 | -0.011 | 0.4652 | No |
| 24 | DSCR1L1 | DSCR1L1 Entrez, Source | Down syndrome critical region gene 1-like 1 | 8243 | -0.035 | 0.3626 | No |
| 25 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 9912 | -0.065 | 0.2575 | No |
