Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetIGLESIAS_E2FMINUS_UP
Enrichment Score (ES)0.6650097
Normalized Enrichment Score (NES)2.404052
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: IGLESIAS_E2FMINUS_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 261.1540.0633Yes
2CCND2CCND2
Entrez,  Source
cyclin D2100.8850.1121Yes
3ANXA1ANXA1
Entrez,  Source
annexin A1110.8840.1610Yes
4SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4140.8300.2067Yes
5DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)180.7970.2506Yes
6COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)210.7850.2938Yes
7COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 2340.7140.3324Yes
8LPLLPL
Entrez,  Source
lipoprotein lipase450.6710.3688Yes
9COL4A1COL4A1
Entrez,  Source
collagen, type IV, alpha 1580.6250.4024Yes
10LGALS1LGALS1
Entrez,  Source
lectin, galactoside-binding, soluble, 1 (galectin 1)600.6140.4363Yes
11EMP1EMP1
Entrez,  Source
epithelial membrane protein 11010.5100.4615Yes
12GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)1730.4140.4790Yes
13SERPINH1SERPINH1
Entrez,  Source
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)1840.4030.5005Yes
14SERPINB6A2160.3720.5188Yes
15CFDCFD
Entrez,  Source
complement factor D (adipsin)2280.3650.5381Yes
16CD9CD9
Entrez,  Source
CD9 molecule2830.3200.5518Yes
17TMSB4XTMSB4X
Entrez,  Source
thymosin, beta 4, X-linked3150.2950.5657Yes
18SPARCSPARC
Entrez,  Source
secreted protein, acidic, cysteine-rich (osteonectin)3170.2930.5818Yes
19S100A6S100A6
Entrez,  Source
S100 calcium binding protein A63650.2740.5934Yes
20GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)4830.2330.5975Yes
21TYROBPTYROBP
Entrez,  Source
TYRO protein tyrosine kinase binding protein5860.2080.6013Yes
22COL6A2COL6A2
Entrez,  Source
collagen, type VI, alpha 26580.1950.6067Yes
23COL1A1COL1A1
Entrez,  Source
collagen, type I, alpha 16730.1900.6162Yes
24RHOBRHOB
Entrez,  Source
ras homolog gene family, member B7090.1840.6237Yes
25S100A11S100A11
Entrez,  Source
S100 calcium binding protein A117350.1790.6318Yes
26CTSECTSE
Entrez,  Source
cathepsin E7480.1770.6406Yes
27NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha7540.1760.6500Yes
28GAS6GAS6
Entrez,  Source
growth arrest-specific 68830.1580.6491Yes
29GNAI2GNAI2
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 29310.1530.6540Yes
30ACADLACADL
Entrez,  Source
acyl-Coenzyme A dehydrogenase, long chain9760.1490.6589Yes
31ANXA3ANXA3
Entrez,  Source
annexin A311700.1310.6516Yes
32GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta12100.1270.6556Yes
33CLK1CLK1
Entrez,  Source
CDC-like kinase 112620.1230.6586Yes
34IGSF4IGSF4
Entrez,  Source
immunoglobulin superfamily, member 413450.1170.6588Yes
35NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)13490.1160.6650Yes
36ARSAARSA
Entrez,  Source
arylsulfatase A15240.1070.6578No
37NFIBNFIB
Entrez,  Source
nuclear factor I/B15820.1030.6592No
38COL18A1COL18A1
Entrez,  Source
collagen, type XVIII, alpha 119420.0870.6369No
39ALAS2ALAS2
Entrez,  Source
aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia)20580.0830.6328No
40ACTA2ACTA2
Entrez,  Source
actin, alpha 2, smooth muscle, aorta20740.0820.6362No
41APOEAPOE
Entrez,  Source
apolipoprotein E21230.0800.6370No
42CD53CD53
Entrez,  Source
CD53 molecule25010.0680.6122No
43LCP1LCP1
Entrez,  Source
lymphocyte cytosolic protein 1 (L-plastin)28020.0600.5929No
44S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1029810.0550.5825No
45C1QBC1QB
Entrez,  Source
complement component 1, q subcomponent, B chain30170.0540.5828No
46CTSSCTSS
Entrez,  Source
cathepsin S30840.0520.5807No
47NPTNNPTN
Entrez,  Source
neuroplastin31530.0510.5784No
48SS18SS18
Entrez,  Source
synovial sarcoma translocation, chromosome 1832360.0490.5749No
49DCNDCN
Entrez,  Source
decorin34050.0450.5647No
50CD47CD47
Entrez,  Source
CD47 molecule37000.0390.5446No
51CAPZA2CAPZA2
Entrez,  Source
capping protein (actin filament) muscle Z-line, alpha 238400.0360.5361No
52ANXA2ANXA2
Entrez,  Source
annexin A239490.0340.5298No
53FBLN2FBLN2
Entrez,  Source
fibulin 240530.0320.5238No
54APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 241300.0300.5197No
55ELNELN
Entrez,  Source
elastin (supravalvular aortic stenosis, Williams-Beuren syndrome)43860.0260.5019No
56IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 545070.0230.4941No
57LUMLUM
Entrez,  Source
lumican45330.0230.4934No
58SKP1ASKP1A
Entrez,  Source
S-phase kinase-associated protein 1A (p19A)45830.0220.4910No
59SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 146970.0200.4835No
60CCNG1CCNG1
Entrez,  Source
cyclin G148770.0170.4710No
61ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain49410.0160.4671No
62C3C3
Entrez,  Source
complement component 353330.0100.4381No
63RBP1RBP1
Entrez,  Source
retinol binding protein 1, cellular54300.0080.4313No
64CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)55480.0070.4228No
65NID1NID1
Entrez,  Source
nidogen 155530.0070.4229No
66SCG2SCG2
Entrez,  Source
secretogranin II (chromogranin C)56140.0050.4186No
67CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)57040.0040.4121No
68SMAD1SMAD1
Entrez,  Source
SMAD, mothers against DPP homolog 1 (Drosophila)57310.0040.4104No
69B2MB2M
Entrez,  Source
beta-2-microglobulin57950.0030.4058No
70DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)58150.0030.4045No
71SEPT2SEPT2
Entrez,  Source
septin 258770.0020.4000No
72CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I6103-0.0020.3831No
73LMNALMNA
Entrez,  Source
lamin A/C6342-0.0050.3654No
74LYL1LYL1
Entrez,  Source
lymphoblastic leukemia derived sequence 16356-0.0060.3647No
75LAPTM5LAPTM5
Entrez,  Source
lysosomal associated multispanning membrane protein 56572-0.0090.3490No
76ANGPTL2ANGPTL2
Entrez,  Source
angiopoietin-like 26736-0.0110.3373No
77ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)6774-0.0120.3351No
78PMP22PMP22
Entrez,  Source
peripheral myelin protein 226796-0.0120.3342No
79EVLEVL
Entrez,  Source
Enah/Vasp-like6806-0.0120.3342No
80KITLGKITLG
Entrez,  Source
KIT ligand7033-0.0160.3180No
81CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)7147-0.0170.3104No
82COL15A1COL15A1
Entrez,  Source
collagen, type XV, alpha 17379-0.0210.2941No
83RBBP7RBBP7
Entrez,  Source
retinoblastoma binding protein 77634-0.0250.2763No
84ITM2BITM2B
Entrez,  Source
integral membrane protein 2B8067-0.0320.2454No
85CSRP1CSRP1
Entrez,  Source
cysteine and glycine-rich protein 18162-0.0330.2402No
86DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 18213-0.0340.2383No
87HBA-A18316-0.0360.2325No
88LAPTM4ALAPTM4A
Entrez,  Source
lysosomal-associated protein transmembrane 4 alpha8436-0.0380.2256No
89TIMM22TIMM22
Entrez,  Source
translocase of inner mitochondrial membrane 22 homolog (yeast)8545-0.0390.2197No
90IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 49082-0.0490.1819No
91ADIPOQADIPOQ
Entrez,  Source
adiponectin, C1Q and collagen domain containing9649-0.0590.1423No
92MORF4L1MORF4L1
Entrez,  Source
mortality factor 4 like 19926-0.0650.1251No
93RPS14RPS14
Entrez,  Source
ribosomal protein S1410600-0.0800.0786No
94BAXBAX
Entrez,  Source
BCL2-associated X protein10615-0.0800.0820No
95PCNAPCNA
Entrez,  Source
proliferating cell nuclear antigen11131-0.0940.0483No
96BZW1BZW1
Entrez,  Source
basic leucine zipper and W2 domains 111133-0.0940.0534No
97CTSZCTSZ
Entrez,  Source
cathepsin Z11497-0.1060.0319No
98CNN3CNN3
Entrez,  Source
calponin 3, acidic11628-0.1100.0282No
99GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 111712-0.1140.0282No
100ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)12368-0.147-0.0132No
101CACYBPCACYBP
Entrez,  Source
calcyclin binding protein12647-0.168-0.0249No
102ID2ID2
Entrez,  Source
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein12777-0.181-0.0246No
103TUBBTUBB
Entrez,  Source
tubulin, beta12909-0.201-0.0234No
104MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)13021-0.223-0.0195No
105UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase13081-0.242-0.0105No
106FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 113123-0.2590.0007No
107CES3CES3
Entrez,  Source
carboxylesterase 3 (brain)13178-0.2860.0124No
Table: GSEA details [plain text format]



Fig 2: IGLESIAS_E2FMINUS_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: IGLESIAS_E2FMINUS_UP: Random ES distribution   
Gene set null distribution of ES for IGLESIAS_E2FMINUS_UP