Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IL1_CORNEA_UP |
| Enrichment Score (ES) | 0.5800847 |
| Normalized Enrichment Score (NES) | 1.7719756 |
| Nominal p-value | 0.005376344 |
| FDR q-value | 0.03051619 |
| FWER p-Value | 0.987 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 50 | 0.641 | 0.1582 | Yes |
| 2 | PTPRZ1 | PTPRZ1 Entrez, Source | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 68 | 0.591 | 0.3065 | Yes |
| 3 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 138 | 0.458 | 0.4171 | Yes |
| 4 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 709 | 0.184 | 0.4208 | Yes |
| 5 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 789 | 0.172 | 0.4583 | Yes |
| 6 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1197 | 0.128 | 0.4600 | Yes |
| 7 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 1241 | 0.124 | 0.4882 | Yes |
| 8 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.5178 | Yes |
| 9 | MAFK | MAFK Entrez, Source | v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) | 1264 | 0.123 | 0.5486 | Yes |
| 10 | CDX2 | CDX2 Entrez, Source | caudal type homeobox transcription factor 2 | 1384 | 0.114 | 0.5686 | Yes |
| 11 | MERTK | MERTK Entrez, Source | c-mer proto-oncogene tyrosine kinase | 1808 | 0.092 | 0.5602 | Yes |
| 12 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 1849 | 0.091 | 0.5801 | Yes |
| 13 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2460 | 0.069 | 0.5517 | No |
| 14 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 2477 | 0.069 | 0.5678 | No |
| 15 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 2935 | 0.057 | 0.5478 | No |
| 16 | APOD | APOD Entrez, Source | apolipoprotein D | 3255 | 0.048 | 0.5360 | No |
| 17 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3285 | 0.048 | 0.5459 | No |
| 18 | KDR | KDR Entrez, Source | kinase insert domain receptor (a type III receptor tyrosine kinase) | 3567 | 0.041 | 0.5352 | No |
| 19 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 3732 | 0.038 | 0.5325 | No |
| 20 | PCP4 | PCP4 Entrez, Source | Purkinje cell protein 4 | 3747 | 0.038 | 0.5410 | No |
| 21 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3854 | 0.036 | 0.5420 | No |
| 22 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 3953 | 0.034 | 0.5432 | No |
| 23 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 4939 | 0.016 | 0.4732 | No |
| 24 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5174 | 0.012 | 0.4587 | No |
| 25 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 5599 | 0.006 | 0.4282 | No |
| 26 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 5682 | 0.005 | 0.4232 | No |
| 27 | KCNA1 | KCNA1 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 5912 | 0.001 | 0.4064 | No |
| 28 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 6101 | -0.002 | 0.3926 | No |
| 29 | GFRA2 | GFRA2 Entrez, Source | GDNF family receptor alpha 2 | 7521 | -0.023 | 0.2918 | No |
| 30 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 7731 | -0.026 | 0.2827 | No |
| 31 | FSTL3 | FSTL3 Entrez, Source | follistatin-like 3 (secreted glycoprotein) | 7760 | -0.027 | 0.2873 | No |
| 32 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 7899 | -0.029 | 0.2843 | No |
| 33 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 8913 | -0.046 | 0.2198 | No |
| 34 | TNP2 | TNP2 Entrez, Source | transition protein 2 (during histone to protamine replacement) | 9218 | -0.051 | 0.2098 | No |
| 35 | SECTM1 | SECTM1 Entrez, Source | secreted and transmembrane 1 | 9756 | -0.061 | 0.1849 | No |
| 36 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | 0.1455 | No |
| 37 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 11710 | -0.114 | 0.0868 | No |
| 38 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 12287 | -0.141 | 0.0793 | No |
