Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | IRITANI_ADPROX_DN |
| Enrichment Score (ES) | 0.60251087 |
| Normalized Enrichment Score (NES) | 1.854346 |
| Nominal p-value | 0.0018656716 |
| FDR q-value | 0.018056316 |
| FWER p-Value | 0.828 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 22 | 0.785 | 0.1279 | Yes |
| 2 | PROCR | PROCR Entrez, Source | protein C receptor, endothelial (EPCR) | 37 | 0.690 | 0.2408 | Yes |
| 3 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 56 | 0.628 | 0.3430 | Yes |
| 4 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 141 | 0.455 | 0.4119 | Yes |
| 5 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 145 | 0.452 | 0.4862 | Yes |
| 6 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 454 | 0.244 | 0.5033 | Yes |
| 7 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 533 | 0.219 | 0.5337 | Yes |
| 8 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 721 | 0.182 | 0.5497 | Yes |
| 9 | EMP3 | EMP3 Entrez, Source | epithelial membrane protein 3 | 755 | 0.176 | 0.5763 | Yes |
| 10 | LPXN | LPXN Entrez, Source | leupaxin | 785 | 0.172 | 0.6025 | Yes |
| 11 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 1373 | 0.115 | 0.5774 | No |
| 12 | ANXA6 | ANXA6 Entrez, Source | annexin A6 | 1439 | 0.111 | 0.5909 | No |
| 13 | SLC38A6 | SLC38A6 Entrez, Source | solute carrier family 38, member 6 | 1678 | 0.098 | 0.5892 | No |
| 14 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 1774 | 0.094 | 0.5976 | No |
| 15 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 1991 | 0.085 | 0.5954 | No |
| 16 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 2789 | 0.060 | 0.5455 | No |
| 17 | ARL6IP5 | ARL6IP5 Entrez, Source | ADP-ribosylation-like factor 6 interacting protein 5 | 2947 | 0.056 | 0.5429 | No |
| 18 | LTBP2 | LTBP2 Entrez, Source | latent transforming growth factor beta binding protein 2 | 3107 | 0.052 | 0.5395 | No |
| 19 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3854 | 0.036 | 0.4893 | No |
| 20 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 4498 | 0.023 | 0.4448 | No |
| 21 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4688 | 0.020 | 0.4339 | No |
| 22 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 4730 | 0.020 | 0.4341 | No |
| 23 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 4808 | 0.018 | 0.4313 | No |
| 24 | MAPKAPK3 | MAPKAPK3 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 3 | 5339 | 0.009 | 0.3930 | No |
| 25 | ICAM2 | ICAM2 Entrez, Source | intercellular adhesion molecule 2 | 5448 | 0.008 | 0.3862 | No |
| 26 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 5738 | 0.004 | 0.3651 | No |
| 27 | LYL1 | LYL1 Entrez, Source | lymphoblastic leukemia derived sequence 1 | 6356 | -0.006 | 0.3196 | No |
| 28 | TFEC | TFEC Entrez, Source | transcription factor EC | 6760 | -0.012 | 0.2913 | No |
| 29 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 7114 | -0.017 | 0.2675 | No |
| 30 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 7290 | -0.019 | 0.2576 | No |
| 31 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 8086 | -0.032 | 0.2031 | No |
| 32 | MLLT11 | MLLT11 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 9154 | -0.050 | 0.1311 | No |
| 33 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 9690 | -0.060 | 0.1007 | No |
| 34 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 10004 | -0.066 | 0.0882 | No |
| 35 | CAP2 | CAP2 Entrez, Source | CAP, adenylate cyclase-associated protein, 2 (yeast) | 10317 | -0.073 | 0.0768 | No |
| 36 | SRPX | SRPX Entrez, Source | sushi-repeat-containing protein, X-linked | 10360 | -0.074 | 0.0858 | No |
| 37 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 11212 | -0.096 | 0.0377 | No |
| 38 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 11891 | -0.121 | 0.0067 | No |
| 39 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12802 | -0.185 | -0.0311 | No |
| 40 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 12940 | -0.207 | -0.0073 | No |
| 41 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 13035 | -0.227 | 0.0231 | No |
