Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetIRITANI_ADPROX_VASC
Enrichment Score (ES)0.6016314
Normalized Enrichment Score (NES)2.1842916
Nominal p-value0.0
FDR q-value4.3921336E-4
FWER p-Value0.0050
Table: GSEA Results Summary



Fig 1: Enrichment plot: IRITANI_ADPROX_VASC   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 261.1540.0808Yes
2LAMC2LAMC2
Entrez,  Source
laminin, gamma 2190.7910.1357Yes
3LDHBLDHB
Entrez,  Source
lactate dehydrogenase B220.7850.1909Yes
4CLDN7CLDN7
Entrez,  Source
claudin 7240.7800.2457Yes
5PROCRPROCR
Entrez,  Source
protein C receptor, endothelial (EPCR)370.6900.2935Yes
6SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1560.6280.3364Yes
7PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)1410.4550.3621Yes
8CCL2CCL2
Entrez,  Source
chemokine (C-C motif) ligand 21450.4520.3937Yes
9BGNBGN
Entrez,  Source
biglycan1750.4080.4203Yes
10TAGLNTAGLN
Entrez,  Source
transgelin2500.3440.4389Yes
11RGS10RGS10
Entrez,  Source
regulator of G-protein signalling 103700.2720.4492Yes
12IER3IER3
Entrez,  Source
immediate early response 33920.2640.4662Yes
13RGS4RGS4
Entrez,  Source
regulator of G-protein signalling 44540.2440.4787Yes
14CD59CD59
Entrez,  Source
CD59 molecule, complement regulatory protein5330.2190.4883Yes
15RHOBRHOB
Entrez,  Source
ras homolog gene family, member B7090.1840.4881Yes
16IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 37210.1820.5001Yes
17VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C7780.1730.5080Yes
18LPXNLPXN
Entrez,  Source
leupaxin7850.1720.5197Yes
19FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)7890.1720.5316Yes
20BTG2BTG2
Entrez,  Source
BTG family, member 28800.1590.5360Yes
21ECE1ECE1
Entrez,  Source
endothelin converting enzyme 19250.1530.5435Yes
22EIF2B2EIF2B2
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa9750.1490.5503Yes
23CXCL1CXCL1
Entrez,  Source
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)10410.1420.5554Yes
24BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 111050.1360.5602Yes
25ANXA3ANXA3
Entrez,  Source
annexin A311700.1310.5646Yes
26MT1AMT1A
Entrez,  Source
metallothionein 1A (functional)12500.1240.5673Yes
27PKIAPKIA
Entrez,  Source
protein kinase (cAMP-dependent, catalytic) inhibitor alpha13400.1170.5689Yes
28AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase13730.1150.5745Yes
29ANXA6ANXA6
Entrez,  Source
annexin A614390.1110.5775Yes
30LAMA5LAMA5
Entrez,  Source
laminin, alpha 514660.1100.5833Yes
31TGM2TGM2
Entrez,  Source
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)16500.1000.5765Yes
32SLC38A6SLC38A6
Entrez,  Source
solute carrier family 38, member 616780.0980.5814Yes
33UPP1UPP1
Entrez,  Source
uridine phosphorylase 116790.0980.5883Yes
34CAPGCAPG
Entrez,  Source
capping protein (actin filament), gelsolin-like16840.0980.5949Yes
35LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 217440.0950.5972Yes
36ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta17740.0940.6016Yes
37TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia19910.0850.5913No
38ACTA2ACTA2
Entrez,  Source
actin, alpha 2, smooth muscle, aorta20740.0820.5909No
39ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide23950.0710.5717No
40NISCHNISCH
Entrez,  Source
nischarin25680.0660.5634No
41SELPSELP
Entrez,  Source
selectin P (granule membrane protein 140kDa, antigen CD62)27890.0600.5510No
42ARL6IP5ARL6IP5
Entrez,  Source
ADP-ribosylation-like factor 6 interacting protein 529470.0560.5431No
43JUNJUN
Entrez,  Source
jun oncogene31040.0520.5350No
44LTBP2LTBP2
Entrez,  Source
latent transforming growth factor beta binding protein 231070.0520.5385No
45ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)32450.0480.5315No
46CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)35060.0430.5149No
47CLUCLU
Entrez,  Source
clusterin37390.0380.5001No
48IL6IL6
Entrez,  Source
interleukin 6 (interferon, beta 2)38540.0360.4940No
49SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 138800.0350.4945No
50LPHN2LPHN2
Entrez,  Source
latrophilin 244300.0250.4548No
51IL4RIL4R
Entrez,  Source
interleukin 4 receptor44940.0240.4517No
52BMP6BMP6
Entrez,  Source
bone morphogenetic protein 644980.0230.4532No
53PLA2G4APLA2G4A
Entrez,  Source
phospholipase A2, group IVA (cytosolic, calcium-dependent)46880.0200.4403No
54SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)47200.0200.4394No
55MMP14MMP14
Entrez,  Source
matrix metallopeptidase 14 (membrane-inserted)48080.0180.4341No
56PGFPGF
Entrez,  Source
placental growth factor, vascular endothelial growth factor-related protein51430.0120.4097No
57CHST1CHST1
Entrez,  Source
carbohydrate (keratan sulfate Gal-6) sulfotransferase 152610.0110.4017No
58MAPKAPK3MAPKAPK3
Entrez,  Source
mitogen-activated protein kinase-activated protein kinase 353390.0090.3965No
59TGFBITGFBI
Entrez,  Source
transforming growth factor, beta-induced, 68kDa54390.0080.3896No
60ICAM2ICAM2
Entrez,  Source
intercellular adhesion molecule 254480.0080.3896No
61PFN2PFN2
Entrez,  Source
profilin 254910.0070.3869No
62NR2F2NR2F2
Entrez,  Source
nuclear receptor subfamily 2, group F, member 255650.0060.3819No
63PFKMPFKM
Entrez,  Source
phosphofructokinase, muscle57380.0040.3691No
64CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 459810.0000.3509No
65MT3MT3
Entrez,  Source
metallothionein 3 (growth inhibitory factor (neurotrophic))6193-0.0030.3352No
66LYL1LYL1
Entrez,  Source
lymphoblastic leukemia derived sequence 16356-0.0060.3233No
67ENO2ENO2
Entrez,  Source
enolase 2 (gamma, neuronal)6473-0.0070.3151No
68AGRINAGRIN
Entrez,  Source
agrin6677-0.0100.3005No
69TFECTFEC
Entrez,  Source
transcription factor EC6760-0.0120.2951No
70ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)6961-0.0140.2810No
71TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)7114-0.0170.2707No
72CDH2CDH2
Entrez,  Source
cadherin 2, type 1, N-cadherin (neuronal)7290-0.0190.2589No
73RAC2RAC2
Entrez,  Source
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)7555-0.0230.2406No
74TXNRD2TXNRD2
Entrez,  Source
thioredoxin reductase 27578-0.0240.2406No
75PDLIM4PDLIM4
Entrez,  Source
PDZ and LIM domain 48086-0.0320.2046No
76EFEMP1EFEMP1
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 18124-0.0330.2041No
77MLLT11MLLT11
Entrez,  Source
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 119154-0.0500.1299No
78FHL2FHL2
Entrez,  Source
four and a half LIM domains 29173-0.0500.1321No
79MVPMVP
Entrez,  Source
major vault protein9188-0.0500.1346No
80CTSCCTSC
Entrez,  Source
cathepsin C9429-0.0550.1203No
81CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)9690-0.0600.1049No
82ITGB5ITGB5
Entrez,  Source
integrin, beta 59946-0.0650.0902No
83PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule10004-0.0660.0906No
84GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha10152-0.0690.0844No
85CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)10317-0.0730.0771No
86SRPXSRPX
Entrez,  Source
sushi-repeat-containing protein, X-linked10360-0.0740.0792No
87SELESELE
Entrez,  Source
selectin E (endothelial adhesion molecule 1)10446-0.0760.0781No
88ICAM1ICAM1
Entrez,  Source
intercellular adhesion molecule 1 (CD54), human rhinovirus receptor10770-0.0850.0597No
89UCHL1UCHL1
Entrez,  Source
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)11042-0.0920.0457No
90SORDSORD
Entrez,  Source
sorbitol dehydrogenase11046-0.0920.0519No
91TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 211118-0.0940.0532No
92SLC6A8SLC6A8
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, creatine), member 811161-0.0950.0567No
93FAPFAP
Entrez,  Source
fibroblast activation protein, alpha11212-0.0960.0596No
94NMT2NMT2
Entrez,  Source
N-myristoyltransferase 211273-0.0980.0620No
95PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase11891-0.1210.0240No
96CD44CD44
Entrez,  Source
CD44 molecule (Indian blood group)12802-0.185-0.0317No
97GBP2GBP2
Entrez,  Source
guanylate binding protein 2, interferon-inducible12940-0.207-0.0275No
98NRCAMNRCAM
Entrez,  Source
neuronal cell adhesion molecule13035-0.227-0.0186No
99SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 713061-0.237-0.0037No
100SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 213255-0.3530.0066No
Table: GSEA details [plain text format]



Fig 2: IRITANI_ADPROX_VASC   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: IRITANI_ADPROX_VASC: Random ES distribution   
Gene set null distribution of ES for IRITANI_ADPROX_VASC