Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | JAIN_NEMO_DIFF |
| Enrichment Score (ES) | -0.5357835 |
| Normalized Enrichment Score (NES) | -1.7296373 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.073833674 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DECR1 | DECR1 Entrez, Source | 2,4-dienoyl CoA reductase 1, mitochondrial | 378 | 0.269 | 0.0283 | No |
| 2 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 789 | 0.172 | 0.0336 | No |
| 3 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 1483 | 0.109 | 0.0046 | No |
| 4 | DCTN1 | DCTN1 Entrez, Source | dynactin 1 (p150, glued homolog, Drosophila) | 1537 | 0.106 | 0.0228 | No |
| 5 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 2056 | 0.083 | 0.0014 | No |
| 6 | PEX14 | PEX14 Entrez, Source | peroxisomal biogenesis factor 14 | 2271 | 0.075 | 0.0011 | No |
| 7 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 2391 | 0.071 | 0.0071 | No |
| 8 | HK2 | HK2 Entrez, Source | hexokinase 2 | 2661 | 0.063 | 0.0002 | No |
| 9 | ARSB | ARSB Entrez, Source | arylsulfatase B | 3312 | 0.047 | -0.0387 | No |
| 10 | SLC23A2 | SLC23A2 Entrez, Source | solute carrier family 23 (nucleobase transporters), member 2 | 4740 | 0.019 | -0.1418 | No |
| 11 | TM7SF2 | TM7SF2 Entrez, Source | transmembrane 7 superfamily member 2 | 6881 | -0.013 | -0.2999 | No |
| 12 | SPHK2 | SPHK2 Entrez, Source | sphingosine kinase 2 | 6993 | -0.015 | -0.3050 | No |
| 13 | BCAT2 | BCAT2 Entrez, Source | branched chain aminotransferase 2, mitochondrial | 7503 | -0.022 | -0.3386 | No |
| 14 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8469 | -0.038 | -0.4030 | No |
| 15 | PSMA2 | PSMA2 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 2 | 8901 | -0.046 | -0.4257 | No |
| 16 | CTSC | CTSC Entrez, Source | cathepsin C | 9429 | -0.055 | -0.4538 | No |
| 17 | TPD52L2 | TPD52L2 Entrez, Source | tumor protein D52-like 2 | 9634 | -0.058 | -0.4568 | No |
| 18 | SYMPK | SYMPK Entrez, Source | symplekin | 10270 | -0.072 | -0.4894 | No |
| 19 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 10281 | -0.072 | -0.4750 | No |
| 20 | LIG3 | LIG3 Entrez, Source | ligase III, DNA, ATP-dependent | 10864 | -0.087 | -0.5004 | No |
| 21 | PRR3 | PRR3 Entrez, Source | proline rich 3 | 11198 | -0.096 | -0.5052 | No |
| 22 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 11386 | -0.102 | -0.4979 | No |
| 23 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 11891 | -0.121 | -0.5103 | Yes |
| 24 | XPO7 | XPO7 Entrez, Source | exportin 7 | 12002 | -0.127 | -0.4918 | Yes |
| 25 | PTPN7 | PTPN7 Entrez, Source | protein tyrosine phosphatase, non-receptor type 7 | 12273 | -0.141 | -0.4825 | Yes |
| 26 | DDX46 | DDX46 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 12587 | -0.162 | -0.4719 | Yes |
| 27 | ALG3 | ALG3 Entrez, Source | asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase) | 12651 | -0.168 | -0.4412 | Yes |
| 28 | TRMT1 | TRMT1 Entrez, Source | TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae) | 12658 | -0.169 | -0.4061 | Yes |
| 29 | PMVK | PMVK Entrez, Source | phosphomevalonate kinase | 12750 | -0.178 | -0.3755 | Yes |
| 30 | FBL | FBL Entrez, Source | fibrillarin | 12880 | -0.197 | -0.3436 | Yes |
| 31 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 12934 | -0.205 | -0.3044 | Yes |
| 32 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 12972 | -0.213 | -0.2623 | Yes |
| 33 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 13062 | -0.238 | -0.2189 | Yes |
| 34 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13244 | -0.339 | -0.1612 | Yes |
| 35 | TAP2 | TAP2 Entrez, Source | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 13278 | -0.393 | -0.0809 | Yes |
| 36 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13286 | -0.407 | 0.0042 | Yes |
