Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | LEE_ACOX1_DN |
| Enrichment Score (ES) | -0.37937638 |
| Normalized Enrichment Score (NES) | -1.2582648 |
| Nominal p-value | 0.14153132 |
| FDR q-value | 0.5272677 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 57 | 0.628 | 0.0710 | No |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 144 | 0.453 | 0.1189 | No |
| 3 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 146 | 0.449 | 0.1727 | No |
| 4 | LIPC | LIPC Entrez, Source | lipase, hepatic | 193 | 0.397 | 0.2168 | No |
| 5 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 514 | 0.223 | 0.2196 | No |
| 6 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 538 | 0.219 | 0.2441 | No |
| 7 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 573 | 0.211 | 0.2670 | No |
| 8 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 616 | 0.203 | 0.2882 | No |
| 9 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 906 | 0.156 | 0.2852 | No |
| 10 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 1038 | 0.143 | 0.2924 | No |
| 11 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 1065 | 0.139 | 0.3072 | No |
| 12 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 1221 | 0.126 | 0.3107 | No |
| 13 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 1525 | 0.107 | 0.3007 | No |
| 14 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 1720 | 0.096 | 0.2977 | No |
| 15 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 1931 | 0.087 | 0.2924 | No |
| 16 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 2436 | 0.070 | 0.2628 | No |
| 17 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4885 | 0.017 | 0.0808 | No |
| 18 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 5350 | 0.009 | 0.0470 | No |
| 19 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 5402 | 0.009 | 0.0442 | No |
| 20 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 5862 | 0.002 | 0.0100 | No |
| 21 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 5925 | 0.001 | 0.0054 | No |
| 22 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 6493 | -0.008 | -0.0363 | No |
| 23 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 7953 | -0.030 | -0.1424 | No |
| 24 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 8984 | -0.047 | -0.2142 | No |
| 25 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 9179 | -0.050 | -0.2228 | No |
| 26 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 9273 | -0.052 | -0.2235 | No |
| 27 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 9459 | -0.055 | -0.2308 | No |
| 28 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 9637 | -0.058 | -0.2371 | No |
| 29 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 9699 | -0.060 | -0.2345 | No |
| 30 | GSTA3 | GSTA3 Entrez, Source | glutathione S-transferase A3 | 10304 | -0.073 | -0.2712 | No |
| 31 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 10399 | -0.075 | -0.2693 | No |
| 32 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 10574 | -0.079 | -0.2729 | No |
| 33 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 10785 | -0.085 | -0.2785 | No |
| 34 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 11455 | -0.104 | -0.3163 | No |
| 35 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 12080 | -0.131 | -0.3475 | No |
| 36 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 12485 | -0.154 | -0.3594 | Yes |
| 37 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 12751 | -0.178 | -0.3580 | Yes |
| 38 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 12757 | -0.178 | -0.3370 | Yes |
| 39 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12857 | -0.193 | -0.3213 | Yes |
| 40 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 12934 | -0.205 | -0.3024 | Yes |
| 41 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 13087 | -0.247 | -0.2843 | Yes |
| 42 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 13116 | -0.257 | -0.2555 | Yes |
| 43 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 13297 | -0.441 | -0.2161 | Yes |
| 44 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 13309 | -0.475 | -0.1599 | Yes |
| 45 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13327 | -0.634 | -0.0851 | Yes |
| 46 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13331 | -0.718 | 0.0008 | Yes |
