Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_DENA_UP |
| Enrichment Score (ES) | 0.7210738 |
| Normalized Enrichment Score (NES) | 2.2336192 |
| Nominal p-value | 0.0 |
| FDR q-value | 2.9460265E-4 |
| FWER p-Value | 0.0020 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 11 | 0.884 | 0.1025 | Yes |
| 2 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 25 | 0.771 | 0.1917 | Yes |
| 3 | CD24 | CD24 Entrez, Source | CD24 molecule | 26 | 0.771 | 0.2818 | Yes |
| 4 | LPL | LPL Entrez, Source | lipoprotein lipase | 45 | 0.671 | 0.3588 | Yes |
| 5 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 58 | 0.625 | 0.4310 | Yes |
| 6 | ANKRD1 | ANKRD1 Entrez, Source | ankyrin repeat domain 1 (cardiac muscle) | 93 | 0.529 | 0.4903 | Yes |
| 7 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 177 | 0.408 | 0.5318 | Yes |
| 8 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 230 | 0.365 | 0.5705 | Yes |
| 9 | PEA15 | PEA15 Entrez, Source | phosphoprotein enriched in astrocytes 15 | 279 | 0.322 | 0.6045 | Yes |
| 10 | TM4SF4 | TM4SF4 Entrez, Source | transmembrane 4 L six family member 4 | 339 | 0.286 | 0.6336 | Yes |
| 11 | LEPR | LEPR Entrez, Source | leptin receptor | 471 | 0.237 | 0.6514 | Yes |
| 12 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 516 | 0.223 | 0.6742 | Yes |
| 13 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 584 | 0.209 | 0.6936 | Yes |
| 14 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 843 | 0.163 | 0.6933 | Yes |
| 15 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 884 | 0.158 | 0.7087 | Yes |
| 16 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1191 | 0.129 | 0.7008 | Yes |
| 17 | B4GALT6 | B4GALT6 Entrez, Source | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | 1451 | 0.111 | 0.6942 | Yes |
| 18 | LAMA5 | LAMA5 Entrez, Source | laminin, alpha 5 | 1466 | 0.110 | 0.7060 | Yes |
| 19 | GPC3 | GPC3 Entrez, Source | glypican 3 | 1656 | 0.100 | 0.7035 | Yes |
| 20 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 1672 | 0.099 | 0.7139 | Yes |
| 21 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.7171 | Yes |
| 22 | LGMN | LGMN Entrez, Source | legumain | 1864 | 0.090 | 0.7211 | Yes |
| 23 | CTSS | CTSS Entrez, Source | cathepsin S | 3084 | 0.052 | 0.6355 | No |
| 24 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3285 | 0.048 | 0.6261 | No |
| 25 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 3949 | 0.034 | 0.5802 | No |
| 26 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 4053 | 0.032 | 0.5762 | No |
| 27 | CPE | CPE Entrez, Source | carboxypeptidase E | 4444 | 0.025 | 0.5497 | No |
| 28 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 4689 | 0.020 | 0.5337 | No |
| 29 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 5175 | 0.012 | 0.4987 | No |
| 30 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 5480 | 0.008 | 0.4767 | No |
| 31 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 6196 | -0.003 | 0.4233 | No |
| 32 | PPBP | PPBP Entrez, Source | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 7274 | -0.019 | 0.3446 | No |
| 33 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 7557 | -0.023 | 0.3261 | No |
| 34 | PLEK | PLEK Entrez, Source | pleckstrin | 7997 | -0.031 | 0.2967 | No |
| 35 | APCS | APCS Entrez, Source | amyloid P component, serum | 9703 | -0.060 | 0.1755 | No |
| 36 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 9785 | -0.062 | 0.1767 | No |
| 37 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 9836 | -0.063 | 0.1803 | No |
| 38 | CD63 | CD63 Entrez, Source | CD63 molecule | 10073 | -0.068 | 0.1705 | No |
| 39 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 11137 | -0.094 | 0.1016 | No |
| 40 | CSN3 | CSN3 Entrez, Source | casein kappa | 11177 | -0.095 | 0.1097 | No |
| 41 | SOX9 | SOX9 Entrez, Source | SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) | 12407 | -0.149 | 0.0347 | No |
| 42 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13204 | -0.304 | 0.0104 | No |
