Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_E2F1_UP |
| Enrichment Score (ES) | 0.6281414 |
| Normalized Enrichment Score (NES) | 1.9750988 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0056768954 |
| FWER p-Value | 0.274 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 11 | 0.884 | 0.0892 | Yes |
| 2 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 34 | 0.714 | 0.1601 | Yes |
| 3 | LPL | LPL Entrez, Source | lipoprotein lipase | 45 | 0.671 | 0.2277 | Yes |
| 4 | GSTM2 | GSTM2 Entrez, Source | glutathione S-transferase M2 (muscle) | 114 | 0.485 | 0.2720 | Yes |
| 5 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 177 | 0.408 | 0.3088 | Yes |
| 6 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 230 | 0.365 | 0.3420 | Yes |
| 7 | DEFB1 | DEFB1 Entrez, Source | defensin, beta 1 | 234 | 0.360 | 0.3784 | Yes |
| 8 | FMO3 | FMO3 Entrez, Source | flavin containing monooxygenase 3 | 281 | 0.322 | 0.4077 | Yes |
| 9 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 317 | 0.293 | 0.4350 | Yes |
| 10 | TM4SF4 | TM4SF4 Entrez, Source | transmembrane 4 L six family member 4 | 339 | 0.286 | 0.4625 | Yes |
| 11 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 376 | 0.270 | 0.4873 | Yes |
| 12 | LEPR | LEPR Entrez, Source | leptin receptor | 471 | 0.237 | 0.5043 | Yes |
| 13 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 584 | 0.209 | 0.5172 | Yes |
| 14 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 673 | 0.190 | 0.5300 | Yes |
| 15 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 709 | 0.184 | 0.5460 | Yes |
| 16 | ACTG2 | ACTG2 Entrez, Source | actin, gamma 2, smooth muscle, enteric | 711 | 0.183 | 0.5646 | Yes |
| 17 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 743 | 0.177 | 0.5804 | Yes |
| 18 | CTSE | CTSE Entrez, Source | cathepsin E | 748 | 0.177 | 0.5981 | Yes |
| 19 | MFGE8 | MFGE8 Entrez, Source | milk fat globule-EGF factor 8 protein | 843 | 0.163 | 0.6076 | Yes |
| 20 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 884 | 0.158 | 0.6207 | Yes |
| 21 | PALMD | PALMD Entrez, Source | palmdelphin | 986 | 0.148 | 0.6281 | Yes |
| 22 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 1191 | 0.129 | 0.6259 | No |
| 23 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 1557 | 0.105 | 0.6091 | No |
| 24 | GPC3 | GPC3 Entrez, Source | glypican 3 | 1656 | 0.100 | 0.6119 | No |
| 25 | CXADR | CXADR Entrez, Source | coxsackie virus and adenovirus receptor | 1853 | 0.090 | 0.6064 | No |
| 26 | CTSS | CTSS Entrez, Source | cathepsin S | 3084 | 0.052 | 0.5192 | No |
| 27 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 3285 | 0.048 | 0.5090 | No |
| 28 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 3949 | 0.034 | 0.4626 | No |
| 29 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 4349 | 0.026 | 0.4352 | No |
| 30 | CPE | CPE Entrez, Source | carboxypeptidase E | 4444 | 0.025 | 0.4307 | No |
| 31 | CSTB | CSTB Entrez, Source | cystatin B (stefin B) | 4447 | 0.024 | 0.4330 | No |
| 32 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 4848 | 0.018 | 0.4047 | No |
| 33 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 5017 | 0.015 | 0.3936 | No |
| 34 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 5175 | 0.012 | 0.3830 | No |
| 35 | TFF3 | TFF3 Entrez, Source | trefoil factor 3 (intestinal) | 5480 | 0.008 | 0.3609 | No |
| 36 | TAGLN2 | TAGLN2 Entrez, Source | transgelin 2 | 6196 | -0.003 | 0.3075 | No |
| 37 | NT5E | NT5E Entrez, Source | 5'-nucleotidase, ecto (CD73) | 7715 | -0.026 | 0.1960 | No |
| 38 | SPON2 | SPON2 Entrez, Source | spondin 2, extracellular matrix protein | 8759 | -0.043 | 0.1219 | No |
| 39 | XDH | XDH Entrez, Source | xanthine dehydrogenase | 9455 | -0.055 | 0.0753 | No |
| 40 | CD63 | CD63 Entrez, Source | CD63 molecule | 10073 | -0.068 | 0.0358 | No |
| 41 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12405 | -0.149 | -0.1244 | No |
| 42 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 12871 | -0.195 | -0.1395 | No |
| 43 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12902 | -0.200 | -0.1214 | No |
| 44 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 13300 | -0.447 | -0.1057 | No |
| 45 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13301 | -0.450 | -0.0598 | No |
| 46 | CD74 | CD74 Entrez, Source | CD74 molecule, major histocompatibility complex, class II invariant chain | 13325 | -0.617 | 0.0013 | No |
