Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_MYC_DN |
| Enrichment Score (ES) | 0.622604 |
| Normalized Enrichment Score (NES) | 1.9149414 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010867761 |
| FWER p-Value | 0.54 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 35 | 0.711 | 0.0937 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 57 | 0.628 | 0.1772 | Yes |
| 3 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 103 | 0.505 | 0.2422 | Yes |
| 4 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 123 | 0.473 | 0.3049 | Yes |
| 5 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 133 | 0.466 | 0.3674 | Yes |
| 6 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 144 | 0.453 | 0.4280 | Yes |
| 7 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 448 | 0.245 | 0.4384 | Yes |
| 8 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 466 | 0.240 | 0.4697 | Yes |
| 9 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 514 | 0.223 | 0.4964 | Yes |
| 10 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 666 | 0.194 | 0.5114 | Yes |
| 11 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 669 | 0.192 | 0.5372 | Yes |
| 12 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 682 | 0.188 | 0.5618 | Yes |
| 13 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 934 | 0.153 | 0.5637 | Yes |
| 14 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 1038 | 0.143 | 0.5752 | Yes |
| 15 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 1065 | 0.139 | 0.5922 | Yes |
| 16 | PCOLCE | PCOLCE Entrez, Source | procollagen C-endopeptidase enhancer | 1214 | 0.126 | 0.5981 | Yes |
| 17 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 1230 | 0.125 | 0.6140 | Yes |
| 18 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 1483 | 0.109 | 0.6098 | Yes |
| 19 | DMBT1 | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 1508 | 0.108 | 0.6226 | Yes |
| 20 | SFXN1 | SFXN1 Entrez, Source | sideroflexin 1 | 1842 | 0.091 | 0.6099 | No |
| 21 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 1859 | 0.090 | 0.6209 | No |
| 22 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 2276 | 0.075 | 0.5997 | No |
| 23 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 3402 | 0.045 | 0.5212 | No |
| 24 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 3540 | 0.042 | 0.5166 | No |
| 25 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4037 | 0.032 | 0.4837 | No |
| 26 | ZG16 | ZG16 Entrez, Source | - | 5250 | 0.011 | 0.3940 | No |
| 27 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 5402 | 0.009 | 0.3838 | No |
| 28 | CFH | CFH Entrez, Source | complement factor H | 7191 | -0.018 | 0.2519 | No |
| 29 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 7828 | -0.028 | 0.2078 | No |
| 30 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 7950 | -0.030 | 0.2028 | No |
| 31 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 8124 | -0.033 | 0.1942 | No |
| 32 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 9637 | -0.058 | 0.0884 | No |
| 33 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 9982 | -0.066 | 0.0715 | No |
| 34 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 10416 | -0.075 | 0.0491 | No |
| 35 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 10785 | -0.085 | 0.0329 | No |
| 36 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 10955 | -0.089 | 0.0323 | No |
| 37 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 10956 | -0.089 | 0.0444 | No |
| 38 | HSPH1 | HSPH1 Entrez, Source | heat shock 105kDa/110kDa protein 1 | 11297 | -0.099 | 0.0322 | No |
| 39 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 11422 | -0.103 | 0.0368 | No |
| 40 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 12080 | -0.131 | 0.0051 | No |
| 41 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12857 | -0.193 | -0.0271 | No |
| 42 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 12923 | -0.203 | -0.0045 | No |
| 43 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13137 | -0.265 | 0.0154 | No |
