Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_MYC_E2F1_DN |
| Enrichment Score (ES) | 0.5836159 |
| Normalized Enrichment Score (NES) | 1.8155458 |
| Nominal p-value | 0.0036429872 |
| FDR q-value | 0.02266133 |
| FWER p-Value | 0.937 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 35 | 0.711 | 0.0850 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 57 | 0.628 | 0.1607 | Yes |
| 3 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 103 | 0.505 | 0.2196 | Yes |
| 4 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 121 | 0.476 | 0.2769 | Yes |
| 5 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 144 | 0.453 | 0.3311 | Yes |
| 6 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 389 | 0.265 | 0.3453 | Yes |
| 7 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 408 | 0.257 | 0.3755 | Yes |
| 8 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 456 | 0.243 | 0.4019 | Yes |
| 9 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 514 | 0.223 | 0.4252 | Yes |
| 10 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 580 | 0.210 | 0.4462 | Yes |
| 11 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 605 | 0.206 | 0.4697 | Yes |
| 12 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 616 | 0.203 | 0.4940 | Yes |
| 13 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 669 | 0.192 | 0.5137 | Yes |
| 14 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 734 | 0.180 | 0.5310 | Yes |
| 15 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 906 | 0.156 | 0.5373 | Yes |
| 16 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 934 | 0.153 | 0.5541 | Yes |
| 17 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 964 | 0.151 | 0.5705 | Yes |
| 18 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 1038 | 0.143 | 0.5826 | Yes |
| 19 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 1230 | 0.125 | 0.5836 | Yes |
| 20 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 1720 | 0.096 | 0.5587 | No |
| 21 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 1859 | 0.090 | 0.5595 | No |
| 22 | GHR | GHR Entrez, Source | growth hormone receptor | 2098 | 0.081 | 0.5515 | No |
| 23 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 2355 | 0.072 | 0.5412 | No |
| 24 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 2902 | 0.057 | 0.5072 | No |
| 25 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 3055 | 0.053 | 0.5023 | No |
| 26 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 3261 | 0.048 | 0.4928 | No |
| 27 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 3402 | 0.045 | 0.4878 | No |
| 28 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 4037 | 0.032 | 0.4441 | No |
| 29 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4885 | 0.017 | 0.3825 | No |
| 30 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 5350 | 0.009 | 0.3487 | No |
| 31 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 5402 | 0.009 | 0.3460 | No |
| 32 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 5862 | 0.002 | 0.3117 | No |
| 33 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 7828 | -0.028 | 0.1673 | No |
| 34 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 7950 | -0.030 | 0.1619 | No |
| 35 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 7953 | -0.030 | 0.1655 | No |
| 36 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 9273 | -0.052 | 0.0727 | No |
| 37 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 9459 | -0.055 | 0.0656 | No |
| 38 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 9637 | -0.058 | 0.0595 | No |
| 39 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 10574 | -0.079 | -0.0011 | No |
| 40 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 10785 | -0.085 | -0.0065 | No |
| 41 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 11357 | -0.101 | -0.0370 | No |
| 42 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 12080 | -0.131 | -0.0752 | No |
| 43 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12857 | -0.193 | -0.1098 | No |
| 44 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 12923 | -0.203 | -0.0897 | No |
| 45 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 13137 | -0.265 | -0.0731 | No |
| 46 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13331 | -0.718 | 0.0008 | No |
