Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LIPID_CATABOLIC_PROCESS |
| Enrichment Score (ES) | 0.76578116 |
| Normalized Enrichment Score (NES) | 2.1537447 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.5371627E-4 |
| FWER p-Value | 0.01 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 47 | 0.660 | 0.1656 | Yes |
| 2 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 54 | 0.630 | 0.3266 | Yes |
| 3 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 181 | 0.405 | 0.4210 | Yes |
| 4 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 253 | 0.340 | 0.5027 | Yes |
| 5 | STS | STS Entrez, Source | steroid sulfatase (microsomal), arylsulfatase C, isozyme S | 288 | 0.316 | 0.5812 | Yes |
| 6 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 585 | 0.209 | 0.6124 | Yes |
| 7 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 810 | 0.168 | 0.6386 | Yes |
| 8 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 839 | 0.164 | 0.6786 | Yes |
| 9 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1025 | 0.145 | 0.7017 | Yes |
| 10 | LYPLA3 | LYPLA3 Entrez, Source | lysophospholipase 3 (lysosomal phospholipase A2) | 1075 | 0.138 | 0.7335 | Yes |
| 11 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1126 | 0.134 | 0.7641 | Yes |
| 12 | SMPD3 | SMPD3 Entrez, Source | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 1478 | 0.109 | 0.7658 | Yes |
| 13 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 2210 | 0.077 | 0.7306 | No |
| 14 | CEL | CEL Entrez, Source | carboxyl ester lipase (bile salt-stimulated lipase) | 2522 | 0.067 | 0.7244 | No |
| 15 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 2591 | 0.065 | 0.7360 | No |
| 16 | ACADVL | ACADVL Entrez, Source | acyl-Coenzyme A dehydrogenase, very long chain | 4485 | 0.024 | 0.6000 | No |
| 17 | PRDX6 | PRDX6 Entrez, Source | peroxiredoxin 6 | 4787 | 0.019 | 0.5821 | No |
| 18 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4941 | 0.016 | 0.5748 | No |
| 19 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 5260 | 0.011 | 0.5537 | No |
| 20 | NEU3 | NEU3 Entrez, Source | sialidase 3 (membrane sialidase) | 6050 | -0.001 | 0.4946 | No |
| 21 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 6362 | -0.006 | 0.4727 | No |
| 22 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 6649 | -0.010 | 0.4537 | No |
| 23 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 9075 | -0.048 | 0.2841 | No |
| 24 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 12287 | -0.141 | 0.0792 | No |
