Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetLI_FETAL_VS_WT_KIDNEY_UP
Enrichment Score (ES)0.54608524
Normalized Enrichment Score (NES)2.0141213
Nominal p-value0.0
FDR q-value0.0039317543
FWER p-Value0.168
Table: GSEA Results Summary



Fig 1: Enrichment plot: LI_FETAL_VS_WT_KIDNEY_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 721.2540.0778Yes
2COL1A2COL1A2
Entrez,  Source
collagen, type I, alpha 261.1540.1492Yes
3DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)180.7970.1979Yes
4MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)430.6750.2380Yes
5CRYABCRYAB
Entrez,  Source
crystallin, alpha B1060.4940.2640Yes
6PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)1410.4550.2898Yes
7AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)2550.3380.3022Yes
8CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 12570.3370.3231Yes
9ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)2980.3100.3393Yes
10TFPITFPI
Entrez,  Source
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)3160.2940.3563Yes
11SLC22A5SLC22A5
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 53450.2850.3719Yes
12TPST1TPST1
Entrez,  Source
tyrosylprotein sulfotransferase 14180.2540.3822Yes
13HERPUD1HERPUD1
Entrez,  Source
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 14480.2450.3952Yes
14LEPRLEPR
Entrez,  Source
leptin receptor4710.2370.4083Yes
15ALCAMALCAM
Entrez,  Source
activated leukocyte cell adhesion molecule5390.2190.4168Yes
16TSPOTSPO
Entrez,  Source
translocator protein (18kDa)6440.1980.4213Yes
17SCP2SCP2
Entrez,  Source
sterol carrier protein 27260.1810.4264Yes
18ANXA4ANXA4
Entrez,  Source
annexin A47360.1790.4368Yes
19ALDH1A1ALDH1A1
Entrez,  Source
aldehyde dehydrogenase 1 family, member A17390.1780.4478Yes
20CREBL2CREBL2
Entrez,  Source
cAMP responsive element binding protein-like 27640.1750.4568Yes
21CLDN3CLDN3
Entrez,  Source
claudin 37880.1720.4658Yes
22TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 28020.1690.4753Yes
23CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)8170.1670.4846Yes
24CX3CL1CX3CL1
Entrez,  Source
chemokine (C-X3-C motif) ligand 18370.1640.4934Yes
25SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 410650.1390.4849Yes
26APOMAPOM
Entrez,  Source
apolipoprotein M10740.1380.4929Yes
27KIFC3KIFC3
Entrez,  Source
kinesin family member C310870.1370.5005Yes
28CASTCAST
Entrez,  Source
calpastatin10900.1370.5089Yes
29PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)11610.1310.5118Yes
30ANXA3ANXA3
Entrez,  Source
annexin A311700.1310.5193Yes
31CAV2CAV2
Entrez,  Source
caveolin 211860.1290.5262Yes
32TGOLN2TGOLN2
Entrez,  Source
trans-golgi network protein 212800.1210.5267Yes
33ASAH1ASAH1
Entrez,  Source
N-acylsphingosine amidohydrolase (acid ceramidase) 113100.1190.5319Yes
34AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase13730.1150.5344Yes
35HRSP12HRSP12
Entrez,  Source
heat-responsive protein 1214830.1090.5330Yes
36ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A115850.1030.5317Yes
37FGFR3FGFR3
Entrez,  Source
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)16670.0990.5318Yes
38LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 217440.0950.5320Yes
39SPP1SPP1
Entrez,  Source
secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)17760.0940.5355Yes
40MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase18080.0920.5389Yes
41PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 718470.0910.5416Yes
42SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A18630.0900.5461Yes
43CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta19770.0860.5429No
44APOEAPOE
Entrez,  Source
apolipoprotein E21230.0800.5369No
45HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)21410.0790.5405No
46ACSL1ACSL1
Entrez,  Source
acyl-CoA synthetase long-chain family member 123550.0720.5289No
47FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)23880.0710.5309No
48ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide23950.0710.5349No
49CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)24920.0680.5319No
50CTSHCTSH
Entrez,  Source
cathepsin H27230.0620.5183No
51UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase27790.0610.5179No
52ANGPT1ANGPT1
Entrez,  Source
angiopoietin 127820.0610.5216No
53IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 228440.0590.5206No
54ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)29350.0570.5173No
55S100A10S100A10
Entrez,  Source
S100 calcium binding protein A1029810.0550.5173No
56ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b30810.0520.5131No
57PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A32160.0490.5060No
58CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)32960.0470.5030No
59ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)34120.0450.4971No
60IL1R1IL1R1
Entrez,  Source
interleukin 1 receptor, type I35400.0420.4901No
61FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase35470.0420.4923No
62KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)35670.0410.4934No
63SEPP1SEPP1
Entrez,  Source
selenoprotein P, plasma, 136250.0400.4916No
64CLUCLU
Entrez,  Source
clusterin37390.0380.4854No
65SDHDSDHD
Entrez,  Source
succinate dehydrogenase complex, subunit D, integral membrane protein38520.0360.4792No
66ATP1A1ATP1A1
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 1 polypeptide40720.0310.4646No
67SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 241810.0290.4582No
68SYNGR2SYNGR2
Entrez,  Source
synaptogyrin 242230.0290.4569No
69DYNC2LI1DYNC2LI1
Entrez,  Source
dynein, cytoplasmic 2, light intermediate chain 142570.0280.4562No
70BPGMBPGM
Entrez,  Source
2,3-bisphosphoglycerate mutase43440.0260.4513No
71SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 146970.0200.4260No
72PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)47950.0190.4198No
73PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A51330.0130.3951No
74NR3C1NR3C1
Entrez,  Source
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)52270.0110.3888No
75GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 352320.0110.3892No
76CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)57040.0040.3538No
77TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 557410.0040.3513No
78DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)58150.0030.3460No
79SERINC5SERINC5
Entrez,  Source
serine incorporator 56205-0.0030.3168No
80AGRINAGRIN
Entrez,  Source
agrin6677-0.0100.2818No
81TCF21TCF21
Entrez,  Source
transcription factor 216717-0.0110.2796No
82PMP22PMP22
Entrez,  Source
peripheral myelin protein 226796-0.0120.2744No
83FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C7017-0.0150.2587No
84PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 27026-0.0160.2591No
85ITM2BITM2B
Entrez,  Source
integral membrane protein 2B8067-0.0320.1825No
86ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)8198-0.0340.1748No
87ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 68734-0.0430.1370No
88LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog9007-0.0470.1194No
89IFIT1IFIT1
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 19511-0.0560.0849No
90GNG12GNG12
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 129681-0.0590.0758No
91GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha10152-0.0690.0446No
92SLC35A3SLC35A3
Entrez,  Source
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A310237-0.0710.0426No
93TOB1TOB1
Entrez,  Source
transducer of ERBB2, 110294-0.0720.0429No
94DUSP9DUSP9
Entrez,  Source
dual specificity phosphatase 910581-0.0790.0262No
95TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)10602-0.0800.0297No
96TACSTD2TACSTD2
Entrez,  Source
tumor-associated calcium signal transducer 211118-0.094-0.0034No
97VEGFVEGF
Entrez,  Source
vascular endothelial growth factor11386-0.102-0.0173No
98MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 211574-0.108-0.0247No
99MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle11636-0.111-0.0224No
100GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 111660-0.111-0.0172No
101NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 311864-0.120-0.0251No
102PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase11891-0.121-0.0195No
103SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11986-0.126-0.0188No
104VLDLRVLDLR
Entrez,  Source
very low density lipoprotein receptor12037-0.128-0.0146No
105XBP1XBP1
Entrez,  Source
X-box binding protein 112147-0.134-0.0146No
106PODXLPODXL
Entrez,  Source
podocalyxin-like12264-0.140-0.0146No
107GNG11GNG11
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 1113005-0.219-0.0569No
108PRPS2PRPS2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase 213109-0.256-0.0488No
109SLC30A1SLC30A1
Entrez,  Source
solute carrier family 30 (zinc transporter), member 113129-0.260-0.0341No
110ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 313235-0.330-0.0215No
111PPP1R3CPPP1R3C
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 3C13309-0.4750.0025No
Table: GSEA details [plain text format]



Fig 2: LI_FETAL_VS_WT_KIDNEY_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: LI_FETAL_VS_WT_KIDNEY_UP: Random ES distribution   
Gene set null distribution of ES for LI_FETAL_VS_WT_KIDNEY_UP