Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | MOREAUX_TACI_HI_VS_LOW_DN |
| Enrichment Score (ES) | -0.6001632 |
| Normalized Enrichment Score (NES) | -2.1670291 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.9033842E-4 |
| FWER p-Value | 0.0040 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IHPK2 | IHPK2 Entrez, Source | inositol hexaphosphate kinase 2 | 536 | 0.219 | -0.0073 | No |
| 2 | IREB2 | IREB2 Entrez, Source | iron-responsive element binding protein 2 | 847 | 0.163 | -0.0062 | No |
| 3 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 1344 | 0.117 | -0.0259 | No |
| 4 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 1841 | 0.091 | -0.0496 | No |
| 5 | TRIB1 | TRIB1 Entrez, Source | tribbles homolog 1 (Drosophila) | 2792 | 0.060 | -0.1120 | No |
| 6 | MINPP1 | MINPP1 Entrez, Source | multiple inositol polyphosphate histidine phosphatase, 1 | 2918 | 0.057 | -0.1129 | No |
| 7 | TMEM165 | TMEM165 Entrez, Source | transmembrane protein 165 | 3074 | 0.052 | -0.1166 | No |
| 8 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 3796 | 0.037 | -0.1654 | No |
| 9 | PSMC4 | PSMC4 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 4541 | 0.022 | -0.2181 | No |
| 10 | FIBP | FIBP Entrez, Source | fibroblast growth factor (acidic) intracellular binding protein | 4881 | 0.017 | -0.2410 | No |
| 11 | SLC33A1 | SLC33A1 Entrez, Source | solute carrier family 33 (acetyl-CoA transporter), member 1 | 4893 | 0.017 | -0.2393 | No |
| 12 | WDR61 | WDR61 Entrez, Source | WD repeat domain 61 | 5633 | 0.005 | -0.2942 | No |
| 13 | NMT1 | NMT1 Entrez, Source | N-myristoyltransferase 1 | 5907 | 0.001 | -0.3145 | No |
| 14 | KEAP1 | KEAP1 Entrez, Source | kelch-like ECH-associated protein 1 | 6022 | -0.000 | -0.3230 | No |
| 15 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 6406 | -0.006 | -0.3509 | No |
| 16 | NCLN | NCLN Entrez, Source | nicalin homolog (zebrafish) | 6432 | -0.007 | -0.3518 | No |
| 17 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 6475 | -0.007 | -0.3539 | No |
| 18 | C3ORF64 | C3ORF64 Entrez, Source | chromosome 3 open reading frame 64 | 6713 | -0.011 | -0.3701 | No |
| 19 | UPF3A | UPF3A Entrez, Source | UPF3 regulator of nonsense transcripts homolog A (yeast) | 7486 | -0.022 | -0.4249 | No |
| 20 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 7696 | -0.026 | -0.4367 | No |
| 21 | STAM2 | STAM2 Entrez, Source | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 7791 | -0.027 | -0.4397 | No |
| 22 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 8409 | -0.037 | -0.4805 | No |
| 23 | G3BP | G3BP Entrez, Source | - | 8799 | -0.044 | -0.5032 | No |
| 24 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 8812 | -0.044 | -0.4974 | No |
| 25 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 9367 | -0.054 | -0.5311 | No |
| 26 | IK | IK Entrez, Source | IK cytokine, down-regulator of HLA II | 9896 | -0.064 | -0.5612 | No |
| 27 | BTBD1 | BTBD1 Entrez, Source | BTB (POZ) domain containing 1 | 10176 | -0.070 | -0.5716 | No |
| 28 | CCT2 | CCT2 Entrez, Source | chaperonin containing TCP1, subunit 2 (beta) | 10334 | -0.073 | -0.5724 | No |
| 29 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 10355 | -0.074 | -0.5628 | No |
| 30 | ZCCHC10 | ZCCHC10 Entrez, Source | zinc finger, CCHC domain containing 10 | 10727 | -0.083 | -0.5781 | No |
| 31 | C1QBP | C1QBP Entrez, Source | complement component 1, q subcomponent binding protein | 10991 | -0.090 | -0.5843 | No |
| 32 | THYN1 | THYN1 Entrez, Source | thymocyte nuclear protein 1 | 11202 | -0.096 | -0.5857 | Yes |
| 33 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11229 | -0.096 | -0.5731 | Yes |
| 34 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11362 | -0.101 | -0.5679 | Yes |
| 35 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 11401 | -0.102 | -0.5553 | Yes |
| 36 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 11472 | -0.105 | -0.5448 | Yes |
| 37 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 11559 | -0.108 | -0.5350 | Yes |
| 38 | IFT74 | IFT74 Entrez, Source | intraflagellar transport 74 homolog (Chlamydomonas) | 11592 | -0.109 | -0.5210 | Yes |
| 39 | ACTL6A | ACTL6A Entrez, Source | actin-like 6A | 11816 | -0.118 | -0.5200 | Yes |
| 40 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 11852 | -0.119 | -0.5047 | Yes |
| 41 | DDX18 | DDX18 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 11900 | -0.122 | -0.4899 | Yes |
| 42 | MATR3 | MATR3 Entrez, Source | matrin 3 | 11949 | -0.124 | -0.4748 | Yes |
| 43 | TAF2 | TAF2 Entrez, Source | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 12029 | -0.128 | -0.4615 | Yes |
| 44 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 12073 | -0.130 | -0.4451 | Yes |
| 45 | EIF3S4 | EIF3S4 Entrez, Source | eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa | 12079 | -0.131 | -0.4258 | Yes |
| 46 | DARS | DARS Entrez, Source | aspartyl-tRNA synthetase | 12158 | -0.134 | -0.4114 | Yes |
| 47 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 12162 | -0.135 | -0.3913 | Yes |
| 48 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12217 | -0.137 | -0.3746 | Yes |
| 49 | RUVBL2 | RUVBL2 Entrez, Source | RuvB-like 2 (E. coli) | 12316 | -0.144 | -0.3603 | Yes |
| 50 | NUDT5 | NUDT5 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 5 | 12409 | -0.149 | -0.3448 | Yes |
| 51 | PAPD4 | PAPD4 Entrez, Source | PAP associated domain containing 4 | 12421 | -0.150 | -0.3231 | Yes |
| 52 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 12459 | -0.152 | -0.3030 | Yes |
| 53 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12611 | -0.164 | -0.2896 | Yes |
| 54 | GLT8D1 | GLT8D1 Entrez, Source | glycosyltransferase 8 domain containing 1 | 12626 | -0.166 | -0.2657 | Yes |
| 55 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 12697 | -0.173 | -0.2449 | Yes |
| 56 | MINA | MINA Entrez, Source | MYC induced nuclear antigen | 12713 | -0.175 | -0.2197 | Yes |
| 57 | LAP3 | LAP3 Entrez, Source | leucine aminopeptidase 3 | 12799 | -0.185 | -0.1982 | Yes |
| 58 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 12803 | -0.186 | -0.1704 | Yes |
| 59 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 12812 | -0.187 | -0.1428 | Yes |
| 60 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 12950 | -0.209 | -0.1216 | Yes |
| 61 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 13031 | -0.226 | -0.0936 | Yes |
| 62 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 13043 | -0.231 | -0.0596 | Yes |
| 63 | NUDCD2 | NUDCD2 Entrez, Source | NudC domain containing 2 | 13145 | -0.267 | -0.0269 | Yes |
| 64 | CCDC5 | CCDC5 Entrez, Source | coiled-coil domain containing 5 (spindle associated) | 13162 | -0.277 | 0.0136 | Yes |
