Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | MRNA_PROCESSING_GO_0006397 |
| Enrichment Score (ES) | -0.58024424 |
| Normalized Enrichment Score (NES) | -1.8189054 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.043018803 |
| FWER p-Value | 0.847 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1181 | 0.130 | -0.0483 | No |
| 2 | GRSF1 | GRSF1 Entrez, Source | G-rich RNA sequence binding factor 1 | 3661 | 0.040 | -0.2223 | No |
| 3 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 4725 | 0.020 | -0.2960 | No |
| 4 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.4228 | No |
| 5 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 7294 | -0.019 | -0.4807 | No |
| 6 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7495 | -0.022 | -0.4888 | No |
| 7 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7935 | -0.030 | -0.5125 | No |
| 8 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7938 | -0.030 | -0.5034 | No |
| 9 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7939 | -0.030 | -0.4941 | No |
| 10 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 8375 | -0.037 | -0.5152 | No |
| 11 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8466 | -0.038 | -0.5100 | No |
| 12 | SLU7 | SLU7 Entrez, Source | - | 8831 | -0.044 | -0.5235 | No |
| 13 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 8886 | -0.045 | -0.5135 | No |
| 14 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 9516 | -0.056 | -0.5432 | No |
| 15 | GEMIN6 | GEMIN6 Entrez, Source | gem (nuclear organelle) associated protein 6 | 9841 | -0.063 | -0.5479 | No |
| 16 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10104 | -0.068 | -0.5463 | No |
| 17 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 10557 | -0.079 | -0.5556 | Yes |
| 18 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.5399 | Yes |
| 19 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11050 | -0.092 | -0.5382 | Yes |
| 20 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 11058 | -0.092 | -0.5100 | Yes |
| 21 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.4955 | Yes |
| 22 | EFTUD2 | EFTUD2 Entrez, Source | elongation factor Tu GTP binding domain containing 2 | 11362 | -0.101 | -0.4708 | Yes |
| 23 | CRNKL1 | CRNKL1 Entrez, Source | Crn, crooked neck-like 1 (Drosophila) | 11540 | -0.107 | -0.4508 | Yes |
| 24 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12128 | -0.133 | -0.4534 | Yes |
| 25 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 12190 | -0.136 | -0.4155 | Yes |
| 26 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 12267 | -0.140 | -0.3774 | Yes |
| 27 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12406 | -0.149 | -0.3413 | Yes |
| 28 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12418 | -0.149 | -0.2956 | Yes |
| 29 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 12424 | -0.150 | -0.2492 | Yes |
| 30 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12437 | -0.150 | -0.2032 | Yes |
| 31 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.1622 | Yes |
| 32 | DDX39 | DDX39 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 | 12889 | -0.198 | -0.1258 | Yes |
| 33 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12913 | -0.201 | -0.0647 | Yes |
| 34 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 13213 | -0.310 | 0.0097 | Yes |
