Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | MRNA_PROCESSING_REACTOME |
| Enrichment Score (ES) | -0.60176563 |
| Normalized Enrichment Score (NES) | -2.1450741 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.336448E-4 |
| FWER p-Value | 0.01 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 2451 | 0.069 | -0.1710 | No |
| 2 | SF4 | SF4 Entrez, Source | splicing factor 4 | 2755 | 0.061 | -0.1819 | No |
| 3 | SUPT5H | SUPT5H Entrez, Source | suppressor of Ty 5 homolog (S. cerevisiae) | 4387 | 0.026 | -0.2997 | No |
| 4 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 4725 | 0.020 | -0.3213 | No |
| 5 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4726 | 0.020 | -0.3175 | No |
| 6 | HNRPA3 | HNRPA3 Entrez, Source | heterogeneous nuclear ribonucleoprotein A3 | 5026 | 0.015 | -0.3371 | No |
| 7 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 5146 | 0.012 | -0.3437 | No |
| 8 | SF3B1 | SF3B1 Entrez, Source | splicing factor 3b, subunit 1, 155kDa | 5416 | 0.009 | -0.3622 | No |
| 9 | DNAJC8 | DNAJC8 Entrez, Source | DnaJ (Hsp40) homolog, subfamily C, member 8 | 5671 | 0.005 | -0.3805 | No |
| 10 | PRPF4B | PRPF4B Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | 5699 | 0.004 | -0.3817 | No |
| 11 | GIPC1 | GIPC1 Entrez, Source | GIPC PDZ domain containing family, member 1 | 6006 | -0.000 | -0.4047 | No |
| 12 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 6322 | -0.005 | -0.4274 | No |
| 13 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 6368 | -0.006 | -0.4296 | No |
| 14 | PHF5A | PHF5A Entrez, Source | PHD finger protein 5A | 6441 | -0.007 | -0.4338 | No |
| 15 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 6904 | -0.014 | -0.4659 | No |
| 16 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 7294 | -0.019 | -0.4914 | No |
| 17 | CLK4 | CLK4 Entrez, Source | CDC-like kinase 4 | 7341 | -0.020 | -0.4909 | No |
| 18 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 7495 | -0.022 | -0.4981 | No |
| 19 | SF3A2 | SF3A2 Entrez, Source | splicing factor 3a, subunit 2, 66kDa | 7935 | -0.030 | -0.5254 | No |
| 20 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 7938 | -0.030 | -0.5197 | No |
| 21 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 7939 | -0.030 | -0.5140 | No |
| 22 | DHX16 | DHX16 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 7988 | -0.031 | -0.5116 | No |
| 23 | CPSF3 | CPSF3 Entrez, Source | cleavage and polyadenylation specific factor 3, 73kDa | 8375 | -0.037 | -0.5335 | No |
| 24 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 8466 | -0.038 | -0.5328 | No |
| 25 | RBM5 | RBM5 Entrez, Source | RNA binding motif protein 5 | 8977 | -0.047 | -0.5620 | No |
| 26 | RNPS1 | RNPS1 Entrez, Source | RNA binding protein S1, serine-rich domain | 9038 | -0.048 | -0.5573 | No |
| 27 | SNRPN | SNRPN Entrez, Source | small nuclear ribonucleoprotein polypeptide N | 9094 | -0.049 | -0.5519 | No |
| 28 | PPM1G | PPM1G Entrez, Source | protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform | 9450 | -0.055 | -0.5679 | No |
| 29 | DHX8 | DHX8 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 9578 | -0.057 | -0.5663 | No |
| 30 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 9722 | -0.060 | -0.5654 | No |
| 31 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10104 | -0.068 | -0.5807 | No |
| 32 | PRPF4 | PRPF4 Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog (yeast) | 10359 | -0.074 | -0.5855 | No |
| 33 | NXF1 | NXF1 Entrez, Source | nuclear RNA export factor 1 | 10576 | -0.079 | -0.5863 | Yes |
| 34 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.5789 | Yes |
| 35 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 10867 | -0.087 | -0.5751 | Yes |
| 36 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 10937 | -0.089 | -0.5630 | Yes |
| 37 | RNMT | RNMT Entrez, Source | RNA (guanine-7-) methyltransferase | 11050 | -0.092 | -0.5536 | Yes |
| 38 | HNRPL | HNRPL Entrez, Source | heterogeneous nuclear ribonucleoprotein L | 11160 | -0.095 | -0.5433 | Yes |
| 39 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 11272 | -0.098 | -0.5327 | Yes |
| 40 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 11401 | -0.102 | -0.5225 | Yes |
| 41 | METTL3 | METTL3 Entrez, Source | methyltransferase like 3 | 11454 | -0.104 | -0.5061 | Yes |
| 42 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11569 | -0.108 | -0.4936 | Yes |
| 43 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 11613 | -0.110 | -0.4755 | Yes |
| 44 | SNRPN /// SNURF | 11623 | -0.110 | -0.4547 | Yes | ||
| 45 | HNRPC | HNRPC Entrez, Source | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 11740 | -0.115 | -0.4412 | Yes |
| 46 | RBM17 | RBM17 Entrez, Source | RNA binding motif protein 17 | 11745 | -0.115 | -0.4192 | Yes |
| 47 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 12128 | -0.133 | -0.4221 | Yes |
| 48 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 12162 | -0.135 | -0.3984 | Yes |
| 49 | NCBP1 | NCBP1 Entrez, Source | nuclear cap binding protein subunit 1, 80kDa | 12406 | -0.149 | -0.3877 | Yes |
| 50 | CSTF1 | CSTF1 Entrez, Source | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | 12418 | -0.149 | -0.3595 | Yes |
| 51 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 12424 | -0.150 | -0.3307 | Yes |
| 52 | DDX20 | DDX20 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 | 12437 | -0.150 | -0.3023 | Yes |
| 53 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 12549 | -0.158 | -0.2799 | Yes |
| 54 | PTBP2 | PTBP2 Entrez, Source | polypyrimidine tract binding protein 2 | 12573 | -0.160 | -0.2505 | Yes |
| 55 | HNRPH1 | HNRPH1 Entrez, Source | heterogeneous nuclear ribonucleoprotein H1 (H) | 12830 | -0.189 | -0.2330 | Yes |
| 56 | HNRPU | HNRPU Entrez, Source | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 12874 | -0.196 | -0.1981 | Yes |
| 57 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 12913 | -0.201 | -0.1618 | Yes |
| 58 | DICER1 | DICER1 Entrez, Source | Dicer1, Dcr-1 homolog (Drosophila) | 12970 | -0.213 | -0.1245 | Yes |
| 59 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 13076 | -0.242 | -0.0854 | Yes |
| 60 | FUS | FUS Entrez, Source | fusion (involved in t(12;16) in malignant liposarcoma) | 13100 | -0.252 | -0.0381 | Yes |
| 61 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 13182 | -0.289 | 0.0120 | Yes |
