Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | M_PHASE |
| Enrichment Score (ES) | -0.40611207 |
| Normalized Enrichment Score (NES) | -1.4147316 |
| Nominal p-value | 0.032941177 |
| FDR q-value | 0.32993713 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 821 | 0.166 | -0.0215 | No |
| 2 | NPM2 | NPM2 Entrez, Source | nucleophosmin/nucleoplasmin, 2 | 1422 | 0.112 | -0.0396 | No |
| 3 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 1773 | 0.094 | -0.0431 | No |
| 4 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 2430 | 0.070 | -0.0755 | No |
| 5 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 2485 | 0.069 | -0.0630 | No |
| 6 | STAG3 | STAG3 Entrez, Source | stromal antigen 3 | 2752 | 0.061 | -0.0682 | No |
| 7 | EREG | EREG Entrez, Source | epiregulin | 3011 | 0.054 | -0.0745 | No |
| 8 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 3116 | 0.051 | -0.0699 | No |
| 9 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 3333 | 0.046 | -0.0749 | No |
| 10 | DUSP13 | DUSP13 Entrez, Source | dual specificity phosphatase 13 | 4468 | 0.024 | -0.1544 | No |
| 11 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 4592 | 0.022 | -0.1584 | No |
| 12 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 4680 | 0.020 | -0.1600 | No |
| 13 | PPP5C | PPP5C Entrez, Source | protein phosphatase 5, catalytic subunit | 5131 | 0.013 | -0.1908 | No |
| 14 | SYCP1 | SYCP1 Entrez, Source | synaptonemal complex protein 1 | 5530 | 0.007 | -0.2191 | No |
| 15 | NBN | NBN Entrez, Source | nibrin | 5580 | 0.006 | -0.2213 | No |
| 16 | CHFR | CHFR Entrez, Source | checkpoint with forkhead and ring finger domains | 6104 | -0.002 | -0.2602 | No |
| 17 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 7015 | -0.015 | -0.3250 | No |
| 18 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 7286 | -0.019 | -0.3406 | No |
| 19 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 7811 | -0.028 | -0.3734 | No |
| 20 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 7928 | -0.030 | -0.3750 | No |
| 21 | ZWINT | ZWINT Entrez, Source | ZW10 interactor | 8148 | -0.033 | -0.3835 | No |
| 22 | TTN | TTN Entrez, Source | titin | 8450 | -0.038 | -0.3969 | Yes |
| 23 | SC65 | SC65 Entrez, Source | - | 8463 | -0.038 | -0.3885 | Yes |
| 24 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 8469 | -0.038 | -0.3796 | Yes |
| 25 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 8711 | -0.042 | -0.3875 | Yes |
| 26 | NEK6 | NEK6 Entrez, Source | NIMA (never in mitosis gene a)-related kinase 6 | 8774 | -0.043 | -0.3816 | Yes |
| 27 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 8812 | -0.044 | -0.3738 | Yes |
| 28 | ANAPC4 | ANAPC4 Entrez, Source | anaphase promoting complex subunit 4 | 8855 | -0.045 | -0.3661 | Yes |
| 29 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 8927 | -0.046 | -0.3603 | Yes |
| 30 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 8995 | -0.047 | -0.3539 | Yes |
| 31 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 9367 | -0.054 | -0.3689 | Yes |
| 32 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 9814 | -0.062 | -0.3873 | Yes |
| 33 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 9872 | -0.064 | -0.3762 | Yes |
| 34 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 10056 | -0.067 | -0.3737 | Yes |
| 35 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 10069 | -0.068 | -0.3581 | Yes |
| 36 | SUGT1 | SUGT1 Entrez, Source | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 10151 | -0.069 | -0.3475 | Yes |
| 37 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 10523 | -0.078 | -0.3564 | Yes |
| 38 | AKAP8 | AKAP8 Entrez, Source | A kinase (PRKA) anchor protein 8 | 10573 | -0.079 | -0.3409 | Yes |
| 39 | CETN1 | CETN1 Entrez, Source | centrin, EF-hand protein, 1 | 10779 | -0.085 | -0.3359 | Yes |
| 40 | LIG3 | LIG3 Entrez, Source | ligase III, DNA, ATP-dependent | 10864 | -0.087 | -0.3211 | Yes |
| 41 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 11218 | -0.096 | -0.3244 | Yes |
| 42 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 11559 | -0.108 | -0.3238 | Yes |
| 43 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 11748 | -0.115 | -0.3102 | Yes |
| 44 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12066 | -0.130 | -0.3027 | Yes |
| 45 | CD28 | CD28 Entrez, Source | CD28 molecule | 12234 | -0.138 | -0.2818 | Yes |
| 46 | MAD2L2 | MAD2L2 Entrez, Source | MAD2 mitotic arrest deficient-like 2 (yeast) | 12256 | -0.140 | -0.2495 | Yes |
| 47 | TARDBP | TARDBP Entrez, Source | TAR DNA binding protein | 12292 | -0.142 | -0.2178 | Yes |
| 48 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 12364 | -0.147 | -0.1877 | Yes |
| 49 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 12571 | -0.160 | -0.1645 | Yes |
| 50 | AURKA | AURKA Entrez, Source | aurora kinase A | 12673 | -0.170 | -0.1309 | Yes |
| 51 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12819 | -0.188 | -0.0963 | Yes |
| 52 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.0574 | Yes |
| 53 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 13244 | -0.339 | 0.0074 | Yes |
