Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | M_PHASE_OF_MITOTIC_CELL_CYCLE |
| Enrichment Score (ES) | -0.407206 |
| Normalized Enrichment Score (NES) | -1.3509306 |
| Nominal p-value | 0.077922076 |
| FDR q-value | 0.39744055 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 821 | 0.166 | -0.0114 | No |
| 2 | NPM2 | NPM2 Entrez, Source | nucleophosmin/nucleoplasmin, 2 | 1422 | 0.112 | -0.0226 | No |
| 3 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 1773 | 0.094 | -0.0204 | No |
| 4 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 2430 | 0.070 | -0.0486 | No |
| 5 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 2485 | 0.069 | -0.0319 | No |
| 6 | EREG | EREG Entrez, Source | epiregulin | 3011 | 0.054 | -0.0550 | No |
| 7 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 3116 | 0.051 | -0.0473 | No |
| 8 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 4592 | 0.022 | -0.1516 | No |
| 9 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 4680 | 0.020 | -0.1520 | No |
| 10 | PPP5C | PPP5C Entrez, Source | protein phosphatase 5, catalytic subunit | 5131 | 0.013 | -0.1819 | No |
| 11 | NBN | NBN Entrez, Source | nibrin | 5580 | 0.006 | -0.2138 | No |
| 12 | CHFR | CHFR Entrez, Source | checkpoint with forkhead and ring finger domains | 6104 | -0.002 | -0.2526 | No |
| 13 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 7015 | -0.015 | -0.3164 | No |
| 14 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 7286 | -0.019 | -0.3308 | No |
| 15 | SMC1A | SMC1A Entrez, Source | structural maintenance of chromosomes 1A | 7928 | -0.030 | -0.3701 | No |
| 16 | ZWINT | ZWINT Entrez, Source | ZW10 interactor | 8148 | -0.033 | -0.3766 | No |
| 17 | TTN | TTN Entrez, Source | titin | 8450 | -0.038 | -0.3877 | No |
| 18 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 8711 | -0.042 | -0.3944 | Yes |
| 19 | NEK6 | NEK6 Entrez, Source | NIMA (never in mitosis gene a)-related kinase 6 | 8774 | -0.043 | -0.3859 | Yes |
| 20 | ANAPC4 | ANAPC4 Entrez, Source | anaphase promoting complex subunit 4 | 8855 | -0.045 | -0.3784 | Yes |
| 21 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 8927 | -0.046 | -0.3698 | Yes |
| 22 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 8995 | -0.047 | -0.3606 | Yes |
| 23 | CDC23 | CDC23 Entrez, Source | CDC23 (cell division cycle 23, yeast, homolog) | 9367 | -0.054 | -0.3722 | Yes |
| 24 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 9814 | -0.062 | -0.3869 | Yes |
| 25 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 9872 | -0.064 | -0.3719 | Yes |
| 26 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 10056 | -0.067 | -0.3653 | Yes |
| 27 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 10069 | -0.068 | -0.3456 | Yes |
| 28 | SUGT1 | SUGT1 Entrez, Source | SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) | 10151 | -0.069 | -0.3307 | Yes |
| 29 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 10523 | -0.078 | -0.3349 | Yes |
| 30 | AKAP8 | AKAP8 Entrez, Source | A kinase (PRKA) anchor protein 8 | 10573 | -0.079 | -0.3146 | Yes |
| 31 | CETN1 | CETN1 Entrez, Source | centrin, EF-hand protein, 1 | 10779 | -0.085 | -0.3044 | Yes |
| 32 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 11218 | -0.096 | -0.3082 | Yes |
| 33 | RAN | RAN Entrez, Source | RAN, member RAS oncogene family | 11559 | -0.108 | -0.3011 | Yes |
| 34 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12066 | -0.130 | -0.2999 | Yes |
| 35 | CD28 | CD28 Entrez, Source | CD28 molecule | 12234 | -0.138 | -0.2706 | Yes |
| 36 | MAD2L2 | MAD2L2 Entrez, Source | MAD2 mitotic arrest deficient-like 2 (yeast) | 12256 | -0.140 | -0.2298 | Yes |
| 37 | TARDBP | TARDBP Entrez, Source | TAR DNA binding protein | 12292 | -0.142 | -0.1895 | Yes |
| 38 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 12364 | -0.147 | -0.1505 | Yes |
| 39 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 12571 | -0.160 | -0.1177 | Yes |
| 40 | AURKA | AURKA Entrez, Source | aurora kinase A | 12673 | -0.170 | -0.0737 | Yes |
| 41 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 12819 | -0.188 | -0.0277 | Yes |
| 42 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | 0.0246 | Yes |
