Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetNETPATH_EGFR1_PATHWAY_UP
Enrichment Score (ES)0.5037028
Normalized Enrichment Score (NES)1.8171833
Nominal p-value0.0
FDR q-value0.022836505
FWER p-Value0.934
Table: GSEA Results Summary



Fig 1: Enrichment plot: NETPATH_EGFR1_PATHWAY_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1VIMVIM
Entrez,  Source
vimentin41.2250.0981Yes
2ANXA1ANXA1
Entrez,  Source
annexin A1110.8840.1686Yes
3CTGFCTGF
Entrez,  Source
connective tissue growth factor270.7570.2282Yes
4CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A770.5600.2695Yes
5GPRC5AGPRC5A
Entrez,  Source
G protein-coupled receptor, family C, group 5, member A780.5590.3144Yes
6EMP1EMP1
Entrez,  Source
epithelial membrane protein 11010.5100.3537Yes
7TAGLNTAGLN
Entrez,  Source
transgelin2500.3440.3701Yes
8IER3IER3
Entrez,  Source
immediate early response 33920.2640.3806Yes
9SLC20A1SLC20A1
Entrez,  Source
solute carrier family 20 (phosphate transporter), member 14840.2320.3924Yes
10ZFP36L2ZFP36L2
Entrez,  Source
zinc finger protein 36, C3H type-like 24980.2280.4097Yes
11MGLLMGLL
Entrez,  Source
monoglyceride lipase5100.2240.4269Yes
12CLDN4CLDN4
Entrez,  Source
claudin 45700.2120.4395Yes
13TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 26590.1950.4485Yes
14EGR1EGR1
Entrez,  Source
early growth response 17560.1760.4554Yes
15SPRY2SPRY2
Entrez,  Source
sprouty homolog 2 (Drosophila)7840.1720.4672Yes
16CAV2CAV2
Entrez,  Source
caveolin 211860.1290.4473Yes
17LIFLIF
Entrez,  Source
leukemia inhibitory factor (cholinergic differentiation factor)12030.1270.4563Yes
18PHLDA1PHLDA1
Entrez,  Source
pleckstrin homology-like domain, family A, member 112210.1260.4651Yes
19TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 212410.1240.4737Yes
20DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 112610.1230.4821Yes
21MMP7MMP7
Entrez,  Source
matrix metallopeptidase 7 (matrilysin, uterine)13420.1170.4854Yes
22DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 615040.1080.4819Yes
23PLK2PLK2
Entrez,  Source
polo-like kinase 2 (Drosophila)15230.1070.4892Yes
24FGFBP1FGFBP1
Entrez,  Source
fibroblast growth factor binding protein 115320.1060.4971Yes
25TGM2TGM2
Entrez,  Source
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)16500.1000.4963Yes
26SPP1SPP1
Entrez,  Source
secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)17760.0940.4944Yes
27ACOT7ACOT7
Entrez,  Source
acyl-CoA thioesterase 718110.0920.4992Yes
28HBEGFHBEGF
Entrez,  Source
heparin-binding EGF-like growth factor18490.0910.5037Yes
29HS3ST1HS3ST1
Entrez,  Source
heparan sulfate (glucosamine) 3-O-sulfotransferase 121720.0780.4857No
30HPCAL1HPCAL1
Entrez,  Source
hippocalcin-like 122240.0760.4880No
31DUSP4DUSP4
Entrez,  Source
dual specificity phosphatase 424000.0710.4804No
32TGFATGFA
Entrez,  Source
transforming growth factor, alpha24300.0700.4839No
33ARAR
Entrez,  Source
androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)24770.0690.4859No
34CDKN1BCDKN1B
Entrez,  Source
cyclin-dependent kinase inhibitor 1B (p27, Kip1)24990.0680.4898No
35MAPTMAPT
Entrez,  Source
microtubule-associated protein tau26380.0640.4845No
36ZYXZYX
Entrez,  Source
zyxin26540.0630.4884No
37CCND1CCND1
Entrez,  Source
cyclin D126680.0630.4925No
38DKK3DKK3
Entrez,  Source
dickkopf homolog 3 (Xenopus laevis)29750.0550.4738No
39PLAURPLAUR
Entrez,  Source
plasminogen activator, urokinase receptor29830.0550.4777No
40EREGEREG
Entrez,  Source
epiregulin30110.0540.4800No
41SDC4SDC4
Entrez,  Source
syndecan 4 (amphiglycan, ryudocan)33850.0450.4555No
42NR4A3NR4A3
Entrez,  Source
nuclear receptor subfamily 4, group A, member 334170.0450.4568No
43CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)35060.0430.4536No
44SAA4SAA4
Entrez,  Source
serum amyloid A4, constitutive40170.0330.4177No
45SNAI1SNAI1
Entrez,  Source
snail homolog 1 (Drosophila)42500.0280.4024No
46AKAP12AKAP12
Entrez,  Source
A kinase (PRKA) anchor protein (gravin) 1242830.0280.4022No
47IL4RIL4R
Entrez,  Source
interleukin 4 receptor44940.0240.3883No
48CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)45580.0220.3853No
49BUB1BBUB1B
Entrez,  Source
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)46800.0200.3778No
50CYCSCYCS
Entrez,  Source
cytochrome c, somatic48880.0170.3635No
51LCN2LCN2
Entrez,  Source
lipocalin 2 (oncogene 24p3)51750.0120.3429No
52TUBG1TUBG1
Entrez,  Source
tubulin, gamma 155400.0070.3160No
53CDC42CDC42
Entrez,  Source
cell division cycle 42 (GTP binding protein, 25kDa)55480.0070.3160No
54CXCL5CXCL5
Entrez,  Source
chemokine (C-X-C motif) ligand 555990.0060.3127No
55GJB2GJB2
Entrez,  Source
gap junction protein, beta 2, 26kDa (connexin 26)56440.0050.3097No
56E2F1E2F1
Entrez,  Source
E2F transcription factor 156690.0050.3083No
57EHD1EHD1
Entrez,  Source
EH-domain containing 157010.0040.3063No
58MT3MT3
Entrez,  Source
metallothionein 3 (growth inhibitory factor (neurotrophic))6193-0.0030.2695No
59ESR1ESR1
Entrez,  Source
estrogen receptor 16300-0.0050.2619No
60MSLNMSLN
Entrez,  Source
mesothelin6641-0.0100.2370No
61CCNCCCNC
Entrez,  Source
cyclin C7174-0.0180.1982No
62PLCG1PLCG1
Entrez,  Source
phospholipase C, gamma 17527-0.0230.1735No
63UBE2NUBE2N
Entrez,  Source
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)7534-0.0230.1749No
64SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 27731-0.0260.1622No
65TMEM97TMEM97
Entrez,  Source
transmembrane protein 977845-0.0280.1559No
66PDLIM4PDLIM4
Entrez,  Source
PDZ and LIM domain 48086-0.0320.1404No
67NOS1NOS1
Entrez,  Source
nitric oxide synthase 1 (neuronal)8645-0.0410.1016No
68PPP2R1APPP2R1A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform8698-0.0420.1010No
69PTHLHPTHLH
Entrez,  Source
parathyroid hormone-like hormone8761-0.0430.0998No
70HPRT1HPRT1
Entrez,  Source
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)8796-0.0440.1007No
71PTGS2PTGS2
Entrez,  Source
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)8937-0.0460.0939No
72PPP1R10PPP1R10
Entrez,  Source
protein phosphatase 1, regulatory subunit 109241-0.0510.0751No
73FASLGFASLG
Entrez,  Source
Fas ligand (TNF superfamily, member 6)9771-0.0610.0401No
74HGFHGF
Entrez,  Source
hepatocyte growth factor (hepapoietin A; scatter factor)9857-0.0630.0387No
75ITGB5ITGB5
Entrez,  Source
integrin, beta 59946-0.0650.0373No
76COMMD10COMMD10
Entrez,  Source
COMM domain containing 109979-0.0660.0402No
77MMP3MMP3
Entrez,  Source
matrix metallopeptidase 3 (stromelysin 1, progelatinase)10103-0.0680.0364No
78GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha10152-0.0690.0384No
79CYP27B1CYP27B1
Entrez,  Source
cytochrome P450, family 27, subfamily B, polypeptide 110490-0.0770.0192No
80UBE2AUBE2A
Entrez,  Source
ubiquitin-conjugating enzyme E2A (RAD6 homolog)10509-0.0780.0241No
81FKBP4FKBP4
Entrez,  Source
FK506 binding protein 4, 59kDa10541-0.0790.0281No
82MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)10547-0.0790.0340No
83HAS2HAS2
Entrez,  Source
hyaluronan synthase 210766-0.0840.0243No
84HNRPKHNRPK
Entrez,  Source
heterogeneous nuclear ribonucleoprotein K10815-0.0860.0276No
85RPL15RPL15
Entrez,  Source
ribosomal protein L1511041-0.0910.0179No
86BZW1BZW1
Entrez,  Source
basic leucine zipper and W2 domains 111133-0.0940.0186No
87VEGFVEGF
Entrez,  Source
vascular endothelial growth factor11386-0.1020.0078No
88HNRPABHNRPAB
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A/B11401-0.1020.0149No
89AREGAREG
Entrez,  Source
amphiregulin (schwannoma-derived growth factor)11612-0.1100.0079No
90PRPS1PRPS1
Entrez,  Source
phosphoribosyl pyrophosphate synthetase 111832-0.1180.0008No
91PLAUPLAU
Entrez,  Source
plasminogen activator, urokinase11891-0.1210.0062No
92AMD1AMD1
Entrez,  Source
adenosylmethionine decarboxylase 112376-0.147-0.0186No
93SOX9SOX9
Entrez,  Source
SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)12407-0.149-0.0089No
94NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)12500-0.155-0.0034No
95METMET
Entrez,  Source
met proto-oncogene (hepatocyte growth factor receptor)12611-0.1640.0015No
96TUBBTUBB
Entrez,  Source
tubulin, beta12909-0.201-0.0049No
97CA2CA2
Entrez,  Source
carbonic anhydrase II12972-0.2130.0076No
98PPATPPAT
Entrez,  Source
phosphoribosyl pyrophosphate amidotransferase13102-0.2530.0181No
Table: GSEA details [plain text format]



Fig 2: NETPATH_EGFR1_PATHWAY_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NETPATH_EGFR1_PATHWAY_UP: Random ES distribution   
Gene set null distribution of ES for NETPATH_EGFR1_PATHWAY_UP