Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NETPATH_IL_3_PATHWAY_UP |
| Enrichment Score (ES) | 0.67778975 |
| Normalized Enrichment Score (NES) | 2.019646 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0037752856 |
| FWER p-Value | 0.154 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 9 | 0.936 | 0.2422 | Yes |
| 2 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 145 | 0.452 | 0.3493 | Yes |
| 3 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 353 | 0.281 | 0.4065 | Yes |
| 4 | CISH | CISH Entrez, Source | cytokine inducible SH2-containing protein | 363 | 0.275 | 0.4771 | Yes |
| 5 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 564 | 0.213 | 0.5174 | Yes |
| 6 | IL6R | IL6R Entrez, Source | interleukin 6 receptor | 761 | 0.176 | 0.5482 | Yes |
| 7 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 821 | 0.166 | 0.5869 | Yes |
| 8 | CCL7 | CCL7 Entrez, Source | chemokine (C-C motif) ligand 7 | 860 | 0.161 | 0.6259 | Yes |
| 9 | IL3RA | IL3RA Entrez, Source | interleukin 3 receptor, alpha (low affinity) | 1013 | 0.146 | 0.6523 | Yes |
| 10 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1197 | 0.128 | 0.6718 | Yes |
| 11 | CSF1 | CSF1 Entrez, Source | colony stimulating factor 1 (macrophage) | 1723 | 0.096 | 0.6573 | Yes |
| 12 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.6778 | Yes |
| 13 | TGFA | TGFA Entrez, Source | transforming growth factor, alpha | 2430 | 0.070 | 0.6469 | No |
| 14 | HBB | HBB Entrez, Source | hemoglobin, beta | 2898 | 0.057 | 0.6267 | No |
| 15 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 3166 | 0.050 | 0.6197 | No |
| 16 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 3428 | 0.044 | 0.6116 | No |
| 17 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 3949 | 0.034 | 0.5813 | No |
| 18 | CD69 | CD69 Entrez, Source | CD69 molecule | 4095 | 0.031 | 0.5784 | No |
| 19 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 4349 | 0.026 | 0.5662 | No |
| 20 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 4552 | 0.022 | 0.5569 | No |
| 21 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 4762 | 0.019 | 0.5461 | No |
| 22 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 5914 | 0.001 | 0.4600 | No |
| 23 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 6298 | -0.005 | 0.4324 | No |
| 24 | CD86 | CD86 Entrez, Source | CD86 molecule | 6302 | -0.005 | 0.4334 | No |
| 25 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6363 | -0.006 | 0.4303 | No |
| 26 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 6591 | -0.009 | 0.4156 | No |
| 27 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 6595 | -0.009 | 0.4177 | No |
| 28 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 6856 | -0.013 | 0.4015 | No |
| 29 | SOCS3 | SOCS3 Entrez, Source | suppressor of cytokine signaling 3 | 7799 | -0.027 | 0.3379 | No |
| 30 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 9679 | -0.059 | 0.2121 | No |
| 31 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | 0.1675 | No |
| 32 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 12606 | -0.164 | 0.0553 | No |
