Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NETPATH_IL_4_PATHWAY_DOWN |
| Enrichment Score (ES) | 0.6068046 |
| Normalized Enrichment Score (NES) | 1.939425 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.008328576 |
| FWER p-Value | 0.431 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VIM | VIM Entrez, Source | vimentin | 4 | 1.225 | 0.1569 | Yes |
| 2 | LPL | LPL Entrez, Source | lipoprotein lipase | 45 | 0.671 | 0.2400 | Yes |
| 3 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 50 | 0.641 | 0.3219 | Yes |
| 4 | LGALS2 | LGALS2 Entrez, Source | lectin, galactoside-binding, soluble, 2 (galectin 2) | 132 | 0.466 | 0.3756 | Yes |
| 5 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 138 | 0.458 | 0.4341 | Yes |
| 6 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 145 | 0.452 | 0.4916 | Yes |
| 7 | CD9 | CD9 Entrez, Source | CD9 molecule | 283 | 0.320 | 0.5224 | Yes |
| 8 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 466 | 0.240 | 0.5395 | Yes |
| 9 | KCNN2 | KCNN2 Entrez, Source | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 | 529 | 0.221 | 0.5632 | Yes |
| 10 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 754 | 0.176 | 0.5690 | Yes |
| 11 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 759 | 0.176 | 0.5913 | Yes |
| 12 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 834 | 0.165 | 0.6068 | Yes |
| 13 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 1210 | 0.127 | 0.5949 | No |
| 14 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.5644 | No |
| 15 | CLTB | CLTB Entrez, Source | clathrin, light chain (Lcb) | 2253 | 0.076 | 0.5383 | No |
| 16 | TLR4 | TLR4 Entrez, Source | toll-like receptor 4 | 2287 | 0.074 | 0.5453 | No |
| 17 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2499 | 0.068 | 0.5382 | No |
| 18 | TLR2 | TLR2 Entrez, Source | toll-like receptor 2 | 2513 | 0.067 | 0.5458 | No |
| 19 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 2773 | 0.061 | 0.5342 | No |
| 20 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 2826 | 0.059 | 0.5379 | No |
| 21 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 2872 | 0.058 | 0.5420 | No |
| 22 | CYSLTR2 | CYSLTR2 Entrez, Source | cysteinyl leukotriene receptor 2 | 3150 | 0.051 | 0.5276 | No |
| 23 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 3347 | 0.046 | 0.5188 | No |
| 24 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | 0.5124 | No |
| 25 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 3854 | 0.036 | 0.4909 | No |
| 26 | NDRG4 | NDRG4 Entrez, Source | NDRG family member 4 | 3991 | 0.033 | 0.4849 | No |
| 27 | LAMA3 | LAMA3 Entrez, Source | laminin, alpha 3 | 4300 | 0.027 | 0.4652 | No |
| 28 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 4658 | 0.021 | 0.4410 | No |
| 29 | KLK6 | KLK6 Entrez, Source | kallikrein 6 (neurosin, zyme) | 5317 | 0.010 | 0.3928 | No |
| 30 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 5682 | 0.005 | 0.3660 | No |
| 31 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 5914 | 0.001 | 0.3487 | No |
| 32 | IL2RA | IL2RA Entrez, Source | interleukin 2 receptor, alpha | 5995 | 0.000 | 0.3427 | No |
| 33 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | 0.2925 | No |
| 34 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 6782 | -0.012 | 0.2865 | No |
| 35 | CHI3L1 | CHI3L1 Entrez, Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 6833 | -0.013 | 0.2844 | No |
| 36 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 6856 | -0.013 | 0.2844 | No |
| 37 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 6909 | -0.014 | 0.2822 | No |
| 38 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 7189 | -0.018 | 0.2636 | No |
| 39 | ITPKB | ITPKB Entrez, Source | inositol 1,4,5-trisphosphate 3-kinase B | 7612 | -0.024 | 0.2349 | No |
| 40 | CHST10 | CHST10 Entrez, Source | carbohydrate sulfotransferase 10 | 7723 | -0.026 | 0.2300 | No |
| 41 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 8747 | -0.043 | 0.1585 | No |
| 42 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 8937 | -0.046 | 0.1502 | No |
| 43 | MFNG | MFNG Entrez, Source | manic fringe homolog (Drosophila) | 9855 | -0.063 | 0.0894 | No |
| 44 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 10103 | -0.068 | 0.0795 | No |
| 45 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 10770 | -0.085 | 0.0403 | No |
| 46 | CAV3 | CAV3 Entrez, Source | caveolin 3 | 10854 | -0.087 | 0.0452 | No |
| 47 | TRPV5 | TRPV5 Entrez, Source | transient receptor potential cation channel, subfamily V, member 5 | 11002 | -0.090 | 0.0457 | No |
| 48 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 11455 | -0.104 | 0.0251 | No |
| 49 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 11466 | -0.105 | 0.0378 | No |
| 50 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 11645 | -0.111 | 0.0386 | No |
| 51 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 12857 | -0.193 | -0.0277 | No |
| 52 | GBP2 | GBP2 Entrez, Source | guanylate binding protein 2, interferon-inducible | 12940 | -0.207 | -0.0074 | No |
| 53 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 13186 | -0.293 | 0.0117 | No |
