Details for gene set NETPATH_IL_4_PATHWAY

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	NETPATH_IL_4_PATHWAY_UP
Enrichment Score (ES)	0.5388633
Normalized Enrichment Score (NES)	2.0247705
Nominal p-value	0.0
FDR q-value	0.0035647259
FWER p-Value	0.143

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	9	0.936	0.0485	Yes
2	ANXA1	ANXA1 Entrez, Source	annexin A1	11	0.884	0.0948	Yes
3	RGS2	RGS2 Entrez, Source	regulator of G-protein signalling 2, 24kDa	25	0.771	0.1343	Yes
4	TIMP2	TIMP2 Entrez, Source	TIMP metallopeptidase inhibitor 2	28	0.756	0.1738	Yes
5	MAF	MAF Entrez, Source	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	43	0.675	0.2082	Yes
6	CYP1A1	CYP1A1 Entrez, Source	cytochrome P450, family 1, subfamily A, polypeptide 1	72	0.571	0.2360	Yes
7	EGR2	EGR2 Entrez, Source	early growth response 2 (Krox-20 homolog, Drosophila)	87	0.537	0.2632	Yes
8	CCL2	CCL2 Entrez, Source	chemokine (C-C motif) ligand 2	145	0.452	0.2826	Yes
9	LOX	LOX Entrez, Source	lysyl oxidase	154	0.441	0.3051	Yes
10	F13A1	F13A1 Entrez, Source	coagulation factor XIII, A1 polypeptide	163	0.430	0.3271	Yes
11	BMP2	BMP2 Entrez, Source	bone morphogenetic protein 2	164	0.430	0.3497	Yes
12	SLC22A4	SLC22A4 Entrez, Source	solute carrier family 22 (organic cation transporter), member 4	189	0.399	0.3688	Yes
13	JAG1	JAG1 Entrez, Source	jagged 1 (Alagille syndrome)	222	0.366	0.3856	Yes
14	CITED2	CITED2 Entrez, Source	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	297	0.311	0.3963	Yes
15	TFPI	TFPI Entrez, Source	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	316	0.294	0.4104	Yes
16	TIMP3	TIMP3 Entrez, Source	TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)	329	0.291	0.4247	Yes
17	CPT2	CPT2 Entrez, Source	carnitine palmitoyltransferase II	351	0.281	0.4379	Yes
18	CYP2E1	CYP2E1 Entrez, Source	cytochrome P450, family 2, subfamily E, polypeptide 1	389	0.265	0.4490	Yes
19	TMOD1	TMOD1 Entrez, Source	tropomodulin 1	395	0.263	0.4624	Yes
20	KLF4	KLF4 Entrez, Source	Kruppel-like factor 4 (gut)	417	0.254	0.4741	Yes
21	ABCD3	ABCD3 Entrez, Source	ATP-binding cassette, sub-family D (ALD), member 3	456	0.243	0.4840	Yes
22	VCAM1	VCAM1 Entrez, Source	vascular cell adhesion molecule 1	516	0.223	0.4913	Yes
23	FKBP5	FKBP5 Entrez, Source	FK506 binding protein 5	666	0.194	0.4902	Yes
24	ARG1	ARG1 Entrez, Source	arginase, liver	704	0.185	0.4971	Yes
25	GUCY1B3	GUCY1B3 Entrez, Source	guanylate cyclase 1, soluble, beta 3	766	0.175	0.5017	Yes
26	IL10	IL10 Entrez, Source	interleukin 10	842	0.163	0.5046	Yes
27	GAS6	GAS6 Entrez, Source	growth arrest-specific 6	883	0.158	0.5098	Yes
28	F3	F3 Entrez, Source	coagulation factor III (thromboplastin, tissue factor)	943	0.152	0.5133	Yes
29	ST8SIA1	ST8SIA1 Entrez, Source	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	1042	0.142	0.5134	Yes
30	GCNT1	GCNT1 Entrez, Source	glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase)	1068	0.139	0.5188	Yes
31	SLC38A1	SLC38A1 Entrez, Source	solute carrier family 38, member 1	1109	0.135	0.5229	Yes
32	AGC1	AGC1 Entrez, Source	aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122)	1118	0.135	0.5293	Yes
33	PSCD1	PSCD1 Entrez, Source	pleckstrin homology, Sec7 and coiled-coil domains 1(cytohesin 1)	1237	0.125	0.5269	Yes
34	PDZK1IP1	PDZK1IP1 Entrez, Source	PDZK1 interacting protein 1	1298	0.120	0.5287	Yes
35	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	1504	0.108	0.5188	Yes
36	BMP4	BMP4 Entrez, Source	bone morphogenetic protein 4	1506	0.108	0.5244	Yes
37	SLC39A8	SLC39A8 Entrez, Source	solute carrier family 39 (zinc transporter), member 8	1573	0.104	0.5249	Yes
38	FBN1	FBN1 Entrez, Source	fibrillin 1	1643	0.100	0.5249	Yes
39	IFNG	IFNG Entrez, Source	interferon, gamma	1653	0.100	0.5295	Yes
40	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	1679	0.098	0.5328	Yes
41	IL2RB	IL2RB Entrez, Source	interleukin 2 receptor, beta	1686	0.098	0.5374	Yes
42	SULF1	SULF1 Entrez, Source	sulfatase 1	1955	0.087	0.5217	Yes
43	ST6GAL1	ST6GAL1 Entrez, Source	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	2013	0.085	0.5218	Yes
44	IL13RA2	IL13RA2 Entrez, Source	interleukin 13 receptor, alpha 2	2018	0.084	0.5260	Yes
45	PTGER2	PTGER2 Entrez, Source	prostaglandin E receptor 2 (subtype EP2), 53kDa	2027	0.084	0.5298	Yes
46	PAWR	PAWR Entrez, Source	PRKC, apoptosis, WT1, regulator	2056	0.083	0.5320	Yes
47	HS3ST1	HS3ST1 Entrez, Source	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	2172	0.078	0.5274	Yes
48	ITGAM	ITGAM Entrez, Source	integrin, alpha M (complement component 3 receptor 3 subunit)	2219	0.077	0.5279	Yes
49	HPCAL1	HPCAL1 Entrez, Source	hippocalcin-like 1	2224	0.076	0.5317	Yes
50	CART1	CART1 Entrez, Source	cartilage paired-class homeoprotein 1	2267	0.075	0.5324	Yes
51	SATB1	SATB1 Entrez, Source	special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)	2276	0.075	0.5357	Yes
52	TLR4	TLR4 Entrez, Source	toll-like receptor 4	2287	0.074	0.5389	Yes
53	SAMSN1	SAMSN1 Entrez, Source	SAM domain, SH3 domain and nuclear localisation signals, 1	2511	0.067	0.5255	No
54	SCGB3A1	SCGB3A1 Entrez, Source	secretoglobin, family 3A, member 1	2640	0.064	0.5192	No
55	FN1	FN1 Entrez, Source	fibronectin 1	2715	0.062	0.5168	No
56	CEBPB	CEBPB Entrez, Source	CCAAT/enhancer binding protein (C/EBP), beta	2848	0.059	0.5099	No
57	JUN	JUN Entrez, Source	jun oncogene	3104	0.052	0.4933	No
58	MAL	MAL Entrez, Source	mal, T-cell differentiation protein	3112	0.052	0.4955	No
59	ATXN1	ATXN1 Entrez, Source	ataxin 1	3197	0.050	0.4918	No
60	ACTN1	ACTN1 Entrez, Source	actinin, alpha 1	3213	0.049	0.4932	No
61	SPINT2	SPINT2 Entrez, Source	serine peptidase inhibitor, Kunitz type, 2	3215	0.049	0.4957	No
62	CASP3	CASP3 Entrez, Source	caspase 3, apoptosis-related cysteine peptidase	3300	0.047	0.4918	No
63	ELL2	ELL2 Entrez, Source	elongation factor, RNA polymerase II, 2	3352	0.046	0.4904	No
64	SERPINB3	SERPINB3 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 3	3699	0.039	0.4662	No
65	UBL3	UBL3 Entrez, Source	ubiquitin-like 3	3727	0.038	0.4662	No
66	NFKB1	NFKB1 Entrez, Source	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105)	3740	0.038	0.4673	No
67	IL6	IL6 Entrez, Source	interleukin 6 (interferon, beta 2)	3854	0.036	0.4606	No
68	RBMS1	RBMS1 Entrez, Source	RNA binding motif, single stranded interacting protein 1	4322	0.027	0.4266	No
69	RELA	RELA Entrez, Source	v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)	4483	0.024	0.4158	No
70	IL4R	IL4R Entrez, Source	interleukin 4 receptor	4494	0.024	0.4162	No
71	STK17B	STK17B Entrez, Source	serine/threonine kinase 17b (apoptosis-inducing)	4570	0.022	0.4117	No
72	VDR	VDR Entrez, Source	vitamin D (1,25- dihydroxyvitamin D3) receptor	4613	0.021	0.4097	No
73	KCNK3	KCNK3 Entrez, Source	potassium channel, subfamily K, member 3	4699	0.020	0.4043	No
74	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	4762	0.019	0.4006	No
75	CREM	CREM Entrez, Source	cAMP responsive element modulator	4794	0.019	0.3992	No
76	XCL1	XCL1 Entrez, Source	chemokine (C motif) ligand 1	4929	0.016	0.3899	No
77	INHBA	INHBA Entrez, Source	inhibin, beta A (activin A, activin AB alpha polypeptide)	5081	0.014	0.3792	No
78	FGL2	FGL2 Entrez, Source	fibrinogen-like 2	5086	0.014	0.3796	No
79	GATA3	GATA3 Entrez, Source	GATA binding protein 3	5124	0.013	0.3775	No
80	IL10RA	IL10RA Entrez, Source	interleukin 10 receptor, alpha	5276	0.011	0.3666	No
81	CTSL	CTSL Entrez, Source	cathepsin L	5451	0.008	0.3538	No
82	NKG7	NKG7 Entrez, Source	natural killer cell group 7 sequence	5655	0.005	0.3387	No
83	MAOA	MAOA Entrez, Source	monoamine oxidase A	5751	0.003	0.3317	No
84	CXCR4	CXCR4 Entrez, Source	chemokine (C-X-C motif) receptor 4	5981	0.000	0.3144	No
85	CDC25A	CDC25A Entrez, Source	cell division cycle 25A	6002	0.000	0.3129	No
86	CCL22	CCL22 Entrez, Source	chemokine (C-C motif) ligand 22	6089	-0.001	0.3064	No
87	RASA2	RASA2 Entrez, Source	RAS p21 protein activator 2	6217	-0.003	0.2970	No
88	CD86	CD86 Entrez, Source	CD86 molecule	6302	-0.005	0.2909	No
89	BCL2	BCL2 Entrez, Source	B-cell CLL/lymphoma 2	6363	-0.006	0.2867	No
90	GZMB	GZMB Entrez, Source	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	6537	-0.008	0.2740	No
91	IGHE	IGHE Entrez, Source	immunoglobulin heavy constant epsilon	6573	-0.009	0.2718	No
92	NFIL3	NFIL3 Entrez, Source	nuclear factor, interleukin 3 regulated	6595	-0.009	0.2707	No
93	HSPA8	HSPA8 Entrez, Source	heat shock 70kDa protein 8	6613	-0.009	0.2699	No
94	ID3	ID3 Entrez, Source	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	6682	-0.010	0.2653	No
95	TFEC	TFEC Entrez, Source	transcription factor EC	6760	-0.012	0.2600	No
96	ALDH1A2	ALDH1A2 Entrez, Source	aldehyde dehydrogenase 1 family, member A2	7402	-0.021	0.2126	No
97	GATA6	GATA6 Entrez, Source	GATA binding protein 6	7526	-0.023	0.2045	No
98	BCL2L11	BCL2L11 Entrez, Source	BCL2-like 11 (apoptosis facilitator)	7593	-0.024	0.2008	No
99	CHST10	CHST10 Entrez, Source	carbohydrate sulfotransferase 10	7723	-0.026	0.1924	No
100	SOCS3	SOCS3 Entrez, Source	suppressor of cytokine signaling 3	7799	-0.027	0.1881	No
101	IGF1	IGF1 Entrez, Source	insulin-like growth factor 1 (somatomedin C)	7950	-0.030	0.1784	No
102	IL13	IL13 Entrez, Source	interleukin 13	7984	-0.031	0.1775	No
103	CYP1B1	CYP1B1 Entrez, Source	cytochrome P450, family 1, subfamily B, polypeptide 1	7989	-0.031	0.1788	No
104	SLC11A2	SLC11A2 Entrez, Source	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	8634	-0.041	0.1322	No
105	ALOX15	ALOX15 Entrez, Source	arachidonate 15-lipoxygenase	8665	-0.041	0.1321	No
106	PMCH	PMCH Entrez, Source	pro-melanin-concentrating hormone	8741	-0.043	0.1286	No
107	CTSC	CTSC Entrez, Source	cathepsin C	9429	-0.055	0.0795	No
108	CSPG2	CSPG2 Entrez, Source	chondroitin sulfate proteoglycan 2 (versican)	9690	-0.060	0.0629	No
109	AHR	AHR Entrez, Source	aryl hydrocarbon receptor	9715	-0.060	0.0643	No
110	S100A9	S100A9 Entrez, Source	S100 calcium binding protein A9	9785	-0.062	0.0623	No
111	POU4F1	POU4F1 Entrez, Source	POU domain, class 4, transcription factor 1	10099	-0.068	0.0422	No
112	RASGRP1	RASGRP1 Entrez, Source	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	10196	-0.070	0.0386	No
113	HSPB8	HSPB8 Entrez, Source	heat shock 22kDa protein 8	10232	-0.071	0.0397	No
114	RDX	RDX Entrez, Source	radixin	10377	-0.074	0.0327	No
115	IL1RN	IL1RN Entrez, Source	interleukin 1 receptor antagonist	10398	-0.075	0.0351	No
116	SELE	SELE Entrez, Source	selectin E (endothelial adhesion molecule 1)	10446	-0.076	0.0355	No
117	LIFR	LIFR Entrez, Source	leukemia inhibitory factor receptor alpha	10469	-0.077	0.0379	No
118	LRRN3	LRRN3 Entrez, Source	leucine rich repeat neuronal 3	10493	-0.078	0.0402	No
119	MYC	MYC Entrez, Source	v-myc myelocytomatosis viral oncogene homolog (avian)	10547	-0.079	0.0404	No
120	EDNRA	EDNRA Entrez, Source	endothelin receptor type A	10650	-0.081	0.0369	No
121	GJA5	GJA5 Entrez, Source	gap junction protein, alpha 5, 40kDa (connexin 40)	10784	-0.085	0.0313	No
122	TOP2A	TOP2A Entrez, Source	topoisomerase (DNA) II alpha 170kDa	11066	-0.092	0.0148	No
123	EEF1A2	EEF1A2 Entrez, Source	eukaryotic translation elongation factor 1 alpha 2	11251	-0.097	0.0060	No
124	ENPP1	ENPP1 Entrez, Source	ectonucleotide pyrophosphatase/phosphodiesterase 1	11335	-0.100	0.0050	No
125	IL13RA1	IL13RA1 Entrez, Source	interleukin 13 receptor, alpha 1	11405	-0.102	0.0051	No
126	GNAI1	GNAI1 Entrez, Source	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	11660	-0.111	-0.0083	No
127	CH25H	CH25H Entrez, Source	cholesterol 25-hydroxylase	12142	-0.133	-0.0377	No
128	RIPK2	RIPK2 Entrez, Source	receptor-interacting serine-threonine kinase 2	12163	-0.135	-0.0321	No
129	DMD	DMD Entrez, Source	dystrophin (muscular dystrophy, Duchenne and Becker types)	12470	-0.153	-0.0473	No
130	MET	MET Entrez, Source	met proto-oncogene (hepatocyte growth factor receptor)	12611	-0.164	-0.0493	No
131	DNAJC3	DNAJC3 Entrez, Source	DnaJ (Hsp40) homolog, subfamily C, member 3	12958	-0.211	-0.0644	No
132	CASP2	CASP2 Entrez, Source	caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)	12967	-0.213	-0.0539	No
133	CA2	CA2 Entrez, Source	carbonic anhydrase II	12972	-0.213	-0.0430	No
134	MCM7	MCM7 Entrez, Source	MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)	13021	-0.223	-0.0349	No
135	MCM6	MCM6 Entrez, Source	MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)	13204	-0.304	-0.0328	No
136	EDG1	EDG1 Entrez, Source	endothelial differentiation, sphingolipid G-protein-coupled receptor, 1	13334	-0.822	0.0006	No