Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NI2_MOUSE_UP |
| Enrichment Score (ES) | 0.62231565 |
| Normalized Enrichment Score (NES) | 1.8751918 |
| Nominal p-value | 0.0054644807 |
| FDR q-value | 0.015749762 |
| FWER p-Value | 0.737 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 21 | 0.785 | 0.2079 | Yes |
| 2 | LOX | LOX Entrez, Source | lysyl oxidase | 154 | 0.441 | 0.3156 | Yes |
| 3 | ANGPTL4 | ANGPTL4 Entrez, Source | angiopoietin-like 4 | 493 | 0.230 | 0.3515 | Yes |
| 4 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 600 | 0.206 | 0.3986 | Yes |
| 5 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 754 | 0.176 | 0.4341 | Yes |
| 6 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 880 | 0.159 | 0.4671 | Yes |
| 7 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 960 | 0.151 | 0.5013 | Yes |
| 8 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 1043 | 0.142 | 0.5330 | Yes |
| 9 | ZFP36 | ZFP36 Entrez, Source | zinc finger protein 36, C3H type, homolog (mouse) | 1260 | 0.123 | 0.5496 | Yes |
| 10 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 1261 | 0.123 | 0.5823 | Yes |
| 11 | KLF6 | KLF6 Entrez, Source | Kruppel-like factor 6 | 1286 | 0.121 | 0.6128 | Yes |
| 12 | SPP1 | SPP1 Entrez, Source | secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) | 1776 | 0.094 | 0.6011 | Yes |
| 13 | SPHK1 | SPHK1 Entrez, Source | sphingosine kinase 1 | 1821 | 0.092 | 0.6223 | Yes |
| 14 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 2826 | 0.059 | 0.5627 | No |
| 15 | MAL | MAL Entrez, Source | mal, T-cell differentiation protein | 3112 | 0.052 | 0.5551 | No |
| 16 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | 0.5370 | No |
| 17 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 4283 | 0.028 | 0.4861 | No |
| 18 | MCL1 | MCL1 Entrez, Source | myeloid cell leukemia sequence 1 (BCL2-related) | 4349 | 0.026 | 0.4882 | No |
| 19 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 4386 | 0.026 | 0.4924 | No |
| 20 | CSTB | CSTB Entrez, Source | cystatin B (stefin B) | 4447 | 0.024 | 0.4944 | No |
| 21 | LCN2 | LCN2 Entrez, Source | lipocalin 2 (oncogene 24p3) | 5175 | 0.012 | 0.4430 | No |
| 22 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 5439 | 0.008 | 0.4254 | No |
| 23 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 6358 | -0.006 | 0.3579 | No |
| 24 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 6527 | -0.008 | 0.3475 | No |
| 25 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 7114 | -0.017 | 0.3080 | No |
| 26 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 9515 | -0.056 | 0.1427 | No |
| 27 | LRG1 | LRG1 Entrez, Source | leucine-rich alpha-2-glycoprotein 1 | 10489 | -0.077 | 0.0903 | No |
| 28 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | 0.1070 | No |
| 29 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 12775 | -0.181 | -0.0120 | No |
| 30 | RBM3 | RBM3 Entrez, Source | RNA binding motif (RNP1, RRM) protein 3 | 12930 | -0.204 | 0.0309 | No |
