Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NITROGEN_COMPOUND_CATABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6501724 |
| Normalized Enrichment Score (NES) | 1.797281 |
| Nominal p-value | 0.009596929 |
| FDR q-value | 0.026045984 |
| FWER p-Value | 0.973 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 144 | 0.453 | 0.1370 | Yes |
| 2 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 146 | 0.449 | 0.2833 | Yes |
| 3 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 272 | 0.326 | 0.3802 | Yes |
| 4 | DDAH1 | DDAH1 Entrez, Source | dimethylarginine dimethylaminohydrolase 1 | 421 | 0.254 | 0.4519 | Yes |
| 5 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 501 | 0.227 | 0.5202 | Yes |
| 6 | ARG1 | ARG1 Entrez, Source | arginase, liver | 704 | 0.185 | 0.5654 | Yes |
| 7 | COLQ | COLQ Entrez, Source | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 888 | 0.157 | 0.6030 | Yes |
| 8 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 1252 | 0.124 | 0.6160 | Yes |
| 9 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 1315 | 0.119 | 0.6502 | Yes |
| 10 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1962 | 0.087 | 0.6299 | No |
| 11 | MCCC2 | MCCC2 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 2111 | 0.080 | 0.6451 | No |
| 12 | ASL | ASL Entrez, Source | argininosuccinate lyase | 3041 | 0.053 | 0.5927 | No |
| 13 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 3681 | 0.039 | 0.5575 | No |
| 14 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 3853 | 0.036 | 0.5563 | No |
| 15 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 4885 | 0.017 | 0.4845 | No |
| 16 | MPST | MPST Entrez, Source | mercaptopyruvate sulfurtransferase | 5279 | 0.010 | 0.4584 | No |
| 17 | AMT | AMT Entrez, Source | aminomethyltransferase | 5396 | 0.009 | 0.4525 | No |
| 18 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 6406 | -0.006 | 0.3788 | No |
| 19 | DHPS | DHPS Entrez, Source | deoxyhypusine synthase | 8259 | -0.035 | 0.2512 | No |
| 20 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 8497 | -0.039 | 0.2461 | No |
| 21 | ASRGL1 | ASRGL1 Entrez, Source | asparaginase like 1 | 8649 | -0.041 | 0.2482 | No |
| 22 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8856 | -0.045 | 0.2474 | No |
| 23 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 10520 | -0.078 | 0.1481 | No |
| 24 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 11228 | -0.096 | 0.1265 | No |
| 25 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 11300 | -0.099 | 0.1533 | No |
