Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | NUCLEAR_ENVELOPE |
| Enrichment Score (ES) | -0.4527988 |
| Normalized Enrichment Score (NES) | -1.5458177 |
| Nominal p-value | 0.015151516 |
| FDR q-value | 0.18378651 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 730 | 0.181 | -0.0135 | No |
| 2 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 921 | 0.154 | 0.0074 | No |
| 3 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 1023 | 0.145 | 0.0330 | No |
| 4 | NUP50 | NUP50 Entrez, Source | nucleoporin 50kDa | 1297 | 0.120 | 0.0399 | No |
| 5 | PRICKLE1 | PRICKLE1 Entrez, Source | prickle homolog 1 (Drosophila) | 1377 | 0.115 | 0.0603 | No |
| 6 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 2391 | 0.071 | 0.0004 | No |
| 7 | SP140 | SP140 Entrez, Source | SP140 nuclear body protein | 3655 | 0.040 | -0.0855 | No |
| 8 | DDX19B | DDX19B Entrez, Source | DEAD (Asp-Glu-Ala-As) box polypeptide 19B | 4279 | 0.028 | -0.1260 | No |
| 9 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 4380 | 0.026 | -0.1276 | No |
| 10 | DULLARD | DULLARD Entrez, Source | dullard homolog (Xenopus laevis) | 4458 | 0.024 | -0.1279 | No |
| 11 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.1759 | No |
| 12 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 5231 | 0.011 | -0.1804 | No |
| 13 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 5810 | 0.003 | -0.2233 | No |
| 14 | GUCY2D | GUCY2D Entrez, Source | guanylate cyclase 2D, membrane (retina-specific) | 6125 | -0.002 | -0.2464 | No |
| 15 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6363 | -0.006 | -0.2630 | No |
| 16 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6561 | -0.008 | -0.2758 | No |
| 17 | NRM | NRM Entrez, Source | nurim (nuclear envelope membrane protein) | 6753 | -0.011 | -0.2876 | No |
| 18 | EMD | EMD Entrez, Source | emerin (Emery-Dreifuss muscular dystrophy) | 7369 | -0.021 | -0.3291 | No |
| 19 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 7528 | -0.023 | -0.3358 | No |
| 20 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.3683 | No |
| 21 | GRINL1A | GRINL1A Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A | 9169 | -0.050 | -0.4403 | Yes |
| 22 | TMPO | TMPO Entrez, Source | thymopoietin | 9189 | -0.050 | -0.4302 | Yes |
| 23 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 9275 | -0.052 | -0.4246 | Yes |
| 24 | SREBF1 | SREBF1 Entrez, Source | sterol regulatory element binding transcription factor 1 | 9603 | -0.058 | -0.4360 | Yes |
| 25 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 9660 | -0.059 | -0.4267 | Yes |
| 26 | SENP2 | SENP2 Entrez, Source | SUMO1/sentrin/SMT3 specific peptidase 2 | 10008 | -0.066 | -0.4376 | Yes |
| 27 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 10200 | -0.071 | -0.4358 | Yes |
| 28 | KPNA1 | KPNA1 Entrez, Source | karyopherin alpha 1 (importin alpha 5) | 10204 | -0.071 | -0.4198 | Yes |
| 29 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10603 | -0.080 | -0.4315 | Yes |
| 30 | KPNA3 | KPNA3 Entrez, Source | karyopherin alpha 3 (importin alpha 4) | 10744 | -0.084 | -0.4228 | Yes |
| 31 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 10866 | -0.087 | -0.4119 | Yes |
| 32 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 11141 | -0.094 | -0.4109 | Yes |
| 33 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 11294 | -0.098 | -0.3998 | Yes |
| 34 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11330 | -0.100 | -0.3796 | Yes |
| 35 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11338 | -0.100 | -0.3572 | Yes |
| 36 | GUCY2F | GUCY2F Entrez, Source | guanylate cyclase 2F, retinal | 11499 | -0.106 | -0.3450 | Yes |
| 37 | BNIP1 | BNIP1 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 1 | 11896 | -0.121 | -0.3470 | Yes |
| 38 | MATR3 | MATR3 Entrez, Source | matrin 3 | 11949 | -0.124 | -0.3225 | Yes |
| 39 | XPO7 | XPO7 Entrez, Source | exportin 7 | 12002 | -0.127 | -0.2974 | Yes |
| 40 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 12073 | -0.130 | -0.2728 | Yes |
| 41 | NUP88 | NUP88 Entrez, Source | nucleoporin 88kDa | 12191 | -0.136 | -0.2504 | Yes |
| 42 | LBR | LBR Entrez, Source | lamin B receptor | 12381 | -0.148 | -0.2309 | Yes |
| 43 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 12429 | -0.150 | -0.2000 | Yes |
| 44 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.1657 | Yes |
| 45 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 12441 | -0.151 | -0.1319 | Yes |
| 46 | SNUPN | SNUPN Entrez, Source | snurportin 1 | 12833 | -0.189 | -0.1180 | Yes |
| 47 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 12994 | -0.216 | -0.0804 | Yes |
| 48 | NUP54 | NUP54 Entrez, Source | nucleoporin 54kDa | 13023 | -0.224 | -0.0313 | Yes |
| 49 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 13073 | -0.241 | 0.0202 | Yes |
