Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetNUCLEAR_LUMEN
Enrichment Score (ES)-0.43422955
Normalized Enrichment Score (NES)-1.8142247
Nominal p-value0.0
FDR q-value0.04354183
FWER p-Value0.866
Table: GSEA Results Summary



Fig 1: Enrichment plot: NUCLEAR_LUMEN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1NOL3NOL3
Entrez,  Source
nucleolar protein 3 (apoptosis repressor with CARD domain)2020.3850.0136No
2LMO4LMO4
Entrez,  Source
LIM domain only 48080.169-0.0196No
3DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 98860.157-0.0136No
4PPARGC1APPARGC1A
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, alpha11810.130-0.0262No
5MEN1MEN1
Entrez,  Source
multiple endocrine neoplasia I11940.128-0.0174No
6EPAS1EPAS1
Entrez,  Source
endothelial PAS domain protein 113210.118-0.0181No
7KLHL7KLHL7
Entrez,  Source
kelch-like 7 (Drosophila)15810.103-0.0300No
8CIB1CIB1
Entrez,  Source
calcium and integrin binding 1 (calmyrin)16880.098-0.0307No
9NAP1L2NAP1L2
Entrez,  Source
nucleosome assembly protein 1-like 217110.097-0.0250No
10HDAC7AHDAC7A
Entrez,  Source
histone deacetylase 7A19590.087-0.0373No
11DEDDDEDD
Entrez,  Source
death effector domain containing20430.083-0.0373No
12SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 223000.074-0.0511No
13BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 323910.071-0.0526No
14PPP1R9BPPP1R9B
Entrez,  Source
protein phosphatase 1, regulatory subunit 9B, spinophilin29000.057-0.0869No
15NCR1NCR1
Entrez,  Source
natural cytotoxicity triggering receptor 129940.055-0.0898No
16GTF3C2GTF3C2
Entrez,  Source
general transcription factor IIIC, polypeptide 2, beta 110kDa31710.050-0.0994No
17ATXN1ATXN1
Entrez,  Source
ataxin 131970.050-0.0976No
18ELL2ELL2
Entrez,  Source
elongation factor, RNA polymerase II, 233520.046-0.1058No
19CDKN2ACDKN2A
Entrez,  Source
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)34010.045-0.1060No
20NCOA6NCOA6
Entrez,  Source
nuclear receptor coactivator 635270.042-0.1123No
21SMARCD2SMARCD2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 235660.041-0.1121No
22EXOSC9EXOSC9
Entrez,  Source
exosome component 936100.041-0.1123No
23SP140SP140
Entrez,  Source
SP140 nuclear body protein36550.040-0.1127No
24ISG20ISG20
Entrez,  Source
interferon stimulated exonuclease gene 20kDa37320.038-0.1156No
25HDAC5HDAC5
Entrez,  Source
histone deacetylase 537420.038-0.1134No
26TAF9TAF9
Entrez,  Source
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa37570.037-0.1116No
27REXO4REXO4
Entrez,  Source
REX4, RNA exonuclease 4 homolog (S. cerevisiae)39890.033-0.1267No
28HCLS1HCLS1
Entrez,  Source
hematopoietic cell-specific Lyn substrate 140750.031-0.1308No
29MCRS1MCRS1
Entrez,  Source
microspherule protein 143090.027-0.1464No
30NARFNARF
Entrez,  Source
nuclear prelamin A recognition factor43800.026-0.1498No
31SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 444320.025-0.1518No
32RELARELA
Entrez,  Source
v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian)44830.024-0.1538No
33CDK9CDK9
Entrez,  Source
cyclin-dependent kinase 9 (CDC2-related kinase)45580.022-0.1577No
34NFYANFYA
Entrez,  Source
nuclear transcription factor Y, alpha48330.018-0.1772No
35PTF1APTF1A
Entrez,  Source
pancreas specific transcription factor, 1a48860.017-0.1798No
36HDAC3HDAC3
Entrez,  Source
histone deacetylase 349670.016-0.1847No
37ACTBACTB
Entrez,  Source
actin, beta50410.014-0.1892No
38ZBTB16ZBTB16
Entrez,  Source
zinc finger and BTB domain containing 1650420.014-0.1881No
39NFYBNFYB
Entrez,  Source
nuclear transcription factor Y, beta50580.014-0.1882No
40PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 152310.011-0.2004No
41HTATIPHTATIP
Entrez,  Source
HIV-1 Tat interacting protein, 60kDa55280.007-0.2223No
42ASNA1ASNA1
Entrez,  Source
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)58710.002-0.2481No
43ZNF148ZNF148
Entrez,  Source
zinc finger protein 14859160.001-0.2513No
44TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I6078-0.001-0.2635No
45TBPTBP
Entrez,  Source
TATA box binding protein6398-0.006-0.2872No
46SMARCB1SMARCB1
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 16408-0.006-0.2874No
47SMARCA4SMARCA4
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 46475-0.007-0.2919No
48CHAF1BCHAF1B
Entrez,  Source
chromatin assembly factor 1, subunit B (p60)6494-0.008-0.2927No
49NUP98NUP98
Entrez,  Source
nucleoporin 98kDa6561-0.008-0.2970No
50PNMA1PNMA1
Entrez,  Source
paraneoplastic antigen MA16758-0.012-0.3110No
51COILCOIL
Entrez,  Source
coilin6923-0.014-0.3224No
52PRM2PRM2
Entrez,  Source
protamine 27003-0.015-0.3273No
53NAP1L4NAP1L4
Entrez,  Source
nucleosome assembly protein 1-like 47012-0.015-0.3267No
54ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)7085-0.016-0.3310No
55SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)7113-0.017-0.3317No
56NFYCNFYC
Entrez,  Source
nuclear transcription factor Y, gamma7410-0.021-0.3526No
57GATAD2AGATAD2A
Entrez,  Source
GATA zinc finger domain containing 2A7565-0.024-0.3625No
58GIT2GIT2
Entrez,  Source
G protein-coupled receptor kinase interactor 27717-0.026-0.3720No
59TAF6TAF6
Entrez,  Source
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa7744-0.027-0.3720No
60HIF1AHIF1A
Entrez,  Source
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7751-0.027-0.3704No
61KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)7811-0.028-0.3728No
62SUB1SUB1
Entrez,  Source
SUB1 homolog (S. cerevisiae)7882-0.029-0.3760No
63PPARGC1BPPARGC1B
Entrez,  Source
peroxisome proliferative activated receptor, gamma, coactivator 1, beta7905-0.029-0.3755No
64IKBKAPIKBKAP
Entrez,  Source
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein7916-0.029-0.3740No
65SMARCD3SMARCD3
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 37948-0.030-0.3741No
66RTCD1RTCD1
Entrez,  Source
RNA terminal phosphate cyclase domain 18083-0.032-0.3819No
67PHF12PHF12
Entrez,  Source
PHD finger protein 128193-0.034-0.3876No
68TEP1TEP1
Entrez,  Source
telomerase-associated protein 18212-0.034-0.3864No
69HDAC10HDAC10
Entrez,  Source
histone deacetylase 108278-0.035-0.3887No
70PITX2PITX2
Entrez,  Source
paired-like homeodomain transcription factor 28349-0.037-0.3912No
71CPSF3CPSF3
Entrez,  Source
cleavage and polyadenylation specific factor 3, 73kDa8375-0.037-0.3903No
72SMAD2SMAD2
Entrez,  Source
SMAD, mothers against DPP homolog 2 (Drosophila)8430-0.038-0.3916No
73SC65SC65
Entrez,  Source
-8463-0.038-0.3911No
74NUDT21NUDT21
Entrez,  Source
nudix (nucleoside diphosphate linked moiety X)-type motif 218466-0.038-0.3884No
75OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase8478-0.039-0.3863No
76THRAP3THRAP3
Entrez,  Source
thyroid hormone receptor associated protein 38530-0.039-0.3873No
77TAF11TAF11
Entrez,  Source
TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa8562-0.040-0.3866No
78FOXE3FOXE3
Entrez,  Source
forkhead box E38571-0.040-0.3842No
79SAP18SAP18
Entrez,  Source
Sin3A-associated protein, 18kDa8573-0.040-0.3813No
80DDX24DDX24
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 248687-0.042-0.3867No
81UBE2IUBE2I
Entrez,  Source
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)8725-0.043-0.3863No
82CHEK2CHEK2
Entrez,  Source
CHK2 checkpoint homolog (S. pombe)8735-0.043-0.3838No
83INTS6INTS6
Entrez,  Source
integrator complex subunit 68753-0.043-0.3818No
84DDX47DDX47
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 478805-0.044-0.3824No
85SLU7SLU7
Entrez,  Source
-8831-0.044-0.3810No
86RB1RB1
Entrez,  Source
retinoblastoma 1 (including osteosarcoma)9017-0.048-0.3914No
87MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 29092-0.049-0.3934No
88HDAC6HDAC6
Entrez,  Source
histone deacetylase 69263-0.052-0.4024No
89NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)9310-0.053-0.4019No
90PAX8PAX8
Entrez,  Source
paired box gene 89509-0.056-0.4127No
91PHBPHB
Entrez,  Source
prohibitin9567-0.057-0.4128No
92GCM1GCM1
Entrez,  Source
glial cells missing homolog 1 (Drosophila)9613-0.058-0.4118No
93RPL3RPL3
Entrez,  Source
ribosomal protein L39736-0.061-0.4165No
94XRCC6XRCC6
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)9780-0.062-0.4151No
95GEMIN6GEMIN6
Entrez,  Source
gem (nuclear organelle) associated protein 69841-0.063-0.4149No
96NKX2-5NKX2-5
Entrez,  Source
NK2 transcription factor related, locus 5 (Drosophila)9922-0.065-0.4161No
97FGF18FGF18
Entrez,  Source
fibroblast growth factor 189933-0.065-0.4120No
98HMGA1HMGA1
Entrez,  Source
high mobility group AT-hook 19950-0.065-0.4083No
99SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 310069-0.068-0.4122No
100PTBP1PTBP1
Entrez,  Source
polypyrimidine tract binding protein 110104-0.068-0.4096No
101SYMPKSYMPK
Entrez,  Source
symplekin10270-0.072-0.4167No
102NAP1L1NAP1L1
Entrez,  Source
nucleosome assembly protein 1-like 110281-0.072-0.4121No
103MPGMPG
Entrez,  Source
N-methylpurine-DNA glycosylase10506-0.078-0.4232No
104HES6HES6
Entrez,  Source
hairy and enhancer of split 6 (Drosophila)10589-0.080-0.4234No
105SFRS2SFRS2
Entrez,  Source
splicing factor, arginine/serine-rich 210691-0.082-0.4249No
106HNRPKHNRPK
Entrez,  Source
heterogeneous nuclear ribonucleoprotein K10815-0.086-0.4278Yes
107CLOCKCLOCK
Entrez,  Source
clock homolog (mouse)10868-0.087-0.4252Yes
108GTF2F1GTF2F1
Entrez,  Source
general transcription factor IIF, polypeptide 1, 74kDa10980-0.090-0.4268Yes
109TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa11066-0.092-0.4264Yes
110TFIP11TFIP11
Entrez,  Source
tuftelin interacting protein 1111088-0.093-0.4210Yes
111RPL11RPL11
Entrez,  Source
ribosomal protein L1111095-0.093-0.4144Yes
112IMP4IMP4
Entrez,  Source
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)11124-0.094-0.4095Yes
113LYARLYAR
Entrez,  Source
-11179-0.095-0.4064Yes
114GTF3C1GTF3C1
Entrez,  Source
general transcription factor IIIC, polypeptide 1, alpha 220kDa11181-0.095-0.3994Yes
115HDAC2HDAC2
Entrez,  Source
histone deacetylase 211182-0.095-0.3922Yes
116RBM39RBM39
Entrez,  Source
RNA binding motif protein 3911211-0.096-0.3871Yes
117DKC1DKC1
Entrez,  Source
dyskeratosis congenita 1, dyskerin11229-0.096-0.3811Yes
118ARID1BARID1B
Entrez,  Source
AT rich interactive domain 1B (SWI1-like)11241-0.097-0.3747Yes
119TP53TP53
Entrez,  Source
tumor protein p53 (Li-Fraumeni syndrome)11337-0.100-0.3744Yes
120MED4MED4
Entrez,  Source
mediator of RNA polymerase II transcription, subunit 4 homolog (S. cerevisiae)11379-0.101-0.3699Yes
121RPL35RPL35
Entrez,  Source
ribosomal protein L3511505-0.106-0.3714Yes
122GNL3GNL3
Entrez,  Source
guanine nucleotide binding protein-like 3 (nucleolar)11580-0.109-0.3689Yes
123ATXN3ATXN3
Entrez,  Source
ataxin 311788-0.116-0.3758Yes
124ACTL6AACTL6A
Entrez,  Source
actin-like 6A11816-0.118-0.3690Yes
125FMR1FMR1
Entrez,  Source
fragile X mental retardation 111863-0.120-0.3635Yes
126RPP40RPP40
Entrez,  Source
ribonuclease P 40kDa subunit11919-0.122-0.3585Yes
127NAP1L3NAP1L3
Entrez,  Source
nucleosome assembly protein 1-like 311966-0.125-0.3526Yes
128TAF2TAF2
Entrez,  Source
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa12029-0.128-0.3477Yes
129DNMT3ADNMT3A
Entrez,  Source
DNA (cytosine-5-)-methyltransferase 3 alpha12031-0.128-0.3382Yes
130POLR3CPOLR3C
Entrez,  Source
polymerase (RNA) III (DNA directed) polypeptide C (62kD)12038-0.128-0.3290Yes
131GTF2H4GTF2H4
Entrez,  Source
general transcription factor IIH, polypeptide 4, 52kDa12050-0.129-0.3201Yes
132RPP38RPP38
Entrez,  Source
ribonuclease P/MRP 38kDa subunit12108-0.132-0.3145Yes
133RPS19RPS19
Entrez,  Source
ribosomal protein S1912113-0.132-0.3049Yes
134NOC4LNOC4L
Entrez,  Source
nucleolar complex associated 4 homolog (S. cerevisiae)12118-0.133-0.2952Yes
135MKI67IPMKI67IP
Entrez,  Source
MKI67 (FHA domain) interacting nucleolar phosphoprotein12289-0.142-0.2975Yes
136NUFIP1NUFIP1
Entrez,  Source
nuclear fragile X mental retardation protein interacting protein 112295-0.142-0.2872Yes
137RUVBL2RUVBL2
Entrez,  Source
RuvB-like 2 (E. coli)12316-0.144-0.2779Yes
138MYBBP1AMYBBP1A
Entrez,  Source
MYB binding protein (P160) 1a12333-0.144-0.2682Yes
139DDX56DDX56
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5612337-0.145-0.2576Yes
140UBTFUBTF
Entrez,  Source
upstream binding transcription factor, RNA polymerase I12345-0.145-0.2472Yes
141NCBP1NCBP1
Entrez,  Source
nuclear cap binding protein subunit 1, 80kDa12406-0.149-0.2406Yes
142CIRH1ACIRH1A
Entrez,  Source
cirrhosis, autosomal recessive 1A (cirhin)12459-0.152-0.2331Yes
143NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)12500-0.155-0.2245Yes
144NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)12505-0.155-0.2132Yes
145PPIGPPIG
Entrez,  Source
peptidylprolyl isomerase G (cyclophilin G)12641-0.167-0.2108Yes
146NUAK2NUAK2
Entrez,  Source
NUAK family, SNF1-like kinase, 212649-0.168-0.1987Yes
147DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12773-0.181-0.1945Yes
148TDGTDG
Entrez,  Source
thymine-DNA glycosylase12893-0.199-0.1886Yes
149SLC29A2SLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 212900-0.200-0.1740Yes
150FUSIP1FUSIP1
Entrez,  Source
FUS interacting protein (serine/arginine-rich) 112913-0.201-0.1598Yes
151NCLNCL
Entrez,  Source
nucleolin12916-0.202-0.1447Yes
152XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)12994-0.216-0.1343Yes
153RUVBL1RUVBL1
Entrez,  Source
RuvB-like 1 (E. coli)12996-0.217-0.1181Yes
154NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 113015-0.221-0.1028Yes
155MCM7MCM7
Entrez,  Source
MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)13021-0.223-0.0864Yes
156NUP54NUP54
Entrez,  Source
nucleoporin 54kDa13023-0.224-0.0697Yes
157APTXAPTX
Entrez,  Source
aprataxin13079-0.242-0.0556Yes
158ARNTLARNTL
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator-like13133-0.262-0.0400Yes
159MRE11AMRE11A
Entrez,  Source
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)13244-0.339-0.0229Yes
160SDAD1SDAD1
Entrez,  Source
SDA1 domain containing 113284-0.4020.0044Yes
Table: GSEA details [plain text format]



Fig 2: NUCLEAR_LUMEN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: NUCLEAR_LUMEN: Random ES distribution   
Gene set null distribution of ES for NUCLEAR_LUMEN