Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | NUCLEAR_MEMBRANE |
| Enrichment Score (ES) | -0.5107691 |
| Normalized Enrichment Score (NES) | -1.6371778 |
| Nominal p-value | 0.013363029 |
| FDR q-value | 0.11766101 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RETSAT | RETSAT Entrez, Source | retinol saturase (all-trans-retinol 13,14-reductase) | 730 | 0.181 | 0.0004 | No |
| 2 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 1023 | 0.145 | 0.0227 | No |
| 3 | NUP50 | NUP50 Entrez, Source | nucleoporin 50kDa | 1297 | 0.120 | 0.0389 | No |
| 4 | PRICKLE1 | PRICKLE1 Entrez, Source | prickle homolog 1 (Drosophila) | 1377 | 0.115 | 0.0681 | No |
| 5 | DDX19B | DDX19B Entrez, Source | DEAD (Asp-Glu-Ala-As) box polypeptide 19B | 4279 | 0.028 | -0.1414 | No |
| 6 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 4380 | 0.026 | -0.1410 | No |
| 7 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 5136 | 0.013 | -0.1939 | No |
| 8 | GUCY2D | GUCY2D Entrez, Source | guanylate cyclase 2D, membrane (retina-specific) | 6125 | -0.002 | -0.2675 | No |
| 9 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6363 | -0.006 | -0.2835 | No |
| 10 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 6561 | -0.008 | -0.2958 | No |
| 11 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 8059 | -0.032 | -0.3985 | No |
| 12 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 9275 | -0.052 | -0.4739 | No |
| 13 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 9660 | -0.059 | -0.4847 | No |
| 14 | SENP2 | SENP2 Entrez, Source | SUMO1/sentrin/SMT3 specific peptidase 2 | 10008 | -0.066 | -0.4904 | Yes |
| 15 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 10200 | -0.071 | -0.4832 | Yes |
| 16 | KPNA1 | KPNA1 Entrez, Source | karyopherin alpha 1 (importin alpha 5) | 10204 | -0.071 | -0.4619 | Yes |
| 17 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10603 | -0.080 | -0.4674 | Yes |
| 18 | KPNA3 | KPNA3 Entrez, Source | karyopherin alpha 3 (importin alpha 4) | 10744 | -0.084 | -0.4522 | Yes |
| 19 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 10866 | -0.087 | -0.4346 | Yes |
| 20 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 11141 | -0.094 | -0.4264 | Yes |
| 21 | EIF5A | EIF5A Entrez, Source | eukaryotic translation initiation factor 5A | 11294 | -0.098 | -0.4077 | Yes |
| 22 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11330 | -0.100 | -0.3799 | Yes |
| 23 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11338 | -0.100 | -0.3498 | Yes |
| 24 | GUCY2F | GUCY2F Entrez, Source | guanylate cyclase 2F, retinal | 11499 | -0.106 | -0.3295 | Yes |
| 25 | MATR3 | MATR3 Entrez, Source | matrin 3 | 11949 | -0.124 | -0.3253 | Yes |
| 26 | XPO7 | XPO7 Entrez, Source | exportin 7 | 12002 | -0.127 | -0.2905 | Yes |
| 27 | MRPL19 | MRPL19 Entrez, Source | mitochondrial ribosomal protein L19 | 12073 | -0.130 | -0.2559 | Yes |
| 28 | NUP88 | NUP88 Entrez, Source | nucleoporin 88kDa | 12191 | -0.136 | -0.2231 | Yes |
| 29 | LBR | LBR Entrez, Source | lamin B receptor | 12381 | -0.148 | -0.1922 | Yes |
| 30 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 12429 | -0.150 | -0.1499 | Yes |
| 31 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 12430 | -0.150 | -0.1040 | Yes |
| 32 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 12441 | -0.151 | -0.0587 | Yes |
| 33 | SNUPN | SNUPN Entrez, Source | snurportin 1 | 12833 | -0.189 | -0.0302 | Yes |
| 34 | NUP54 | NUP54 Entrez, Source | nucleoporin 54kDa | 13023 | -0.224 | 0.0240 | Yes |
