Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | NUCLEOLUS |
| Enrichment Score (ES) | -0.5740699 |
| Normalized Enrichment Score (NES) | -1.9454882 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.014619349 |
| FWER p-Value | 0.27 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 202 | 0.385 | 0.0587 | No |
| 2 | DNAJB9 | DNAJB9 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 9 | 886 | 0.157 | 0.0376 | No |
| 3 | KLHL7 | KLHL7 Entrez, Source | kelch-like 7 (Drosophila) | 1581 | 0.103 | 0.0052 | No |
| 4 | DEDD | DEDD Entrez, Source | death effector domain containing | 2043 | 0.083 | -0.0134 | No |
| 5 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 3401 | 0.045 | -0.1068 | No |
| 6 | EXOSC9 | EXOSC9 Entrez, Source | exosome component 9 | 3610 | 0.041 | -0.1147 | No |
| 7 | REXO4 | REXO4 Entrez, Source | REX4, RNA exonuclease 4 homolog (S. cerevisiae) | 3989 | 0.033 | -0.1368 | No |
| 8 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 5231 | 0.011 | -0.2279 | No |
| 9 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 5871 | 0.002 | -0.2756 | No |
| 10 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6078 | -0.001 | -0.2909 | No |
| 11 | PNMA1 | PNMA1 Entrez, Source | paraneoplastic antigen MA1 | 6758 | -0.012 | -0.3397 | No |
| 12 | COIL | COIL Entrez, Source | coilin | 6923 | -0.014 | -0.3494 | No |
| 13 | IKBKAP | IKBKAP Entrez, Source | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein | 7916 | -0.029 | -0.4184 | No |
| 14 | SC65 | SC65 Entrez, Source | - | 8463 | -0.038 | -0.4521 | No |
| 15 | DDX24 | DDX24 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 | 8687 | -0.042 | -0.4608 | No |
| 16 | DDX47 | DDX47 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 | 8805 | -0.044 | -0.4612 | No |
| 17 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 9092 | -0.049 | -0.4734 | No |
| 18 | NF2 | NF2 Entrez, Source | neurofibromin 2 (bilateral acoustic neuroma) | 9310 | -0.053 | -0.4795 | No |
| 19 | RPL3 | RPL3 Entrez, Source | ribosomal protein L3 | 9736 | -0.061 | -0.4999 | No |
| 20 | FGF18 | FGF18 Entrez, Source | fibroblast growth factor 18 | 9933 | -0.065 | -0.5021 | No |
| 21 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 10104 | -0.068 | -0.5018 | No |
| 22 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 11066 | -0.092 | -0.5564 | Yes |
| 23 | RPL11 | RPL11 Entrez, Source | ribosomal protein L11 | 11095 | -0.093 | -0.5406 | Yes |
| 24 | IMP4 | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 11124 | -0.094 | -0.5247 | Yes |
| 25 | LYAR | LYAR Entrez, Source | - | 11179 | -0.095 | -0.5105 | Yes |
| 26 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 11229 | -0.096 | -0.4957 | Yes |
| 27 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11337 | -0.100 | -0.4845 | Yes |
| 28 | RPL35 | RPL35 Entrez, Source | ribosomal protein L35 | 11505 | -0.106 | -0.4767 | Yes |
| 29 | GNL3 | GNL3 Entrez, Source | guanine nucleotide binding protein-like 3 (nucleolar) | 11580 | -0.109 | -0.4614 | Yes |
| 30 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 11863 | -0.120 | -0.4596 | Yes |
| 31 | RPP40 | RPP40 Entrez, Source | ribonuclease P 40kDa subunit | 11919 | -0.122 | -0.4403 | Yes |
| 32 | RPP38 | RPP38 Entrez, Source | ribonuclease P/MRP 38kDa subunit | 12108 | -0.132 | -0.4290 | Yes |
| 33 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 12113 | -0.132 | -0.4039 | Yes |
| 34 | NOC4L | NOC4L Entrez, Source | nucleolar complex associated 4 homolog (S. cerevisiae) | 12118 | -0.133 | -0.3788 | Yes |
| 35 | MKI67IP | MKI67IP Entrez, Source | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 12289 | -0.142 | -0.3643 | Yes |
| 36 | NUFIP1 | NUFIP1 Entrez, Source | nuclear fragile X mental retardation protein interacting protein 1 | 12295 | -0.142 | -0.3375 | Yes |
| 37 | MYBBP1A | MYBBP1A Entrez, Source | MYB binding protein (P160) 1a | 12333 | -0.144 | -0.3125 | Yes |
| 38 | DDX56 | DDX56 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 | 12337 | -0.145 | -0.2850 | Yes |
| 39 | UBTF | UBTF Entrez, Source | upstream binding transcription factor, RNA polymerase I | 12345 | -0.145 | -0.2576 | Yes |
| 40 | CIRH1A | CIRH1A Entrez, Source | cirrhosis, autosomal recessive 1A (cirhin) | 12459 | -0.152 | -0.2370 | Yes |
| 41 | NOL5A | NOL5A Entrez, Source | nucleolar protein 5A (56kDa with KKE/D repeat) | 12500 | -0.155 | -0.2103 | Yes |
| 42 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 12505 | -0.155 | -0.1809 | Yes |
| 43 | SLC29A2 | SLC29A2 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 2 | 12900 | -0.200 | -0.1722 | Yes |
| 44 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.1345 | Yes |
| 45 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 13015 | -0.221 | -0.0993 | Yes |
| 46 | APTX | APTX Entrez, Source | aprataxin | 13079 | -0.242 | -0.0576 | Yes |
| 47 | SDAD1 | SDAD1 Entrez, Source | SDA1 domain containing 1 | 13284 | -0.402 | 0.0044 | Yes |
