Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | P53_BRCA1_UP |
| Enrichment Score (ES) | -0.52338755 |
| Normalized Enrichment Score (NES) | -1.5738473 |
| Nominal p-value | 0.032327585 |
| FDR q-value | 0.15499623 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LPIN1 | LPIN1 Entrez, Source | lipin 1 | 149 | 0.447 | 0.1257 | No |
| 2 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 1049 | 0.141 | 0.1015 | No |
| 3 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 1942 | 0.087 | 0.0612 | No |
| 4 | CTSF | CTSF Entrez, Source | cathepsin F | 2228 | 0.076 | 0.0632 | No |
| 5 | CTSH | CTSH Entrez, Source | cathepsin H | 2723 | 0.062 | 0.0451 | No |
| 6 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | -0.0005 | No |
| 7 | COX6B2 | COX6B2 Entrez, Source | cytochrome c oxidase subunit VIb polypeptide 2 (testis) | 3636 | 0.040 | 0.0021 | No |
| 8 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 4179 | 0.030 | -0.0295 | No |
| 9 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 4543 | 0.022 | -0.0499 | No |
| 10 | PQLC3 | PQLC3 Entrez, Source | PQ loop repeat containing 3 | 4686 | 0.020 | -0.0544 | No |
| 11 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 4877 | 0.017 | -0.0634 | No |
| 12 | FXYD3 | FXYD3 Entrez, Source | FXYD domain containing ion transport regulator 3 | 6943 | -0.014 | -0.2141 | No |
| 13 | PTPRV | PTPRV Entrez, Source | protein tyrosine phosphatase, receptor type, V (pseudogene) | 7287 | -0.019 | -0.2339 | No |
| 14 | ZMAT3 | ZMAT3 Entrez, Source | zinc finger, matrin type 3 | 8994 | -0.047 | -0.3475 | No |
| 15 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11337 | -0.100 | -0.4928 | Yes |
| 16 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 11645 | -0.111 | -0.4818 | Yes |
| 17 | PHLDA3 | PHLDA3 Entrez, Source | pleckstrin homology-like domain, family A, member 3 | 11766 | -0.116 | -0.4554 | Yes |
| 18 | ROBO1 | ROBO1 Entrez, Source | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 12116 | -0.133 | -0.4410 | Yes |
| 19 | ENPP2 | ENPP2 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) | 12368 | -0.147 | -0.4148 | Yes |
| 20 | EPHX1 | EPHX1 Entrez, Source | epoxide hydrolase 1, microsomal (xenobiotic) | 12715 | -0.175 | -0.3872 | Yes |
| 21 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 12854 | -0.192 | -0.3386 | Yes |
| 22 | SRXN1 | SRXN1 Entrez, Source | sulfiredoxin 1 homolog (S. cerevisiae) | 13053 | -0.234 | -0.2817 | Yes |
| 23 | FAS | FAS Entrez, Source | Fas (TNF receptor superfamily, member 6) | 13164 | -0.277 | -0.2050 | Yes |
| 24 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 13196 | -0.299 | -0.1158 | Yes |
| 25 | APOBEC1 | APOBEC1 Entrez, Source | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 13290 | -0.414 | 0.0039 | Yes |
