Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PARP_KO_UP |
| Enrichment Score (ES) | 0.76963496 |
| Normalized Enrichment Score (NES) | 2.111707 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0010941501 |
| FWER p-Value | 0.025 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 10 | 0.885 | 0.1948 | Yes |
| 2 | TINAGL1 | TINAGL1 Entrez, Source | tubulointerstitial nephritis antigen-like 1 | 36 | 0.709 | 0.3495 | Yes |
| 3 | MGP | MGP Entrez, Source | matrix Gla protein | 52 | 0.634 | 0.4883 | Yes |
| 4 | FST | FST Entrez, Source | follistatin | 169 | 0.423 | 0.5731 | Yes |
| 5 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 199 | 0.391 | 0.6573 | Yes |
| 6 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 329 | 0.291 | 0.7118 | Yes |
| 7 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 365 | 0.274 | 0.7696 | Yes |
| 8 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 1170 | 0.131 | 0.7381 | No |
| 9 | NOV | NOV Entrez, Source | nephroblastoma overexpressed gene | 1227 | 0.126 | 0.7617 | No |
| 10 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 1890 | 0.089 | 0.7316 | No |
| 11 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 2356 | 0.072 | 0.7127 | No |
| 12 | DCN | DCN Entrez, Source | decorin | 3405 | 0.045 | 0.6439 | No |
| 13 | CTTN | CTTN Entrez, Source | cortactin | 3500 | 0.043 | 0.6463 | No |
| 14 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3506 | 0.043 | 0.6554 | No |
| 15 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 4156 | 0.030 | 0.6133 | No |
| 16 | ELN | ELN Entrez, Source | elastin (supravalvular aortic stenosis, Williams-Beuren syndrome) | 4386 | 0.026 | 0.6018 | No |
| 17 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 4543 | 0.022 | 0.5950 | No |
| 18 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 4877 | 0.017 | 0.5738 | No |
| 19 | B2M | B2M Entrez, Source | beta-2-microglobulin | 5795 | 0.003 | 0.5056 | No |
| 20 | CD81 | CD81 Entrez, Source | CD81 molecule | 6049 | -0.001 | 0.4867 | No |
| 21 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 7557 | -0.023 | 0.3788 | No |
| 22 | EEF2 | EEF2 Entrez, Source | eukaryotic translation elongation factor 2 | 7846 | -0.028 | 0.3633 | No |
| 23 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 9082 | -0.049 | 0.2813 | No |
| 24 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 10603 | -0.080 | 0.1848 | No |
| 25 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | 0.1660 | No |
