Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetPENG_GLUTAMINE_DN
Enrichment Score (ES)-0.47235242
Normalized Enrichment Score (NES)-2.0157437
Nominal p-value0.0
FDR q-value0.0075870575
FWER p-Value0.101
Table: GSEA Results Summary



Fig 1: Enrichment plot: PENG_GLUTAMINE_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LDHBLDHB
Entrez,  Source
lactate dehydrogenase B220.7850.0442No
2PFKPPFKP
Entrez,  Source
phosphofructokinase, platelet290.7530.0877No
3HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 43050.3030.0845No
4EMP3EMP3
Entrez,  Source
epithelial membrane protein 37550.1760.0607No
5TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)8210.1660.0654No
6CLIC1CLIC1
Entrez,  Source
chloride intracellular channel 112630.1230.0391No
7PSMD1PSMD1
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 115430.1050.0240No
8ALDOAALDOA
Entrez,  Source
aldolase A, fructose-bisphosphate15640.1040.0286No
9IDH3AIDH3A
Entrez,  Source
isocitrate dehydrogenase 3 (NAD+) alpha17280.0960.0219No
10SCDSCD
Entrez,  Source
stearoyl-CoA desaturase (delta-9-desaturase)18540.0900.0176No
11GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)18710.0900.0217No
12MYD88MYD88
Entrez,  Source
myeloid differentiation primary response gene (88)23320.073-0.0090No
13CCND1CCND1
Entrez,  Source
cyclin D126680.063-0.0308No
14SQLESQLE
Entrez,  Source
squalene epoxidase30910.052-0.0598No
15PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 632790.048-0.0712No
16MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1135630.042-0.0903No
17PSMD8PSMD8
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 837960.037-0.1058No
18HRASHRAS
Entrez,  Source
v-Ha-ras Harvey rat sarcoma viral oncogene homolog40550.032-0.1235No
19SYNGR2SYNGR2
Entrez,  Source
synaptogyrin 242230.029-0.1345No
20IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3043010.027-0.1388No
21PPIFPPIF
Entrez,  Source
peptidylprolyl isomerase F (cyclophilin F)43370.027-0.1399No
22ADRM1ADRM1
Entrez,  Source
adhesion regulating molecule 144430.025-0.1464No
23ODC1ODC1
Entrez,  Source
ornithine decarboxylase 145520.022-0.1533No
24CELSR2CELSR2
Entrez,  Source
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)46080.021-0.1563No
25OGFROGFR
Entrez,  Source
opioid growth factor receptor47930.019-0.1692No
26CYCSCYCS
Entrez,  Source
cytochrome c, somatic48880.017-0.1753No
27IDH1IDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble51820.012-0.1969No
28PIK3R2PIK3R2
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta)52370.011-0.2003No
29PPIBPPIB
Entrez,  Source
peptidylprolyl isomerase B (cyclophilin B)52530.011-0.2008No
30LDHALDHA
Entrez,  Source
lactate dehydrogenase A55360.007-0.2219No
31TUBG1TUBG1
Entrez,  Source
tubulin, gamma 155400.007-0.2217No
32STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa56820.005-0.2321No
33LIMK2LIMK2
Entrez,  Source
LIM domain kinase 257430.004-0.2365No
34NMT1NMT1
Entrez,  Source
N-myristoyltransferase 159070.001-0.2488No
35ATP5G3ATP5G3
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)59230.001-0.2499No
36CDC25ACDC25A
Entrez,  Source
cell division cycle 25A60020.000-0.2558No
37TOP1TOP1
Entrez,  Source
topoisomerase (DNA) I6078-0.001-0.2614No
38NDUFS6NDUFS6
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)6136-0.002-0.2656No
39ADAM19ADAM19
Entrez,  Source
ADAM metallopeptidase domain 19 (meltrin beta)6281-0.004-0.2763No
40COPS3COPS3
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)6295-0.005-0.2770No
41SF3B4SF3B4
Entrez,  Source
splicing factor 3b, subunit 4, 49kDa6322-0.005-0.2787No
42PTMSPTMS
Entrez,  Source
parathymosin6405-0.006-0.2846No
43GCSHGCSH
Entrez,  Source
glycine cleavage system protein H (aminomethyl carrier)6406-0.006-0.2842No
44GRIN2AGRIN2A
Entrez,  Source
glutamate receptor, ionotropic, N-methyl D-aspartate 2A6460-0.007-0.2878No
45NUP98NUP98
Entrez,  Source
nucleoporin 98kDa6561-0.008-0.2949No
46PSMD12PSMD12
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 126575-0.009-0.2954No
47HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 86613-0.009-0.2977No
48SLC19A1SLC19A1
Entrez,  Source
solute carrier family 19 (folate transporter), member 16656-0.010-0.3003No
49PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform6690-0.011-0.3022No
50DNAJB6DNAJB6
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 66729-0.011-0.3044No
51CCNB1CCNB1
Entrez,  Source
cyclin B16785-0.012-0.3079No
52BCAP31BCAP31
Entrez,  Source
B-cell receptor-associated protein 316822-0.012-0.3099No
53VCPVCP
Entrez,  Source
valosin-containing protein7037-0.016-0.3252No
54POLR2CPOLR2C
Entrez,  Source
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa7301-0.020-0.3441No
55UBE2NUBE2N
Entrez,  Source
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)7534-0.023-0.3603No
56PDCD4PDCD4
Entrez,  Source
programmed cell death 4 (neoplastic transformation inhibitor)7707-0.026-0.3719No
57DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase7755-0.027-0.3739No
58ACLYACLY
Entrez,  Source
ATP citrate lyase7774-0.027-0.3737No
59EIF2B4EIF2B4
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa7792-0.027-0.3734No
60KPNA2KPNA2
Entrez,  Source
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)7811-0.028-0.3732No
61PSMD3PSMD3
Entrez,  Source
proteasome (prosome, macropain) 26S subunit, non-ATPase, 37835-0.028-0.3733No
62PGAM1PGAM1
Entrez,  Source
phosphoglycerate mutase 1 (brain)7875-0.029-0.3746No
63ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 27943-0.030-0.3779No
64VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 17979-0.030-0.3788No
65PIK3R3PIK3R3
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)8161-0.033-0.3906No
66DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 18213-0.034-0.3925No
67TCEB1TCEB1
Entrez,  Source
transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)8413-0.038-0.4054No
68PRDX4PRDX4
Entrez,  Source
peroxiredoxin 48646-0.041-0.4206No
69TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein8667-0.041-0.4197No
70HPRT1HPRT1
Entrez,  Source
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)8796-0.044-0.4269No
71G3BPG3BP
Entrez,  Source
-8799-0.044-0.4245No
72RNASEH1RNASEH1
Entrez,  Source
ribonuclease H18861-0.045-0.4265No
73CALRCALR
Entrez,  Source
calreticulin9052-0.048-0.4382No
74MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 29092-0.049-0.4383No
75PRODHPRODH
Entrez,  Source
proline dehydrogenase (oxidase) 19179-0.050-0.4419No
76PSMB3PSMB3
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 39221-0.051-0.4420No
77ATP1B3ATP1B3
Entrez,  Source
ATPase, Na+/K+ transporting, beta 3 polypeptide9230-0.051-0.4396No
78PPP1R10PPP1R10
Entrez,  Source
protein phosphatase 1, regulatory subunit 109241-0.051-0.4374No
79XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)9405-0.054-0.4466No
80CTSCCTSC
Entrez,  Source
cathepsin C9429-0.055-0.4452No
81SGTASGTA
Entrez,  Source
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha9449-0.055-0.4434No
82PHBPHB
Entrez,  Source
prohibitin9567-0.057-0.4489No
83EIF5EIF5
Entrez,  Source
eukaryotic translation initiation factor 59653-0.059-0.4520No
84GMPSGMPS
Entrez,  Source
guanine monphosphate synthetase9684-0.060-0.4508No
85EBPEBP
Entrez,  Source
emopamil binding protein (sterol isomerase)9744-0.061-0.4517No
86EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 29796-0.062-0.4519No
87HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)9837-0.063-0.4513No
88MRPL23MRPL23
Entrez,  Source
mitochondrial ribosomal protein L239879-0.064-0.4507No
89PTPN6PTPN6
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 610165-0.070-0.4683Yes
90TCP1TCP1
Entrez,  Source
t-complex 110212-0.071-0.4677Yes
91CCT6ACCT6A
Entrez,  Source
chaperonin containing TCP1, subunit 6A (zeta 1)10250-0.072-0.4663Yes
92PRDX1PRDX1
Entrez,  Source
peroxiredoxin 110293-0.072-0.4653Yes
93MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L1210333-0.073-0.4639Yes
94CCT2CCT2
Entrez,  Source
chaperonin containing TCP1, subunit 2 (beta)10334-0.073-0.4596Yes
95RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 610335-0.073-0.4554Yes
96AK2AK2
Entrez,  Source
adenylate kinase 210352-0.074-0.4523Yes
97PRPF4PRPF4
Entrez,  Source
PRP4 pre-mRNA processing factor 4 homolog (yeast)10359-0.074-0.4484Yes
98GSPT1GSPT1
Entrez,  Source
G1 to S phase transition 110533-0.079-0.4570Yes
99FKBP4FKBP4
Entrez,  Source
FK506 binding protein 4, 59kDa10541-0.079-0.4529Yes
100RABGGTBRABGGTB
Entrez,  Source
Rab geranylgeranyltransferase, beta subunit10595-0.080-0.4523Yes
101RANGAP1RANGAP1
Entrez,  Source
Ran GTPase activating protein 110603-0.080-0.4482Yes
102TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)10631-0.081-0.4455Yes
103ADCY3ADCY3
Entrez,  Source
adenylate cyclase 310657-0.081-0.4426Yes
104SFRS2SFRS2
Entrez,  Source
splicing factor, arginine/serine-rich 210691-0.082-0.4403Yes
105NUDCNUDC
Entrez,  Source
nuclear distribution gene C homolog (A. nidulans)10710-0.083-0.4369Yes
106UMPSUMPS
Entrez,  Source
uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase)10783-0.085-0.4374Yes
107PSME4PSME4
Entrez,  Source
proteasome (prosome, macropain) activator subunit 410789-0.085-0.4328Yes
108RPS26RPS26
Entrez,  Source
ribosomal protein S2610813-0.086-0.4296Yes
109PFN1PFN1
Entrez,  Source
profilin 110821-0.086-0.4251Yes
110PABPN1PABPN1
Entrez,  Source
poly(A) binding protein, nuclear 110867-0.087-0.4234Yes
111RNF126RNF126
Entrez,  Source
ring finger protein 12610907-0.088-0.4212Yes
112HSPA5HSPA5
Entrez,  Source
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)10956-0.089-0.4196Yes
113C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein10991-0.090-0.4169Yes
114BZW1BZW1
Entrez,  Source
basic leucine zipper and W2 domains 111133-0.094-0.4222Yes
115DHCR7DHCR7
Entrez,  Source
7-dehydrocholesterol reductase11141-0.094-0.4172Yes
116HNRPLHNRPL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein L11160-0.095-0.4130Yes
117MTHFD1MTHFD1
Entrez,  Source
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase11221-0.096-0.4120Yes
118DKC1DKC1
Entrez,  Source
dyskeratosis congenita 1, dyskerin11229-0.096-0.4069Yes
119EWSR1EWSR1
Entrez,  Source
Ewing sarcoma breakpoint region 111248-0.097-0.4026Yes
120EIF5AEIF5A
Entrez,  Source
eukaryotic translation initiation factor 5A11294-0.098-0.4002Yes
121PTDSS1PTDSS1
Entrez,  Source
phosphatidylserine synthase 111318-0.099-0.3962Yes
122LMNB1LMNB1
Entrez,  Source
lamin B111330-0.100-0.3912Yes
123HNRPABHNRPAB
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A/B11401-0.102-0.3906Yes
124TBL3TBL3
Entrez,  Source
transducin (beta)-like 311459-0.105-0.3888Yes
125ABCF1ABCF1
Entrez,  Source
ATP-binding cassette, sub-family F (GCN20), member 111469-0.105-0.3833Yes
126CCT5CCT5
Entrez,  Source
chaperonin containing TCP1, subunit 5 (epsilon)11472-0.105-0.3774Yes
127PSMB6PSMB6
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 611483-0.105-0.3720Yes
128KARSKARS
Entrez,  Source
lysyl-tRNA synthetase11525-0.107-0.3689Yes
129BMS1LBMS1L
Entrez,  Source
BMS1-like, ribosome assembly protein (yeast)11556-0.108-0.3649Yes
130SLC5A6SLC5A6
Entrez,  Source
solute carrier family 5 (sodium-dependent vitamin transporter), member 611622-0.110-0.3634Yes
131BYSLBYSL
Entrez,  Source
bystin-like11704-0.113-0.3629Yes
132TOMM40TOMM40
Entrez,  Source
translocase of outer mitochondrial membrane 40 homolog (yeast)11720-0.114-0.3574Yes
133PAICSPAICS
Entrez,  Source
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase11730-0.114-0.3514Yes
134BOP1BOP1
Entrez,  Source
block of proliferation 111761-0.115-0.3469Yes
135PRPS1PRPS1
Entrez,  Source
phosphoribosyl pyrophosphate synthetase 111832-0.118-0.3454Yes
136PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 111848-0.119-0.3395Yes
137SSBP1SSBP1
Entrez,  Source
single-stranded DNA binding protein 111852-0.119-0.3328Yes
138FDFT1FDFT1
Entrez,  Source
farnesyl-diphosphate farnesyltransferase 111893-0.121-0.3288Yes
139DDX18DDX18
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1811900-0.122-0.3221Yes
140EIF4G1EIF4G1
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 111911-0.122-0.3158Yes
141SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like11986-0.126-0.3140Yes
142SSBSSB
Entrez,  Source
Sjogren syndrome antigen B (autoantigen La)11991-0.126-0.3070Yes
143CHD4CHD4
Entrez,  Source
chromodomain helicase DNA binding protein 412051-0.129-0.3039Yes
144FASNFASN
Entrez,  Source
fatty acid synthase12064-0.130-0.2973Yes
145XBP1XBP1
Entrez,  Source
X-box binding protein 112147-0.134-0.2957Yes
146DDX1DDX1
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 112162-0.135-0.2889Yes
147CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)12218-0.137-0.2850Yes
148ALG8ALG8
Entrez,  Source
asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase)12261-0.140-0.2801Yes
149KHSRPKHSRP
Entrez,  Source
KH-type splicing regulatory protein (FUSE binding protein 2)12267-0.140-0.2722Yes
150TARDBPTARDBP
Entrez,  Source
TAR DNA binding protein12292-0.142-0.2658Yes
151RUVBL2RUVBL2
Entrez,  Source
RuvB-like 2 (E. coli)12316-0.144-0.2591Yes
152NME1NME1
Entrez,  Source
non-metastatic cells 1, protein (NM23A) expressed in12324-0.144-0.2512Yes
153AMD1AMD1
Entrez,  Source
adenosylmethionine decarboxylase 112376-0.147-0.2465Yes
154SRPK1SRPK1
Entrez,  Source
SFRS protein kinase 112424-0.150-0.2413Yes
155NOL5ANOL5A
Entrez,  Source
nucleolar protein 5A (56kDa with KKE/D repeat)12500-0.155-0.2380Yes
156IDI1IDI1
Entrez,  Source
isopentenyl-diphosphate delta isomerase 112532-0.157-0.2312Yes
157RQCD1RQCD1
Entrez,  Source
RCD1 required for cell differentiation1 homolog (S. pombe)12533-0.157-0.2220Yes
158LAMB3LAMB3
Entrez,  Source
laminin, beta 312600-0.163-0.2175Yes
159ALG3ALG3
Entrez,  Source
asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)12651-0.168-0.2115Yes
160EIF2B5EIF2B5
Entrez,  Source
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa12669-0.170-0.2028Yes
161TRIP13TRIP13
Entrez,  Source
thyroid hormone receptor interactor 1312670-0.170-0.1929Yes
162SYNCRIPSYNCRIP
Entrez,  Source
synaptotagmin binding, cytoplasmic RNA interacting protein12730-0.176-0.1871Yes
163DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A12773-0.181-0.1797Yes
164EBNA1BP2EBNA1BP2
Entrez,  Source
EBNA1 binding protein 212803-0.186-0.1711Yes
165TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)12854-0.192-0.1637Yes
166FBLFBL
Entrez,  Source
fibrillarin12880-0.197-0.1540Yes
167SRMSRM
Entrez,  Source
spermidine synthase12882-0.197-0.1426Yes
168TDGTDG
Entrez,  Source
thymine-DNA glycosylase12893-0.199-0.1318Yes
169SLC29A2SLC29A2
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 212900-0.200-0.1206Yes
170NCLNCL
Entrez,  Source
nucleolin12916-0.202-0.1099Yes
171SLC29A1SLC29A1
Entrez,  Source
solute carrier family 29 (nucleoside transporters), member 112934-0.205-0.0992Yes
172SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 712948-0.209-0.0880Yes
173ACAT2ACAT2
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)12971-0.213-0.0772Yes
174XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)12994-0.216-0.0663Yes
175NOLC1NOLC1
Entrez,  Source
nucleolar and coiled-body phosphoprotein 113015-0.221-0.0548Yes
176PA2G4PA2G4
Entrez,  Source
proliferation-associated 2G4, 38kDa13074-0.242-0.0451Yes
177FUSFUS
Entrez,  Source
fusion (involved in t(12;16) in malignant liposarcoma)13100-0.252-0.0323Yes
178INHBCINHBC
Entrez,  Source
inhibin, beta C13106-0.255-0.0178Yes
179TFRCTFRC
Entrez,  Source
transferrin receptor (p90, CD71)13197-0.299-0.0072Yes
180SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)13213-0.3100.0098Yes
Table: GSEA details [plain text format]



Fig 2: PENG_GLUTAMINE_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: PENG_GLUTAMINE_DN: Random ES distribution   
Gene set null distribution of ES for PENG_GLUTAMINE_DN