Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_double_gel_48h.class.cls
#double_gel_8d_versus_double_gel_48h_repos
Phenotypeclass.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in classdouble_gel_8d
GeneSetPOD1_KO_DN
Enrichment Score (ES)0.48971164
Normalized Enrichment Score (NES)2.0759962
Nominal p-value0.0
FDR q-value0.0016958918
FWER p-Value0.053
Table: GSEA Results Summary



Fig 1: Enrichment plot: POD1_KO_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CLEC14ACLEC14A
Entrez,  Source
C-type lectin domain family 14, member A01.7200.0458Yes
2VIMVIM
Entrez,  Source
vimentin41.2250.0782Yes
3ANXA1ANXA1
Entrez,  Source
annexin A1110.8840.1013Yes
4RGS2RGS2
Entrez,  Source
regulator of G-protein signalling 2, 24kDa250.7710.1208Yes
5CTGFCTGF
Entrez,  Source
connective tissue growth factor270.7570.1408Yes
6RAPGEF4RAPGEF4
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 4660.6000.1539Yes
7SYCP3SYCP3
Entrez,  Source
synaptonemal complex protein 3670.5950.1697Yes
8CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A770.5600.1840Yes
9ADMADM
Entrez,  Source
adrenomedullin960.5230.1965Yes
10TACC1TACC1
Entrez,  Source
transforming, acidic coiled-coil containing protein 1990.5180.2101Yes
11CRYABCRYAB
Entrez,  Source
crystallin, alpha B1060.4940.2228Yes
12GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 51150.4840.2351Yes
13AGTR1AGTR1
Entrez,  Source
angiotensin II receptor, type 11390.4570.2454Yes
14LYZLYZ
Entrez,  Source
lysozyme (renal amyloidosis)1530.4420.2562Yes
15SGKSGK
Entrez,  Source
serum/glucocorticoid regulated kinase2000.3880.2630Yes
16PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 12030.3840.2730Yes
17OSBPL5OSBPL5
Entrez,  Source
oxysterol binding protein-like 52090.3790.2827Yes
18PLATPLAT
Entrez,  Source
plasminogen activator, tissue2300.3650.2909Yes
19SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 12310.3640.3006Yes
20AHNAKAHNAK
Entrez,  Source
AHNAK nucleoprotein (desmoyokin)2550.3380.3078Yes
21PLCL1PLCL1
Entrez,  Source
phospholipase C-like 12690.3280.3155Yes
22CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 22970.3110.3217Yes
23TCP11L2TCP11L2
Entrez,  Source
t-complex 11 (mouse) like 22990.3100.3299Yes
24TSPAN2TSPAN2
Entrez,  Source
tetraspanin 23110.2980.3370Yes
25SLCO2A1SLCO2A1
Entrez,  Source
solute carrier organic anion transporter family, member 2A13220.2920.3440Yes
26TIMP3TIMP3
Entrez,  Source
TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)3290.2910.3513Yes
27RAPGEF5RAPGEF5
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 53840.2670.3542Yes
28PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)4020.2580.3598Yes
29DPYSL2DPYSL2
Entrez,  Source
dihydropyrimidinase-like 24040.2580.3666Yes
30DNAJB4DNAJB4
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 44100.2560.3730Yes
31KLF4KLF4
Entrez,  Source
Kruppel-like factor 4 (gut)4170.2540.3793Yes
32DYNC1LI2DYNC1LI2
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 24340.2490.3847Yes
33THBDTHBD
Entrez,  Source
thrombomodulin4740.2360.3880Yes
34GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)4830.2330.3936Yes
35MGLLMGLL
Entrez,  Source
monoglyceride lipase5100.2240.3976Yes
36CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator5230.2220.4026Yes
37SPRED2SPRED2
Entrez,  Source
sprouty-related, EVH1 domain containing 25280.2210.4081Yes
38EHD3EHD3
Entrez,  Source
EH-domain containing 35590.2150.4115Yes
39DBTDBT
Entrez,  Source
dihydrolipoamide branched chain transacylase E25770.2100.4158Yes
40MYADMMYADM
Entrez,  Source
myeloid-associated differentiation marker5910.2080.4204Yes
41FLI1FLI1
Entrez,  Source
Friend leukemia virus integration 16270.2020.4230Yes
42ANXA4ANXA4
Entrez,  Source
annexin A47360.1790.4195Yes
43NFKBIANFKBIA
Entrez,  Source
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha7540.1760.4229Yes
44ITGA9ITGA9
Entrez,  Source
integrin, alpha 97670.1750.4266Yes
45FLT1FLT1
Entrez,  Source
fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)7890.1720.4296Yes
46TRAK2TRAK2
Entrez,  Source
trafficking protein, kinesin binding 28820.1580.4267Yes
47FABP4FABP4
Entrez,  Source
fatty acid binding protein 4, adipocyte8840.1580.4308Yes
48PBX2PBX2
Entrez,  Source
pre-B-cell leukemia transcription factor 29560.1510.4294Yes
49IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 19990.1470.4301Yes
50ADAMTS5ADAMTS5
Entrez,  Source
ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)10520.1410.4298Yes
51PDE4DIPPDE4DIP
Entrez,  Source
phosphodiesterase 4D interacting protein (myomegalin)10770.1380.4316Yes
52MYO1CMYO1C
Entrez,  Source
myosin IC10810.1380.4351Yes
53CASTCAST
Entrez,  Source
calpastatin10900.1370.4381Yes
54PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B11140.1350.4399Yes
55SERINC3SERINC3
Entrez,  Source
serine incorporator 311440.1330.4412Yes
56NESNES
Entrez,  Source
nestin11470.1320.4446Yes
57PDE10APDE10A
Entrez,  Source
phosphodiesterase 10A11760.1300.4459Yes
58SULF2SULF2
Entrez,  Source
sulfatase 211790.1300.4492Yes
59CAV2CAV2
Entrez,  Source
caveolin 211860.1290.4522Yes
60PTPRCPTPRC
Entrez,  Source
protein tyrosine phosphatase, receptor type, C12070.1270.4540Yes
61PCOLCEPCOLCE
Entrez,  Source
procollagen C-endopeptidase enhancer12140.1260.4569Yes
62MYO1EMYO1E
Entrez,  Source
myosin IE12280.1260.4593Yes
63SEC11L3SEC11L3
Entrez,  Source
SEC11-like 3 (S. cerevisiae)12720.1220.4592Yes
64PARP4PARP4
Entrez,  Source
poly (ADP-ribose) polymerase family, member 412740.1220.4624Yes
65PON2PON2
Entrez,  Source
paraoxonase 213010.1200.4636Yes
66TSPAN8TSPAN8
Entrez,  Source
tetraspanin 813110.1190.4661Yes
67EPAS1EPAS1
Entrez,  Source
endothelial PAS domain protein 113210.1180.4685Yes
68NID2NID2
Entrez,  Source
nidogen 2 (osteonidogen)13490.1160.4695Yes
69ATP2A3ATP2A3
Entrez,  Source
ATPase, Ca++ transporting, ubiquitous13900.1140.4695Yes
70RALBRALB
Entrez,  Source
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)14010.1130.4717Yes
71TSPAN12TSPAN12
Entrez,  Source
tetraspanin 1214310.1120.4725Yes
72PER2PER2
Entrez,  Source
period homolog 2 (Drosophila)14540.1100.4737Yes
73SH3GLB1SH3GLB1
Entrez,  Source
SH3-domain GRB2-like endophilin B114640.1100.4760Yes
74DUSP6DUSP6
Entrez,  Source
dual specificity phosphatase 615040.1080.4758Yes
75TMEM23TMEM23
Entrez,  Source
transmembrane protein 2315550.1050.4748Yes
76MYO1BMYO1B
Entrez,  Source
myosin IB15950.1030.4745Yes
77DEGS1DEGS1
Entrez,  Source
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)16210.1010.4753Yes
78SH3BP5SH3BP5
Entrez,  Source
SH3-domain binding protein 5 (BTK-associated)16590.1000.4751Yes
79PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha16630.0990.4775Yes
80LZTFL1LZTFL1
Entrez,  Source
leucine zipper transcription factor-like 117100.0970.4766Yes
81PAMCIPAMCI
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase COOH-terminal interactor17130.0970.4790Yes
82ST8SIA4ST8SIA4
Entrez,  Source
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 417180.0970.4812Yes
83YPEL5YPEL5
Entrez,  Source
yippee-like 5 (Drosophila)17330.0960.4827Yes
84P2RX4P2RX4
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 417530.0950.4838Yes
85OPTNOPTN
Entrez,  Source
optineurin17790.0940.4844Yes
86COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 418020.0930.4851Yes
87MERTKMERTK
Entrez,  Source
c-mer proto-oncogene tyrosine kinase18080.0920.4872Yes
88SLC9A3R2SLC9A3R2
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 218090.0920.4897Yes
89TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)18410.0910.4897Yes
90DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 119900.0850.4806No
91DDNDDN
Entrez,  Source
dendrin20630.0830.4773No
92PPP1R2PPP1R2
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 221000.0810.4766No
93LYSTLYST
Entrez,  Source
lysosomal trafficking regulator21070.0810.4783No
94CTTNBP2CTTNBP2
Entrez,  Source
cortactin binding protein 221530.0790.4770No
95EFNB1EFNB1
Entrez,  Source
ephrin-B121740.0780.4775No
96METRNLMETRNL
Entrez,  Source
meteorin, glial cell differentiation regulator-like21960.0770.4780No
97SDPRSDPR
Entrez,  Source
serum deprivation response (phosphatidylserine binding protein)22310.0760.4774No
98TLR4TLR4
Entrez,  Source
toll-like receptor 422870.0740.4751No
99SOS2SOS2
Entrez,  Source
son of sevenless homolog 2 (Drosophila)23020.0740.4760No
100FRKFRK
Entrez,  Source
fyn-related kinase23440.0730.4748No
101SNF1LKSNF1LK
Entrez,  Source
SNF1-like kinase23450.0730.4767No
102CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 523520.0720.4782No
103CUGBP2CUGBP2
Entrez,  Source
CUG triplet repeat, RNA binding protein 224510.0690.4725No
104ING3ING3
Entrez,  Source
inhibitor of growth family, member 324580.0690.4739No
105INPP4AINPP4A
Entrez,  Source
inositol polyphosphate-4-phosphatase, type I, 107kDa24710.0690.4748No
106IL2RGIL2RG
Entrez,  Source
interleukin 2 receptor, gamma (severe combined immunodeficiency)25820.0650.4681No
107SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 126210.0640.4668No
108MAPTMAPT
Entrez,  Source
microtubule-associated protein tau26380.0640.4673No
109GPC1GPC1
Entrez,  Source
glypican 126720.0630.4665No
110CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b26840.0630.4673No
111PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 126860.0630.4689No
112CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)27220.0620.4678No
113ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl27380.0620.4683No
114LMO7LMO7
Entrez,  Source
LIM domain 727450.0620.4695No
115RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 227900.0600.4677No
116CEBPBCEBPB
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), beta28480.0590.4649No
117HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 128800.0580.4641No
118ERGERG
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog (avian)29350.0570.4614No
119RAPGEF3RAPGEF3
Entrez,  Source
Rap guanine nucleotide exchange factor (GEF) 329500.0560.4618No
120CTBSCTBS
Entrez,  Source
chitobiase, di-N-acetyl-29900.0550.4603No
121ARRB1ARRB1
Entrez,  Source
arrestin, beta 130160.0540.4598No
122TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)30340.0540.4599No
123ZFHX1BZFHX1B
Entrez,  Source
zinc finger homeobox 1b30810.0520.4578No
124CTSSCTSS
Entrez,  Source
cathepsin S30840.0520.4590No
125BICD2BICD2
Entrez,  Source
bicaudal D homolog 2 (Drosophila)30880.0520.4602No
126VAMP5VAMP5
Entrez,  Source
vesicle-associated membrane protein 5 (myobrevin)31080.0520.4601No
127MAFBMAFB
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)31220.0510.4604No
128EHD4EHD4
Entrez,  Source
EH-domain containing 431350.0510.4609No
129RAP1BRAP1B
Entrez,  Source
RAP1B, member of RAS oncogene family31770.0500.4591No
130PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A32160.0490.4574No
131SLC12A1SLC12A1
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 132210.0490.4584No
132CLCA2CLCA2
Entrez,  Source
chloride channel, calcium activated, family member 232340.0490.4588No
133TPP1TPP1
Entrez,  Source
tripeptidyl peptidase I32940.0470.4555No
134GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 233340.0460.4538No
135TBX3TBX3
Entrez,  Source
T-box 3 (ulnar mammary syndrome)33450.0460.4542No
136ATP10AATP10A
Entrez,  Source
ATPase, Class V, type 10A33870.0450.4523No
137ROCK1ROCK1
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 133890.0450.4534No
138LYSMD3LYSMD3
Entrez,  Source
LysM, putative peptidoglycan-binding, domain containing 333960.0450.4542No
139SLC38A4SLC38A4
Entrez,  Source
solute carrier family 38, member 434360.0440.4523No
140EPN2EPN2
Entrez,  Source
epsin 234730.0440.4507No
141MPP3MPP3
Entrez,  Source
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)35530.0420.4458No
142SEMA3GSEMA3G
Entrez,  Source
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G35580.0420.4466No
143CBARA1CBARA1
Entrez,  Source
calcium binding atopy-related autoantigen 136520.0400.4405No
144FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES36620.0400.4408No
145CD47CD47
Entrez,  Source
CD47 molecule37000.0390.4390No
146SPEGSPEG
Entrez,  Source
SPEG complex locus37010.0390.4400No
147STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)37440.0380.4378No
148ABCA5ABCA5
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 538790.0350.4284No
149ACBD5ACBD5
Entrez,  Source
acyl-Coenzyme A binding domain containing 538990.0350.4279No
150PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O39440.0340.4254No
151PIK3CAPIK3CA
Entrez,  Source
phosphoinositide-3-kinase, catalytic, alpha polypeptide39500.0340.4259No
152CXCR7CXCR7
Entrez,  Source
chemokine (C-X-C motif) receptor 739530.0340.4267No
153NOTCH4NOTCH4
Entrez,  Source
Notch homolog 4 (Drosophila)39640.0330.4268No
154PDLIM2PDLIM2
Entrez,  Source
PDZ and LIM domain 2 (mystique)39750.0330.4269No
155LEPREL1LEPREL1
Entrez,  Source
leprecan-like 140240.0320.4241No
156TRPC1TRPC1
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 140540.0320.4227No
157MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 140770.0310.4218No
158DSPDSP
Entrez,  Source
desmoplakin40790.0310.4226No
159FOXC2FOXC2
Entrez,  Source
forkhead box C2 (MFH-1, mesenchyme forkhead 1)40800.0310.4234No
160TMEM33TMEM33
Entrez,  Source
transmembrane protein 3340870.0310.4238No
161SLC17A5SLC17A5
Entrez,  Source
solute carrier family 17 (anion/sugar transporter), member 542390.0280.4129No
162RBMS1RBMS1
Entrez,  Source
RNA binding motif, single stranded interacting protein 143220.0270.4074No
163CD97CD97
Entrez,  Source
CD97 molecule43420.0260.4066No
164MCL1MCL1
Entrez,  Source
myeloid cell leukemia sequence 1 (BCL2-related)43490.0260.4068No
165TMEM30ATMEM30A
Entrez,  Source
transmembrane protein 30A43810.0260.4051No
166SERINC1SERINC1
Entrez,  Source
serine incorporator 144420.0250.4012No
167SH2B3SH2B3
Entrez,  Source
SH2B adaptor protein 345230.0230.3956No
168AK1AK1
Entrez,  Source
adenylate kinase 145430.0220.3948No
169SYBL1SYBL1
Entrez,  Source
synaptobrevin-like 145970.0220.3913No
170NRP1NRP1
Entrez,  Source
neuropilin 147300.0200.3816No
171SLC33A1SLC33A1
Entrez,  Source
solute carrier family 33 (acetyl-CoA transporter), member 148930.0170.3696No
172SYNPOSYNPO
Entrez,  Source
synaptopodin48980.0170.3698No
173PRKCHPRKCH
Entrez,  Source
protein kinase C, eta49720.0160.3646No
174CALCRLCALCRL
Entrez,  Source
calcitonin receptor-like49730.0160.3650No
175ODZ2ODZ2
Entrez,  Source
odz, odd Oz/ten-m homolog 2 (Drosophila)51070.0130.3551No
176GATA3GATA3
Entrez,  Source
GATA binding protein 351240.0130.3542No
177NOSTRINNOSTRIN
Entrez,  Source
nitric oxide synthase trafficker51390.0130.3535No
178LASP1LASP1
Entrez,  Source
LIM and SH3 protein 151850.0120.3503No
179EBF1EBF1
Entrez,  Source
early B-cell factor 151930.0120.3501No
180GUCY1A3GUCY1A3
Entrez,  Source
guanylate cyclase 1, soluble, alpha 352320.0110.3475No
181CSNK1G3CSNK1G3
Entrez,  Source
casein kinase 1, gamma 352350.0110.3476No
182PDE2APDE2A
Entrez,  Source
phosphodiesterase 2A, cGMP-stimulated52640.0110.3458No
183SONSON
Entrez,  Source
SON DNA binding protein53300.0100.3410No
184ICAM2ICAM2
Entrez,  Source
intercellular adhesion molecule 254480.0080.3322No
185NID1NID1
Entrez,  Source
nidogen 155530.0070.3244No
186ATP7AATP7A
Entrez,  Source
ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)55550.0070.3245No
187PARVAPARVA
Entrez,  Source
parvin, alpha56050.0060.3209No
188SH2D4ASH2D4A
Entrez,  Source
SH2 domain containing 4A56250.0050.3196No
189BACE1BACE1
Entrez,  Source
beta-site APP-cleaving enzyme 156620.0050.3169No
190WSB2WSB2
Entrez,  Source
WD repeat and SOCS box-containing 256790.0050.3158No
191STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa56820.0050.3158No
192PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1256860.0050.3157No
193CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)57040.0040.3145No
194SACM1LSACM1L
Entrez,  Source
SAC1 suppressor of actin mutations 1-like (yeast)58240.0020.3054No
195GIMAP6GIMAP6
Entrez,  Source
GTPase, IMAP family member 658390.0020.3044No
196CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 459810.0000.2935No
197BMPR1ABMPR1A
Entrez,  Source
bone morphogenetic protein receptor, type IA6028-0.0000.2900No
198ACSL4ACSL4
Entrez,  Source
acyl-CoA synthetase long-chain family member 46090-0.0010.2853No
199PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase6132-0.0020.2822No
200WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 16150-0.0020.2810No
201PIP5K2BPIP5K2B
Entrez,  Source
phosphatidylinositol-4-phosphate 5-kinase, type II, beta6178-0.0030.2790No
202SERINC5SERINC5
Entrez,  Source
serine incorporator 56205-0.0030.2771No
203RASA2RASA2
Entrez,  Source
RAS p21 protein activator 26217-0.0030.2763No
204PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)6239-0.0040.2748No
205STXBP3STXBP3
Entrez,  Source
syntaxin binding protein 36260-0.0040.2734No
206GPSM3GPSM3
Entrez,  Source
G-protein signalling modulator 3 (AGS3-like, C. elegans)6382-0.0060.2642No
207NFIL3NFIL3
Entrez,  Source
nuclear factor, interleukin 3 regulated6595-0.0090.2482No
208GYG1GYG1
Entrez,  Source
glycogenin 16609-0.0090.2474No
209TSPAN5TSPAN5
Entrez,  Source
tetraspanin 56644-0.0100.2450No
210TCF21TCF21
Entrez,  Source
transcription factor 216717-0.0110.2398No
211DNAJB6DNAJB6
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 66729-0.0110.2392No
212ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)6774-0.0120.2362No
213EDNRBEDNRB
Entrez,  Source
endothelin receptor type B6802-0.0120.2344No
214HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase6818-0.0120.2336No
215LPHN3LPHN3
Entrez,  Source
latrophilin 36892-0.0130.2283No
216HIP1HIP1
Entrez,  Source
huntingtin interacting protein 17039-0.0160.2175No
217GRM7GRM7
Entrez,  Source
glutamate receptor, metabotropic 77064-0.0160.2161No
218LYPLA1LYPLA1
Entrez,  Source
lysophospholipase I7102-0.0170.2137No
219TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)7114-0.0170.2133No
220SCN7ASCN7A
Entrez,  Source
sodium channel, voltage-gated, type VII, alpha7130-0.0170.2126No
221CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)7147-0.0170.2119No
222CRKCRK
Entrez,  Source
v-crk sarcoma virus CT10 oncogene homolog (avian)7199-0.0180.2084No
223CDC73CDC73
Entrez,  Source
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)7218-0.0180.2075No
224RFKRFK
Entrez,  Source
riboflavin kinase7256-0.0190.2052No
225ABI3ABI3
Entrez,  Source
ABI gene family, member 37270-0.0190.2047No
226PTPRVPTPRV
Entrez,  Source
protein tyrosine phosphatase, receptor type, V (pseudogene)7287-0.0190.2040No
227UMODUMOD
Entrez,  Source
uromodulin (uromucoid, Tamm-Horsfall glycoprotein)7324-0.0200.2018No
228LMBRD1LMBRD1
Entrez,  Source
LMBR1 domain containing 17350-0.0200.2004No
229GLRX2GLRX2
Entrez,  Source
glutaredoxin 27373-0.0210.1992No
230ARAFARAF
Entrez,  Source
v-raf murine sarcoma 3611 viral oncogene homolog7415-0.0210.1966No
231EMCNEMCN
Entrez,  Source
endomucin7455-0.0220.1942No
232SIRPASIRPA
Entrez,  Source
signal-regulatory protein alpha7460-0.0220.1945No
233ETS1ETS1
Entrez,  Source
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)7566-0.0240.1870No
234ITPKBITPKB
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase B7612-0.0240.1842No
235HIVEP2HIVEP2
Entrez,  Source
human immunodeficiency virus type I enhancer binding protein 27650-0.0250.1821No
236NT5ENT5E
Entrez,  Source
5'-nucleotidase, ecto (CD73)7715-0.0260.1778No
237NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 97899-0.0290.1645No
238CAMK2DCAMK2D
Entrez,  Source
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta7932-0.0300.1628No
239PFKFB3PFKFB3
Entrez,  Source
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 37937-0.0300.1633No
240SPOPSPOP
Entrez,  Source
speckle-type POZ protein7938-0.0300.1641No
241PROS1PROS1
Entrez,  Source
protein S (alpha)7951-0.0300.1640No
242NCOR1NCOR1
Entrez,  Source
nuclear receptor co-repressor 17954-0.0300.1646No
243PDE4DPDE4D
Entrez,  Source
phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)7982-0.0300.1634No
244NSFNSF
Entrez,  Source
N-ethylmaleimide-sensitive factor8063-0.0320.1581No
245ARHGAP5ARHGAP5
Entrez,  Source
Rho GTPase activating protein 58103-0.0320.1559No
246GPR116GPR116
Entrez,  Source
G protein-coupled receptor 1168115-0.0320.1560No
247KIF5BKIF5B
Entrez,  Source
kinesin family member 5B8195-0.0340.1508No
248ELF1ELF1
Entrez,  Source
E74-like factor 1 (ets domain transcription factor)8198-0.0340.1515No
249YIPF4YIPF4
Entrez,  Source
Yip1 domain family, member 48203-0.0340.1521No
250CENTB2CENTB2
Entrez,  Source
centaurin, beta 28209-0.0340.1526No
251DSCR1L1DSCR1L1
Entrez,  Source
Down syndrome critical region gene 1-like 18243-0.0350.1510No
252CYBBCYBB
Entrez,  Source
cytochrome b-245, beta polypeptide (chronic granulomatous disease)8263-0.0350.1505No
253EPHB1EPHB1
Entrez,  Source
EPH receptor B18320-0.0360.1471No
254TMEM106BTMEM106B
Entrez,  Source
transmembrane protein 106B8374-0.0370.1441No
255ELTD1ELTD1
Entrez,  Source
EGF, latrophilin and seven transmembrane domain containing 18400-0.0370.1431No
256MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase8412-0.0380.1433No
257CYP20A1CYP20A1
Entrez,  Source
cytochrome P450, family 20, subfamily A, polypeptide 18644-0.0410.1266No
258EP300EP300
Entrez,  Source
E1A binding protein p3008660-0.0410.1265No
259TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein8667-0.0410.1272No
260LMO2LMO2
Entrez,  Source
LIM domain only 2 (rhombotin-like 1)8708-0.0420.1252No
261ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 68734-0.0430.1245No
262SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 38829-0.0440.1184No
263RIPK5RIPK5
Entrez,  Source
receptor interacting protein kinase 58851-0.0450.1180No
264GALNT10GALNT10
Entrez,  Source
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)8900-0.0460.1155No
265GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase8910-0.0460.1160No
266SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)8914-0.0460.1170No
267LNPEPLNPEP
Entrez,  Source
leucyl/cystinyl aminopeptidase8978-0.0470.1134No
268DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)8984-0.0470.1143No
269IL6STIL6ST
Entrez,  Source
interleukin 6 signal transducer (gp130, oncostatin M receptor)9035-0.0480.1117No
270GJA3GJA3
Entrez,  Source
gap junction protein, alpha 3, 46kDa (connexin 46)9083-0.0490.1094No
271GIMAP4GIMAP4
Entrez,  Source
GTPase, IMAP family member 49106-0.0490.1090No
272DLC1DLC1
Entrez,  Source
deleted in liver cancer 19141-0.0500.1077No
273HHEXHHEX
Entrez,  Source
homeobox, hematopoietically expressed9234-0.0510.1020No
274TMBIM1TMBIM1
Entrez,  Source
transmembrane BAX inhibitor motif containing 19284-0.0520.0996No
275USP33USP33
Entrez,  Source
ubiquitin specific peptidase 339360-0.0530.0953No
276EBAG9EBAG9
Entrez,  Source
estrogen receptor binding site associated, antigen, 99386-0.0540.0948No
277PLSCR4PLSCR4
Entrez,  Source
phospholipid scramblase 49499-0.0560.0877No
278VPS54VPS54
Entrez,  Source
vacuolar protein sorting 54 (S. cerevisiae)9562-0.0570.0844No
279IRS1IRS1
Entrez,  Source
insulin receptor substrate 19795-0.0620.0682No
280MORF4L1MORF4L1
Entrez,  Source
mortality factor 4 like 19926-0.0650.0599No
281ITGB5ITGB5
Entrez,  Source
integrin, beta 59946-0.0650.0602No
282PRG1PRG1
Entrez,  Source
proteoglycan 1, secretory granule10004-0.0660.0576No
283GABRA4GABRA4
Entrez,  Source
gamma-aminobutyric acid (GABA) A receptor, alpha 410121-0.0690.0505No
284GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha10152-0.0690.0500No
285CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10213-0.0710.0473No
286COLEC12COLEC12
Entrez,  Source
collectin sub-family member 1210217-0.0710.0490No
287TOB1TOB1
Entrez,  Source
transducer of ERBB2, 110294-0.0720.0450No
288SLKSLK
Entrez,  Source
STE20-like kinase (yeast)10306-0.0730.0461No
289PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)10315-0.0730.0475No
290RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 610335-0.0730.0479No
291SNRKSNRK
Entrez,  Source
SNF related kinase10380-0.0740.0465No
292TMOD3TMOD3
Entrez,  Source
tropomodulin 3 (ubiquitous)10440-0.0760.0440No
293TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)10443-0.0760.0459No
294WDR22WDR22
Entrez,  Source
WD repeat domain 2210447-0.0760.0477No
295LIFRLIFR
Entrez,  Source
leukemia inhibitory factor receptor alpha10469-0.0770.0481No
296ZHX1ZHX1
Entrez,  Source
zinc fingers and homeoboxes 110544-0.0790.0445No
297RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)10546-0.0790.0466No
298STRNSTRN
Entrez,  Source
striatin, calmodulin binding protein10568-0.0790.0470No
299JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)10575-0.0790.0487No
300TGFBR2TGFBR2
Entrez,  Source
transforming growth factor, beta receptor II (70/80kDa)10602-0.0800.0488No
301SGPP1SGPP1
Entrez,  Source
sphingosine-1-phosphate phosphatase 110634-0.0810.0486No
302PPM2CPPM2C
Entrez,  Source
protein phosphatase 2C, magnesium-dependent, catalytic subunit10699-0.0830.0459No
303TEX2TEX2
Entrez,  Source
testis expressed sequence 210702-0.0830.0479No
304ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1510705-0.0830.0500No
305FUT11FUT11
Entrez,  Source
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)10804-0.0850.0447No
306CRSP3CRSP3
Entrez,  Source
cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa10834-0.0860.0448No
307GIMAP1GIMAP1
Entrez,  Source
GTPase, IMAP family member 110862-0.0870.0450No
308ART3ART3
Entrez,  Source
ADP-ribosyltransferase 310863-0.0870.0473No
309GPD2GPD2
Entrez,  Source
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)11070-0.0920.0339No
310ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)11216-0.0960.0253No
311HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)11246-0.0970.0257No
312KLHL5KLHL5
Entrez,  Source
kelch-like 5 (Drosophila)11256-0.0970.0276No
313EXOC8EXOC8
Entrez,  Source
exocyst complex component 811304-0.0990.0266No
314VEGFVEGF
Entrez,  Source
vascular endothelial growth factor11386-0.1020.0231No
315IL13RA1IL13RA1
Entrez,  Source
interleukin 13 receptor, alpha 111405-0.1020.0244No
316PLD1PLD1
Entrez,  Source
phospholipase D1, phosphatidylcholine-specific11484-0.1050.0212No
317SLC12A2SLC12A2
Entrez,  Source
solute carrier family 12 (sodium/potassium/chloride transporters), member 211551-0.1080.0190No
318MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 211574-0.1080.0202No
319PTPRJPTPRJ
Entrez,  Source
protein tyrosine phosphatase, receptor type, J11670-0.1120.0159No
320GNB1GNB1
Entrez,  Source
guanine nucleotide binding protein (G protein), beta polypeptide 111712-0.1140.0157No
321PGGT1BPGGT1B
Entrez,  Source
protein geranylgeranyltransferase type I, beta subunit11798-0.1170.0123No
322TOP1MTTOP1MT
Entrez,  Source
topoisomerase (DNA) I, mitochondrial11935-0.1230.0051No
323TAOK1TAOK1
Entrez,  Source
TAO kinase 112009-0.1270.0029No
324RPS6KB1RPS6KB1
Entrez,  Source
ribosomal protein S6 kinase, 70kDa, polypeptide 112044-0.1290.0037No
325POLBPOLB
Entrez,  Source
polymerase (DNA directed), beta12078-0.1310.0046No
326NPR3NPR3
Entrez,  Source
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)12092-0.1310.0071No
327UBE2V2UBE2V2
Entrez,  Source
ubiquitin-conjugating enzyme E2 variant 212194-0.1360.0030No
328SAMD8SAMD8
Entrez,  Source
sterile alpha motif domain containing 812452-0.151-0.0128No
329WDFY1WDFY1
Entrez,  Source
WD repeat and FYVE domain containing 112508-0.155-0.0129No
330MTM1MTM1
Entrez,  Source
myotubularin 112542-0.158-0.0112No
331PRKAA1PRKAA1
Entrez,  Source
protein kinase, AMP-activated, alpha 1 catalytic subunit12543-0.158-0.0070No
332UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 212627-0.166-0.0090No
333TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2312662-0.169-0.0071No
334ZFRZFR
Entrez,  Source
zinc finger RNA binding protein12694-0.172-0.0049No
335LRRC33LRRC33
Entrez,  Source
leucine rich repeat containing 3312711-0.174-0.0015No
336CYP4B1CYP4B1
Entrez,  Source
cytochrome P450, family 4, subfamily B, polypeptide 112818-0.188-0.0046No
337EGFEGF
Entrez,  Source
epidermal growth factor (beta-urogastrone)12819-0.1880.0004No
338E2F5E2F5
Entrez,  Source
E2F transcription factor 5, p130-binding12993-0.216-0.0072No
339IFI35IFI35
Entrez,  Source
interferon-induced protein 3513000-0.218-0.0018No
340GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 113017-0.2220.0029No
341AVPR1AAVPR1A
Entrez,  Source
arginine vasopressin receptor 1A13040-0.2290.0073No
342ARNTARNT
Entrez,  Source
aryl hydrocarbon receptor nuclear translocator13148-0.2690.0062No
343KIF1BKIF1B
Entrez,  Source
kinesin family member 1B13231-0.3250.0085No
Table: GSEA details [plain text format]



Fig 2: POD1_KO_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: POD1_KO_DN: Random ES distribution   
Gene set null distribution of ES for POD1_KO_DN