Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | RADAEVA_IFNA_UP |
| Enrichment Score (ES) | -0.53723454 |
| Normalized Enrichment Score (NES) | -1.758894 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06470135 |
| FWER p-Value | 0.974 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IFITM2 | IFITM2 Entrez, Source | interferon induced transmembrane protein 2 (1-8D) | 254 | 0.339 | 0.0506 | No |
| 2 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 376 | 0.270 | 0.0969 | No |
| 3 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 516 | 0.223 | 0.1324 | No |
| 4 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 1132 | 0.134 | 0.1136 | No |
| 5 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2499 | 0.068 | 0.0249 | No |
| 6 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 3300 | 0.047 | -0.0255 | No |
| 7 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 4677 | 0.020 | -0.1247 | No |
| 8 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 4762 | 0.019 | -0.1271 | No |
| 9 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 5017 | 0.015 | -0.1431 | No |
| 10 | KLK3 | KLK3 Entrez, Source | kallikrein 3, (prostate specific antigen) | 5271 | 0.011 | -0.1599 | No |
| 11 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 5682 | 0.005 | -0.1898 | No |
| 12 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 6363 | -0.006 | -0.2397 | No |
| 13 | UBE2L6 | UBE2L6 Entrez, Source | ubiquitin-conjugating enzyme E2L 6 | 6782 | -0.012 | -0.2687 | No |
| 14 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 7189 | -0.018 | -0.2955 | No |
| 15 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 7693 | -0.026 | -0.3280 | No |
| 16 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 8170 | -0.033 | -0.3569 | No |
| 17 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 8269 | -0.035 | -0.3571 | No |
| 18 | UBE2D3 | UBE2D3 Entrez, Source | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 8991 | -0.047 | -0.4016 | No |
| 19 | CALR | CALR Entrez, Source | calreticulin | 9052 | -0.048 | -0.3962 | No |
| 20 | ADAR | ADAR Entrez, Source | adenosine deaminase, RNA-specific | 9289 | -0.052 | -0.4032 | No |
| 21 | IFITM3 | IFITM3 Entrez, Source | interferon induced transmembrane protein 3 (1-8U) | 9513 | -0.056 | -0.4084 | No |
| 22 | PHB | PHB Entrez, Source | prohibitin | 9567 | -0.057 | -0.4006 | No |
| 23 | PSME1 | PSME1 Entrez, Source | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 9903 | -0.064 | -0.4126 | No |
| 24 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 9977 | -0.066 | -0.4045 | No |
| 25 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10615 | -0.080 | -0.4359 | No |
| 26 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 11466 | -0.105 | -0.4783 | No |
| 27 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 12251 | -0.140 | -0.5085 | Yes |
| 28 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12302 | -0.143 | -0.4830 | Yes |
| 29 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12405 | -0.149 | -0.4601 | Yes |
| 30 | NTRK1 | NTRK1 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 1 | 12636 | -0.167 | -0.4431 | Yes |
| 31 | IL12RB2 | IL12RB2 Entrez, Source | interleukin 12 receptor, beta 2 | 12768 | -0.180 | -0.4160 | Yes |
| 32 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 12876 | -0.196 | -0.3838 | Yes |
| 33 | TUBB | TUBB Entrez, Source | tubulin, beta | 12909 | -0.201 | -0.3450 | Yes |
| 34 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 13000 | -0.218 | -0.3069 | Yes |
| 35 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 13220 | -0.317 | -0.2583 | Yes |
| 36 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13301 | -0.450 | -0.1717 | Yes |
| 37 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13335 | -0.851 | 0.0005 | Yes |
