Details for gene set RAS_ONCOGENIC

Table: GSEA Results Summary

Dataset	double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos
Phenotype	class.cls#double_gel_8d_versus_double_gel_48h_repos
Upregulated in class	double_gel_8d
GeneSet	RAS_ONCOGENIC_SIGNATURE
Enrichment Score (ES)	0.46677518
Normalized Enrichment Score (NES)	1.7873491
Nominal p-value	0.0015797789
FDR q-value	0.027811678
FWER p-Value	0.978

Table: GSEA details [plain text format]
	PROBE	GENE SYMBOL	GENE_TITLE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	FOS	FOS Entrez, Source	v-fos FBJ murine osteosarcoma viral oncogene homolog	9	0.936	0.0603	Yes
2	CCL20	CCL20 Entrez, Source	chemokine (C-C motif) ligand 20	50	0.641	0.0990	Yes
3	CXCL2	CXCL2 Entrez, Source	chemokine (C-X-C motif) ligand 2	138	0.458	0.1223	Yes
4	PRNP	PRNP Entrez, Source	prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)	141	0.455	0.1518	Yes
5	BMP2	BMP2 Entrez, Source	bone morphogenetic protein 2	164	0.430	0.1781	Yes
6	S100A6	S100A6 Entrez, Source	S100 calcium binding protein A6	365	0.274	0.1808	Yes
7	GDF15	GDF15 Entrez, Source	growth differentiation factor 15	385	0.267	0.1968	Yes
8	IER3	IER3 Entrez, Source	immediate early response 3	392	0.264	0.2135	Yes
9	CCNL1	CCNL1 Entrez, Source	cyclin L1	405	0.257	0.2293	Yes
10	DUSP5	DUSP5 Entrez, Source	dual specificity phosphatase 5	472	0.237	0.2397	Yes
11	GJB3	GJB3 Entrez, Source	gap junction protein, beta 3, 31kDa (connexin 31)	475	0.236	0.2550	Yes
12	SLC20A1	SLC20A1 Entrez, Source	solute carrier family 20 (phosphate transporter), member 1	484	0.232	0.2695	Yes
13	TNFRSF12A	TNFRSF12A Entrez, Source	tumor necrosis factor receptor superfamily, member 12A	489	0.231	0.2842	Yes
14	ANGPTL4	ANGPTL4 Entrez, Source	angiopoietin-like 4	493	0.230	0.2990	Yes
15	GJB5	GJB5 Entrez, Source	gap junction protein, beta 5 (connexin 31.1)	534	0.219	0.3102	Yes
16	PDGFA	PDGFA Entrez, Source	platelet-derived growth factor alpha polypeptide	544	0.218	0.3237	Yes
17	TGFB2	TGFB2 Entrez, Source	transforming growth factor, beta 2	659	0.195	0.3278	Yes
18	EGR1	EGR1 Entrez, Source	early growth response 1	756	0.176	0.3320	Yes
19	TIMP1	TIMP1 Entrez, Source	TIMP metallopeptidase inhibitor 1	759	0.176	0.3433	Yes
20	ARG2	ARG2 Entrez, Source	arginase, type II	799	0.170	0.3514	Yes
21	JUNB	JUNB Entrez, Source	jun B proto-oncogene	861	0.161	0.3573	Yes
22	PALMD	PALMD Entrez, Source	palmdelphin	986	0.148	0.3575	Yes
23	CXCL1	CXCL1 Entrez, Source	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	1041	0.142	0.3627	Yes
24	ADAMTS5	ADAMTS5 Entrez, Source	ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)	1052	0.141	0.3711	Yes
25	IRX2	IRX2 Entrez, Source	iroquois homeobox protein 2	1157	0.132	0.3718	Yes
26	IL1B	IL1B Entrez, Source	interleukin 1, beta	1197	0.128	0.3772	Yes
27	LIF	LIF Entrez, Source	leukemia inhibitory factor (cholinergic differentiation factor)	1203	0.127	0.3851	Yes
28	PHLDA1	PHLDA1 Entrez, Source	pleckstrin homology-like domain, family A, member 1	1221	0.126	0.3921	Yes
29	TFPI2	TFPI2 Entrez, Source	tissue factor pathway inhibitor 2	1241	0.124	0.3987	Yes
30	ZFP36	ZFP36 Entrez, Source	zinc finger protein 36, C3H type, homolog (mouse)	1260	0.123	0.4054	Yes
31	DUSP1	DUSP1 Entrez, Source	dual specificity phosphatase 1	1261	0.123	0.4133	Yes
32	KLF6	KLF6 Entrez, Source	Kruppel-like factor 6	1286	0.121	0.4194	Yes
33	EPAS1	EPAS1 Entrez, Source	endothelial PAS domain protein 1	1321	0.118	0.4245	Yes
34	SLC6A15	SLC6A15 Entrez, Source	solute carrier family 6, member 15	1417	0.112	0.4247	Yes
35	TMEM45B	TMEM45B Entrez, Source	transmembrane protein 45B	1449	0.111	0.4295	Yes
36	IER2	IER2 Entrez, Source	immediate early response 2	1461	0.110	0.4359	Yes
37	DUSP6	DUSP6 Entrez, Source	dual specificity phosphatase 6	1504	0.108	0.4397	Yes
38	FGFBP1	FGFBP1 Entrez, Source	fibroblast growth factor binding protein 1	1532	0.106	0.4446	Yes
39	NFIB	NFIB Entrez, Source	nuclear factor I/B	1582	0.103	0.4476	Yes
40	PTPRE	PTPRE Entrez, Source	protein tyrosine phosphatase, receptor type, E	1672	0.099	0.4473	Yes
41	UPP1	UPP1 Entrez, Source	uridine phosphorylase 1	1679	0.098	0.4532	Yes
42	SLC16A3	SLC16A3 Entrez, Source	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	1690	0.098	0.4588	Yes
43	SEMA4B	SEMA4B Entrez, Source	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	1786	0.093	0.4577	Yes
44	ACOT7	ACOT7 Entrez, Source	acyl-CoA thioesterase 7	1811	0.092	0.4619	Yes
45	HBEGF	HBEGF Entrez, Source	heparin-binding EGF-like growth factor	1849	0.091	0.4650	Yes
46	PRSS1	PRSS1 Entrez, Source	protease, serine, 1 (trypsin 1)	1903	0.089	0.4668	Yes
47	IL13RA2	IL13RA2 Entrez, Source	interleukin 13 receptor, alpha 2	2018	0.084	0.4636	No
48	EFNB1	EFNB1 Entrez, Source	ephrin-B1	2174	0.078	0.4570	No
49	KLF5	KLF5 Entrez, Source	Kruppel-like factor 5 (intestinal)	2220	0.077	0.4586	No
50	SERPINB5	SERPINB5 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 5	2312	0.074	0.4565	No
51	MYD88	MYD88 Entrez, Source	myeloid differentiation primary response gene (88)	2332	0.073	0.4598	No
52	DUSP4	DUSP4 Entrez, Source	dual specificity phosphatase 4	2400	0.071	0.4593	No
53	TGFA	TGFA Entrez, Source	transforming growth factor, alpha	2430	0.070	0.4617	No
54	LRRC8C	LRRC8C Entrez, Source	leucine rich repeat containing 8 family, member C	2453	0.069	0.4645	No
55	HK2	HK2 Entrez, Source	hexokinase 2	2661	0.063	0.4530	No
56	FN1	FN1 Entrez, Source	fibronectin 1	2715	0.062	0.4530	No
57	INPP1	INPP1 Entrez, Source	inositol polyphosphate-1-phosphatase	2784	0.061	0.4518	No
58	TRIB1	TRIB1 Entrez, Source	tribbles homolog 1 (Drosophila)	2792	0.060	0.4552	No
59	MAP1LC3B	MAP1LC3B Entrez, Source	microtubule-associated protein 1 light chain 3 beta	2854	0.059	0.4544	No
60	EFNA5	EFNA5 Entrez, Source	ephrin-A5	2911	0.057	0.4539	No
61	ITPR3	ITPR3 Entrez, Source	inositol 1,4,5-triphosphate receptor, type 3	2923	0.057	0.4567	No
62	CLCF1	CLCF1 Entrez, Source	cardiotrophin-like cytokine factor 1	2926	0.057	0.4603	No
63	DKK3	DKK3 Entrez, Source	dickkopf homolog 3 (Xenopus laevis)	2975	0.055	0.4602	No
64	PLAUR	PLAUR Entrez, Source	plasminogen activator, urokinase receptor	2983	0.055	0.4633	No
65	EREG	EREG Entrez, Source	epiregulin	3011	0.054	0.4647	No
66	PVR	PVR Entrez, Source	poliovirus receptor	3141	0.051	0.4583	No
67	CCNA1	CCNA1 Entrez, Source	cyclin A1	3333	0.046	0.4469	No
68	TBX3	TBX3 Entrez, Source	T-box 3 (ulnar mammary syndrome)	3345	0.046	0.4490	No
69	SDC4	SDC4 Entrez, Source	syndecan 4 (amphiglycan, ryudocan)	3385	0.045	0.4490	No
70	KCNK1	KCNK1 Entrez, Source	potassium channel, subfamily K, member 1	3612	0.041	0.4346	No
71	FBXO9	FBXO9 Entrez, Source	F-box protein 9	3689	0.039	0.4313	No
72	STX1A	STX1A Entrez, Source	syntaxin 1A (brain)	3694	0.039	0.4336	No
73	SERPINB3	SERPINB3 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 3	3699	0.039	0.4358	No
74	TIA1	TIA1 Entrez, Source	TIA1 cytotoxic granule-associated RNA binding protein	4046	0.032	0.4117	No
75	HRAS	HRAS Entrez, Source	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	4055	0.032	0.4131	No
76	MDH1	MDH1 Entrez, Source	malate dehydrogenase 1, NAD (soluble)	4125	0.030	0.4099	No
77	AKAP12	AKAP12 Entrez, Source	A kinase (PRKA) anchor protein (gravin) 12	4283	0.028	0.3998	No
78	LAMA3	LAMA3 Entrez, Source	laminin, alpha 3	4300	0.027	0.4004	No
79	PPIF	PPIF Entrez, Source	peptidylprolyl isomerase F (cyclophilin F)	4337	0.027	0.3994	No
80	CSNK1E	CSNK1E Entrez, Source	casein kinase 1, epsilon	4346	0.026	0.4005	No
81	MCL1	MCL1 Entrez, Source	myeloid cell leukemia sequence 1 (BCL2-related)	4349	0.026	0.4020	No
82	MBOAT2	MBOAT2 Entrez, Source	membrane bound O-acyltransferase domain containing 2	4376	0.026	0.4017	No
83	ODC1	ODC1 Entrez, Source	ornithine decarboxylase 1	4552	0.022	0.3899	No
84	SMTN	SMTN Entrez, Source	smoothelin	4588	0.022	0.3887	No
85	ADRB2	ADRB2 Entrez, Source	adrenergic, beta-2-, receptor, surface	4733	0.020	0.3791	No
86	SOCS1	SOCS1 Entrez, Source	suppressor of cytokine signaling 1	4762	0.019	0.3782	No
87	MMP14	MMP14 Entrez, Source	matrix metallopeptidase 14 (membrane-inserted)	4808	0.018	0.3760	No
88	HMGN3	HMGN3 Entrez, Source	high mobility group nucleosomal binding domain 3	5116	0.013	0.3536	No
89	LDLR	LDLR Entrez, Source	low density lipoprotein receptor (familial hypercholesterolemia)	5574	0.006	0.3193	No
90	CXCL5	CXCL5 Entrez, Source	chemokine (C-X-C motif) ligand 5	5599	0.006	0.3179	No
91	EHD1	EHD1 Entrez, Source	EH-domain containing 1	5701	0.004	0.3105	No
92	CSNK1D	CSNK1D Entrez, Source	casein kinase 1, delta	5941	0.001	0.2925	No
93	TOP1	TOP1 Entrez, Source	topoisomerase (DNA) I	6078	-0.001	0.2823	No
94	TNS4	TNS4 Entrez, Source	tensin 4	6324	-0.005	0.2640	No
95	ARHGEF9	ARHGEF9 Entrez, Source	Cdc42 guanine nucleotide exchange factor (GEF) 9	6676	-0.010	0.2381	No
96	COL12A1	COL12A1 Entrez, Source	collagen, type XII, alpha 1	7095	-0.017	0.2075	No
97	TPM1	TPM1 Entrez, Source	tropomyosin 1 (alpha)	7114	-0.017	0.2073	No
98	CALM2	CALM2 Entrez, Source	calmodulin 2 (phosphorylase kinase, delta)	7147	-0.017	0.2060	No
99	PPBP	PPBP Entrez, Source	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	7274	-0.019	0.1977	No
100	MTUS1	MTUS1 Entrez, Source	mitochondrial tumor suppressor 1	7482	-0.022	0.1835	No
101	IL1A	IL1A Entrez, Source	interleukin 1, alpha	7552	-0.023	0.1798	No
102	MID1	MID1 Entrez, Source	midline 1 (Opitz/BBB syndrome)	7656	-0.025	0.1736	No
103	NT5E	NT5E Entrez, Source	5'-nucleotidase, ecto (CD73)	7715	-0.026	0.1709	No
104	SERPINB2	SERPINB2 Entrez, Source	serpin peptidase inhibitor, clade B (ovalbumin), member 2	7731	-0.026	0.1715	No
105	CYP1B1	CYP1B1 Entrez, Source	cytochrome P450, family 1, subfamily B, polypeptide 1	7989	-0.031	0.1540	No
106	DDX17	DDX17 Entrez, Source	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	8274	-0.035	0.1348	No
107	FLNB	FLNB Entrez, Source	filamin B, beta (actin binding protein 278)	8583	-0.040	0.1141	No
108	ARHGAP27	ARHGAP27 Entrez, Source	Rho GTPase activating protein 27	8729	-0.043	0.1059	No
109	PTHLH	PTHLH Entrez, Source	parathyroid hormone-like hormone	8761	-0.043	0.1063	No
110	SLC2A3	SLC2A3 Entrez, Source	solute carrier family 2 (facilitated glucose transporter), member 3	8829	-0.044	0.1041	No
111	SDC1	SDC1 Entrez, Source	syndecan 1	8872	-0.045	0.1039	No
112	PTGS2	PTGS2 Entrez, Source	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	8937	-0.046	0.1021	No
113	LYN	LYN Entrez, Source	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	9007	-0.047	0.0999	No
114	SLC9A1	SLC9A1 Entrez, Source	solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive)	9115	-0.049	0.0950	No
115	HPSE	HPSE Entrez, Source	heparanase	9251	-0.052	0.0881	No
116	DLL1	DLL1 Entrez, Source	delta-like 1 (Drosophila)	9257	-0.052	0.0911	No
117	FGFR2	FGFR2 Entrez, Source	ffer syndrome, Jackson-Weiss syndrome)	9465	-0.055	0.0791	No
118	TOR1AIP1	TOR1AIP1 Entrez, Source	torsin A interacting protein 1	9727	-0.061	0.0632	No
119	CASP1	CASP1 Entrez, Source	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	10182	-0.070	0.0334	No
120	TOB1	TOB1 Entrez, Source	transducer of ERBB2, 1	10294	-0.072	0.0297	No
121	ATP2B1	ATP2B1 Entrez, Source	ATPase, Ca++ transporting, plasma membrane 1	10314	-0.073	0.0330	No
122	HIST1H1E	HIST1H1E Entrez, Source	histone cluster 1, H1e	10409	-0.075	0.0308	No
123	CYP27B1	CYP27B1 Entrez, Source	cytochrome P450, family 27, subfamily B, polypeptide 1	10490	-0.077	0.0298	No
124	MALL	MALL Entrez, Source	mal, T-cell differentiation protein-like	10580	-0.079	0.0282	No
125	KCNN4	KCNN4 Entrez, Source	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	10587	-0.080	0.0329	No
126	LGALS8	LGALS8 Entrez, Source	lectin, galactoside-binding, soluble, 8 (galectin 8)	10835	-0.086	0.0198	No
127	PBEF1	PBEF1 Entrez, Source	pre-B-cell colony enhancing factor 1	11072	-0.092	0.0080	No
128	NDRG1	NDRG1 Entrez, Source	N-myc downstream regulated gene 1	11137	-0.094	0.0092	No
129	IL11	IL11 Entrez, Source	interleukin 11	11288	-0.098	0.0043	No
130	RUNX1	RUNX1 Entrez, Source	runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)	11329	-0.100	0.0077	No
131	VEGF	VEGF Entrez, Source	vascular endothelial growth factor	11386	-0.102	0.0101	No
132	TSC22D1	TSC22D1 Entrez, Source	TSC22 domain family, member 1	11438	-0.104	0.0130	No
133	ABCA1	ABCA1 Entrez, Source	ATP-binding cassette, sub-family A (ABC1), member 1	11627	-0.110	0.0059	No
134	FOSL1	FOSL1 Entrez, Source	FOS-like antigen 1	11938	-0.123	-0.0095	No
135	GTPBP2	GTPBP2 Entrez, Source	GTP binding protein 2	12141	-0.133	-0.0161	No
136	COL27A1	COL27A1 Entrez, Source	collagen, type XXVII, alpha 1	12236	-0.139	-0.0142	No
137	SAMD8	SAMD8 Entrez, Source	sterile alpha motif domain containing 8	12452	-0.151	-0.0206	No
138	PIM1	PIM1 Entrez, Source	pim-1 oncogene	12606	-0.164	-0.0216	No
139	HNRPH1	HNRPH1 Entrez, Source	heterogeneous nuclear ribonucleoprotein H1 (H)	12830	-0.189	-0.0261	No
140	CASP2	CASP2 Entrez, Source	caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)	12967	-0.213	-0.0226	No
141	NOLC1	NOLC1 Entrez, Source	nucleolar and coiled-body phosphoprotein 1	13015	-0.221	-0.0117	No
142	G0S2	G0S2 Entrez, Source	G0/G1switch 2	13137	-0.265	-0.0036	No
143	FOXQ1	FOXQ1 Entrez, Source	forkhead box Q1	13187	-0.293	0.0117	No