Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | REGULATION_OF_G_PROTEIN_COUPLED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.8667866 |
| Normalized Enrichment Score (NES) | 2.3261395 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 25 | 0.771 | 0.1973 | Yes |
| 2 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 62 | 0.606 | 0.3510 | Yes |
| 3 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 103 | 0.505 | 0.4785 | Yes |
| 4 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 115 | 0.484 | 0.6025 | Yes |
| 5 | PLCE1 | PLCE1 Entrez, Source | phospholipase C, epsilon 1 | 203 | 0.384 | 0.6950 | Yes |
| 6 | RGS3 | RGS3 Entrez, Source | regulator of G-protein signalling 3 | 338 | 0.287 | 0.7591 | Yes |
| 7 | RGS4 | RGS4 Entrez, Source | regulator of G-protein signalling 4 | 454 | 0.244 | 0.8134 | Yes |
| 8 | RGS5 | RGS5 Entrez, Source | regulator of G-protein signalling 5 | 513 | 0.224 | 0.8668 | Yes |
| 9 | GIT1 | GIT1 Entrez, Source | G protein-coupled receptor kinase interactor 1 | 2623 | 0.064 | 0.7251 | No |
| 10 | GRK1 | GRK1 Entrez, Source | G protein-coupled receptor kinase 1 | 3952 | 0.034 | 0.6341 | No |
| 11 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 4672 | 0.021 | 0.5855 | No |
| 12 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 4733 | 0.020 | 0.5860 | No |
| 13 | GNG7 | GNG7 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 7 | 5497 | 0.007 | 0.5306 | No |
| 14 | RIC8B | RIC8B Entrez, Source | resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) | 5515 | 0.007 | 0.5312 | No |
| 15 | RGS12 | RGS12 Entrez, Source | regulator of G-protein signalling 12 | 6916 | -0.014 | 0.4297 | No |
| 16 | GRK4 | GRK4 Entrez, Source | G protein-coupled receptor kinase 4 | 6984 | -0.015 | 0.4285 | No |
| 17 | RGS9 | RGS9 Entrez, Source | regulator of G-protein signalling 9 | 7456 | -0.022 | 0.3988 | No |
| 18 | GIT2 | GIT2 Entrez, Source | G protein-coupled receptor kinase interactor 2 | 7717 | -0.026 | 0.3860 | No |
| 19 | GRK6 | GRK6 Entrez, Source | G protein-coupled receptor kinase 6 | 8007 | -0.031 | 0.3724 | No |
| 20 | RGS14 | RGS14 Entrez, Source | regulator of G-protein signalling 14 | 11575 | -0.108 | 0.1326 | No |
