Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | REN_E2F1_TARGETS |
| Enrichment Score (ES) | -0.67488873 |
| Normalized Enrichment Score (NES) | -1.9332151 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.015738316 |
| FWER p-Value | 0.322 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 4414 | 0.025 | -0.3202 | No |
| 2 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 4903 | 0.017 | -0.3494 | No |
| 3 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 6002 | 0.000 | -0.4318 | No |
| 4 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 6682 | -0.010 | -0.4782 | No |
| 5 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 7147 | -0.017 | -0.5053 | No |
| 6 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 8655 | -0.041 | -0.6001 | No |
| 7 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 9017 | -0.048 | -0.6061 | No |
| 8 | CALR | CALR Entrez, Source | calreticulin | 9052 | -0.048 | -0.5873 | No |
| 9 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 9445 | -0.055 | -0.5922 | No |
| 10 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 10547 | -0.079 | -0.6398 | Yes |
| 11 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 10691 | -0.082 | -0.6140 | Yes |
| 12 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 10783 | -0.085 | -0.5832 | Yes |
| 13 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10985 | -0.090 | -0.5583 | Yes |
| 14 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 11066 | -0.092 | -0.5234 | Yes |
| 15 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 11131 | -0.094 | -0.4864 | Yes |
| 16 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 11221 | -0.096 | -0.4503 | Yes |
| 17 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 11765 | -0.116 | -0.4397 | Yes |
| 18 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 12251 | -0.140 | -0.4140 | Yes |
| 19 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 12414 | -0.149 | -0.3600 | Yes |
| 20 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12846 | -0.192 | -0.3071 | Yes |
| 21 | NCL | NCL Entrez, Source | nucleolin | 12916 | -0.202 | -0.2224 | Yes |
| 22 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 13004 | -0.219 | -0.1316 | Yes |
| 23 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 13255 | -0.353 | 0.0065 | Yes |
