Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_double_gel_48h.class.cls #double_gel_8d_versus_double_gel_48h_repos |
| Phenotype | class.cls#double_gel_8d_versus_double_gel_48h_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | RESPONSE_TO_WOUNDING |
| Enrichment Score (ES) | 0.5466281 |
| Normalized Enrichment Score (NES) | 2.064154 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0019068994 |
| FWER p-Value | 0.064 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 9 | 0.936 | 0.0485 | Yes |
| 2 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 11 | 0.884 | 0.0949 | Yes |
| 3 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 27 | 0.757 | 0.1336 | Yes |
| 4 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 50 | 0.641 | 0.1656 | Yes |
| 5 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 56 | 0.628 | 0.1982 | Yes |
| 6 | ADM | ADM Entrez, Source | adrenomedullin | 96 | 0.523 | 0.2227 | Yes |
| 7 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 116 | 0.483 | 0.2467 | Yes |
| 8 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 138 | 0.458 | 0.2692 | Yes |
| 9 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 142 | 0.455 | 0.2929 | Yes |
| 10 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 153 | 0.442 | 0.3154 | Yes |
| 11 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 163 | 0.430 | 0.3373 | Yes |
| 12 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 230 | 0.365 | 0.3515 | Yes |
| 13 | TFPI | TFPI Entrez, Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 316 | 0.294 | 0.3605 | Yes |
| 14 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 353 | 0.281 | 0.3725 | Yes |
| 15 | TPST1 | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 418 | 0.254 | 0.3810 | Yes |
| 16 | KLRG1 | KLRG1 Entrez, Source | killer cell lectin-like receptor subfamily G, member 1 | 426 | 0.252 | 0.3937 | Yes |
| 17 | THBD | THBD Entrez, Source | thrombomodulin | 474 | 0.236 | 0.4026 | Yes |
| 18 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 506 | 0.226 | 0.4121 | Yes |
| 19 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 510 | 0.224 | 0.4237 | Yes |
| 20 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 533 | 0.219 | 0.4335 | Yes |
| 21 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 564 | 0.213 | 0.4425 | Yes |
| 22 | F9 | F9 Entrez, Source | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | 572 | 0.212 | 0.4531 | Yes |
| 23 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 579 | 0.210 | 0.4637 | Yes |
| 24 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 616 | 0.203 | 0.4716 | Yes |
| 25 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 659 | 0.195 | 0.4787 | Yes |
| 26 | IRAK2 | IRAK2 Entrez, Source | interleukin-1 receptor-associated kinase 2 | 661 | 0.195 | 0.4889 | Yes |
| 27 | CD40 | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 758 | 0.176 | 0.4908 | Yes |
| 28 | LBP | LBP Entrez, Source | lipopolysaccharide binding protein | 790 | 0.171 | 0.4975 | Yes |
| 29 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 821 | 0.166 | 0.5040 | Yes |
| 30 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 834 | 0.165 | 0.5117 | Yes |
| 31 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 837 | 0.164 | 0.5202 | Yes |
| 32 | DCBLD2 | DCBLD2 Entrez, Source | discoidin, CUB and LCCL domain containing 2 | 852 | 0.162 | 0.5277 | Yes |
| 33 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 960 | 0.151 | 0.5275 | Yes |
| 34 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 1027 | 0.144 | 0.5301 | Yes |
| 35 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 1041 | 0.142 | 0.5366 | Yes |
| 36 | IL8RA | IL8RA Entrez, Source | interleukin 8 receptor, alpha | 1056 | 0.141 | 0.5429 | Yes |
| 37 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 1126 | 0.134 | 0.5447 | Yes |
| 38 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 1243 | 0.124 | 0.5425 | Yes |
| 39 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 1274 | 0.122 | 0.5466 | Yes |
| 40 | ACVRL1 | ACVRL1 Entrez, Source | activin A receptor type II-like 1 | 1574 | 0.104 | 0.5295 | No |
| 41 | HDAC7A | HDAC7A Entrez, Source | histone deacetylase 7A | 1959 | 0.087 | 0.5050 | No |
| 42 | GNA12 | GNA12 Entrez, Source | guanine nucleotide binding protein (G protein) alpha 12 | 2156 | 0.079 | 0.4943 | No |
| 43 | CCL11 | CCL11 Entrez, Source | chemokine (C-C motif) ligand 11 | 2565 | 0.066 | 0.4668 | No |
| 44 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 2611 | 0.065 | 0.4668 | No |
| 45 | PROC | PROC Entrez, Source | protein C (inactivator of coagulation factors Va and VIIIa) | 2636 | 0.064 | 0.4684 | No |
| 46 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 2746 | 0.061 | 0.4633 | No |
| 47 | CCR2 | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 2793 | 0.060 | 0.4630 | No |
| 48 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 2848 | 0.059 | 0.4620 | No |
| 49 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 2897 | 0.057 | 0.4614 | No |
| 50 | EREG | EREG Entrez, Source | epiregulin | 3011 | 0.054 | 0.4557 | No |
| 51 | IL5 | IL5 Entrez, Source | interleukin 5 (colony-stimulating factor, eosinophil) | 3140 | 0.051 | 0.4487 | No |
| 52 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 3740 | 0.038 | 0.4054 | No |
| 53 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 3742 | 0.038 | 0.4073 | No |
| 54 | F11R | F11R Entrez, Source | F11 receptor | 3837 | 0.036 | 0.4020 | No |
| 55 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 3981 | 0.033 | 0.3930 | No |
| 56 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 4156 | 0.030 | 0.3814 | No |
| 57 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 4274 | 0.028 | 0.3740 | No |
| 58 | CD97 | CD97 Entrez, Source | CD97 molecule | 4342 | 0.026 | 0.3703 | No |
| 59 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 4483 | 0.024 | 0.3610 | No |
| 60 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 4644 | 0.021 | 0.3500 | No |
| 61 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 4705 | 0.020 | 0.3465 | No |
| 62 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 4825 | 0.018 | 0.3384 | No |
| 63 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 4838 | 0.018 | 0.3384 | No |
| 64 | F8 | F8 Entrez, Source | coagulation factor VIII, procoagulant component (hemophilia A) | 4861 | 0.017 | 0.3377 | No |
| 65 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 5249 | 0.011 | 0.3090 | No |
| 66 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 5289 | 0.010 | 0.3065 | No |
| 67 | ADORA3 | ADORA3 Entrez, Source | adenosine A3 receptor | 5346 | 0.009 | 0.3028 | No |
| 68 | ORM1 | ORM1 Entrez, Source | orosomucoid 1 | 5348 | 0.009 | 0.3032 | No |
| 69 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 5557 | 0.007 | 0.2878 | No |
| 70 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 5614 | 0.005 | 0.2839 | No |
| 71 | SIGIRR | SIGIRR Entrez, Source | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 5702 | 0.004 | 0.2775 | No |
| 72 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5981 | 0.000 | 0.2565 | No |
| 73 | TACR1 | TACR1 Entrez, Source | tachykinin receptor 1 | 5998 | 0.000 | 0.2553 | No |
| 74 | CCR4 | CCR4 Entrez, Source | chemokine (C-C motif) receptor 4 | 6053 | -0.001 | 0.2512 | No |
| 75 | CCL22 | CCL22 Entrez, Source | chemokine (C-C motif) ligand 22 | 6089 | -0.001 | 0.2487 | No |
| 76 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 6103 | -0.002 | 0.2478 | No |
| 77 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 6149 | -0.002 | 0.2445 | No |
| 78 | HRH1 | HRH1 Entrez, Source | histamine receptor H1 | 6496 | -0.008 | 0.2187 | No |
| 79 | CD40LG | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 6517 | -0.008 | 0.2176 | No |
| 80 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 6554 | -0.008 | 0.2153 | No |
| 81 | F2RL2 | F2RL2 Entrez, Source | coagulation factor II (thrombin) receptor-like 2 | 6563 | -0.009 | 0.2152 | No |
| 82 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 6591 | -0.009 | 0.2136 | No |
| 83 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 6834 | -0.013 | 0.1959 | No |
| 84 | CRP | CRP Entrez, Source | C-reactive protein, pentraxin-related | 7104 | -0.017 | 0.1765 | No |
| 85 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 7162 | -0.018 | 0.1731 | No |
| 86 | PRDX5 | PRDX5 Entrez, Source | peroxiredoxin 5 | 7418 | -0.021 | 0.1549 | No |
| 87 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7545 | -0.023 | 0.1466 | No |
| 88 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 7552 | -0.023 | 0.1473 | No |
| 89 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 7641 | -0.025 | 0.1420 | No |
| 90 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 7788 | -0.027 | 0.1324 | No |
| 91 | C2 | C2 Entrez, Source | complement component 2 | 7795 | -0.027 | 0.1334 | No |
| 92 | F10 | F10 Entrez, Source | coagulation factor X | 7895 | -0.029 | 0.1274 | No |
| 93 | CX3CR1 | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 7909 | -0.029 | 0.1279 | No |
| 94 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 7951 | -0.030 | 0.1264 | No |
| 95 | IL13 | IL13 Entrez, Source | interleukin 13 | 7984 | -0.031 | 0.1256 | No |
| 96 | ADORA2A | ADORA2A Entrez, Source | adenosine A2a receptor | 8048 | -0.032 | 0.1225 | No |
| 97 | CYBB | CYBB Entrez, Source | cytochrome b-245, beta polypeptide (chronic granulomatous disease) | 8263 | -0.035 | 0.1081 | No |
| 98 | PTAFR | PTAFR Entrez, Source | platelet-activating factor receptor | 8264 | -0.035 | 0.1100 | No |
| 99 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 8353 | -0.037 | 0.1053 | No |
| 100 | VWF | VWF Entrez, Source | von Willebrand factor | 8376 | -0.037 | 0.1055 | No |
| 101 | ALOX15 | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 8665 | -0.041 | 0.0859 | No |
| 102 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 8747 | -0.043 | 0.0820 | No |
| 103 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 8913 | -0.046 | 0.0720 | No |
| 104 | CCR3 | CCR3 Entrez, Source | chemokine (C-C motif) receptor 3 | 9334 | -0.053 | 0.0430 | No |
| 105 | ELF3 | ELF3 Entrez, Source | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 9517 | -0.056 | 0.0321 | No |
| 106 | APCS | APCS Entrez, Source | amyloid P component, serum | 9703 | -0.060 | 0.0213 | No |
| 107 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 9785 | -0.062 | 0.0184 | No |
| 108 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 9892 | -0.064 | 0.0138 | No |
| 109 | MEFV | MEFV Entrez, Source | Mediterranean fever | 10222 | -0.071 | -0.0074 | No |
| 110 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 10438 | -0.076 | -0.0197 | No |
| 111 | SELE | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 10446 | -0.076 | -0.0162 | No |
| 112 | BLNK | BLNK Entrez, Source | B-cell linker | 10728 | -0.083 | -0.0331 | No |
| 113 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 10739 | -0.084 | -0.0295 | No |
| 114 | PLG | PLG Entrez, Source | plasminogen | 10845 | -0.087 | -0.0329 | No |
| 115 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 10921 | -0.089 | -0.0339 | No |
| 116 | F2RL3 | F2RL3 Entrez, Source | coagulation factor II (thrombin) receptor-like 3 | 11037 | -0.091 | -0.0378 | No |
| 117 | LMAN1 | LMAN1 Entrez, Source | lectin, mannose-binding, 1 | 11178 | -0.095 | -0.0434 | No |
| 118 | ABCF1 | ABCF1 Entrez, Source | ATP-binding cassette, sub-family F (GCN20), member 1 | 11469 | -0.105 | -0.0598 | No |
| 119 | PLA2G2D | PLA2G2D Entrez, Source | phospholipase A2, group IID | 11529 | -0.107 | -0.0587 | No |
| 120 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 11571 | -0.108 | -0.0561 | No |
| 121 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 11644 | -0.111 | -0.0557 | No |
| 122 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 11779 | -0.116 | -0.0598 | No |
| 123 | CFHR1 | CFHR1 Entrez, Source | complement factor H-related 1 | 12082 | -0.131 | -0.0757 | No |
| 124 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 12163 | -0.135 | -0.0747 | No |
| 125 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 12338 | -0.145 | -0.0803 | No |
| 126 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 13116 | -0.257 | -0.1256 | No |
| 127 | C4BPB | C4BPB Entrez, Source | complement component 4 binding protein, beta | 13250 | -0.346 | -0.1175 | No |
| 128 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 13251 | -0.347 | -0.0992 | No |
| 129 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 13301 | -0.450 | -0.0793 | No |
| 130 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 13330 | -0.714 | -0.0439 | No |
| 131 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13335 | -0.851 | 0.0005 | No |
